Chinese herbal compound effective composite for treating dysmenorrhea and preparation method and application thereof

Abstract

The invention discloses a Chinese herbal compound effective composite and a preparation method and application thereof. The effective composite is prepared by carrying out precipitation on Chinese herbal compound water decoction consisting of Chinese angelica, szechuan lovage rhizome, rehmannia glutinosa, white paeony root, nutgrass galingale rhizome, costustoot and rhizoma corydalis by ethanol to remove impurities, then using a macroporous absorption resin column, using ethanol to carry out gradient elution and purification and recovering the solvent of eluent. The invention selects the raw materials to compose prescription compatibly according to the theory of traditional Chinese medicine and the pathogenesis of dysmenorrhea. Pharmacological tests show that the Chinese herbal compound effective composite provided by the invention has good anticoagulation, has effect of preventing formation of blood stasis, has clearer ingredients and lower untoward effect, and is expected to be developed into a novel generation of medicine for treating dysmenorrhea.

Description

Technical field [0001] The invention relates to a traditional Chinese medicine compound prescription, in particular to an effective part of a traditional Chinese medicine compound prescription, a preparation method thereof, and application thereof in preparing a medicine for treating dysmenorrhea. Background technique: [0002] Dysmenorrhea is one of the most common symptoms in gynecology. About 75% of women have dysmenorrhea. Dysmenorrhea is divided into two categories: primary and secondary; primary dysmenorrhea refers to cramping pain in the lower abdomen and waist before and during menstruation. In severe cases, it is accompanied by nausea, vomiting, and cold limbs, mostly caused by cold blood stasis This is especially common among unmarried young women. Epidemiological studies have shown that primary dysmenorrhea is currently the most common disease in gynecology. The proportion of women with primary dysmenorrhea is as high as 43% to 90% in foreign countries, and the incide...

AI Technical Summary

Problems solved by technology

Epidemiological research shows that primary dysmenorrhea is the most common disease in gynecology at present. The proportion of women with primary dysmenorrhea is as high as 43% to 90% in foreign reports, and the incidence rate of dysmenorrhea in domestic reports is 33.1%, of which primary dysmenorrhea accounts for 53.2%. Traditional Chinese medicine has a long history of treating gynecological diseases. Its treatment principle is to attack the evils and treat the symptoms when they occur, and strengthen the body when it does not occur. From the current clinical treatment of primary dysmenorrhea, the combination of syndrome differentiation and disease has become more and more unique in traditional Chinese medicine. However, most of the current compound drugs for treating dysmenorrhea have problems such as inconvenient use, large dosage, complicated ingredients, unclear effective parts, unclear material basis for the curative effect of the compound, and certain adverse reactions. Under the guidance of the theory of traditional Chinese medicine, it is necessary to develop a drug for treating dysmenorrhea with clear effective substances, definite curative effect, small side effects and convenient administration.

Images