Transdermal medicament delivery patch preparation for treating coronary heart disease and method for preparing same

A technology for coronary heart disease and drug delivery, applied in the field of medicament for treating coronary heart disease and its preparation, can solve the problems of large toxic and side effects, large damage to the human body, poor effect, etc., and achieves improving myocardial contractility, reducing the degree of pathological changes, and improving the relationship between supply and demand. Effect

Inactive Publication Date: 2010-10-06
郑延明
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The technical problem solved by the present invention is to solve the problems of oral administration of chemical medicines, large toxic and side effects, great damage to the human body, and poor therapeutic effect of oral administration, and provide a pure Chinese medici

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] A transdermal drug delivery patch preparation for the treatment of coronary heart disease. The raw materials contain ginseng, salvia, notoginseng, codonopsis, chuanxiong, cattail yellow, dongqing, fleece-flower root, gynostemma, angelica, peach kernel, hawthorn, motherwort, psoralen, and privet Zi, safflower.

[0023] The preparation method is (weight percentage):

[0024] 1. Take 9% of ginseng, 21% of salvia, 32% of Panax notoginseng, and 38% of Codonopsis pilosula, purify, dry and crush to obtain Chinese medicine powder for use;

[0025] 2. Take 12% Ligusticum chuanxiong, 24% Puhuang, 12% Maodongqing, 24% Polygonum multiflorum, 16% Gynostemma pentaphyllum, 12% Angelica sinensis, wash, dry, and crush into granules to obtain Chinese medicine granules for use;

[0026] 3. Take 7% of peach kernel, 37% of hawthorn, 11% of motherwort, 18% of psoralen, 20% of Ligustrum lucidum, and 7% of safflower.

[0027] 4. Take 6% of the traditional Chinese medicine powder from the first step, ad...

Embodiment 2

[0038] The preparation method of the transdermal drug delivery patch preparation for the treatment of coronary heart disease is (weight percentage):

[0039] 1. Take 20% of ginseng, 30% of salvia, 19% of panax notoginseng, and 31% of dangshen, purify, dry and crush to obtain Chinese medicine powder for use;

[0040] 2. Take 24% of Ligusticum chuanxiong, 12% of Puhuang, 24% of Maodongqing, 12% of Polygonum multiflorum, 9% of Gynostemma pentaphyllum, and 19% of Angelica sinensis, wash, dry and smash into granules to obtain Chinese medicine granules for use;

[0041] 3. Take 15% of peach kernel, 23% of hawthorn, 13% of motherwort, 28% of psoralen, 11% of Ligustrum lucidum, and 10% of safflower, and wash it, and then mix with Chinese medicine for use;

[0042] 4. Take 11% of the traditional Chinese medicine powder in the first step, add 89% of 35°-40° white wine, soak for 7 days and filter to obtain the filtrate;

[0043] 5. Take 75% of the filtrate from the fourth step and add 25% of purif...

Embodiment 3

[0053] The preparation method of the transdermal drug delivery patch preparation for the treatment of coronary heart disease is (weight percentage):

[0054] 1. Take ginseng 16%, salvia 45%, panax notoginseng 20%, and Codonopsis 19%, purify, dry, and crush to obtain traditional Chinese medicine powder for use;

[0055] 2. Take 15% Ligusticum chuanxiong, Puhuang 15%, Mao Dongqing 14%, Polygonum 15%, Gynostemma 17%, and Angelica 24%, wash, dry and smash into granules to obtain Chinese medicine granules for use;

[0056] 3. Take 10% of peach kernels, 25% of hawthorn, 20% of motherwort, 15% of psoralen, 15% of Ligustrum lucidum, and 15% of safflower and wash them, and then mix with Chinese medicine for later use;

[0057] 4. Take 9% of the Chinese medicine powder in the first step, add 91% of 35°-40° white wine, soak for 7 days and filter to obtain the filtrate;

[0058] 5. Take 70% of the filtrate from the fourth step and add 30% of purified water to obtain medicinal wine for use;

[0059] ...

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Abstract

The invention discloses a transdermal medicament delivery patch preparation for treating coronary heart disease and a method for preparing the same, and relates to a medicament for treating the coronary heart disease and the method for preparing the same. The transdermal medicament delivery patch preparation for treating coronary heart disease is prepared by processing ginseng, root of red-rooted salvia, radix pseudo-ginseng, pilose asiabell root, szechuan lovage rhizome, cattail pollen, pubescent holly root, tuber fleeceflower root, fiveleaf gynostemma herb, Chinese angelica, peach seed, hawthorn, motherwort herb, malaytea scurfpea fruit, glossy privet fruit and safflower serving as raw materials by a specific process. The transdermal medicament delivery patch preparation is a pure Chinese medicinal preparation and has the advantages of no chemical additive, no toxic or side effects, no harm to a human body, good therapeutic effect by external medicament administration and suitability for patients with coronary heart disease.

Description

Technical field [0001] The invention relates to a medicament for treating coronary heart disease and a preparation method thereof, in particular to a transdermal drug delivery patch preparation for treating coronary heart disease and a preparation method thereof. Background technique [0002] We know that coronary heart disease is the abbreviation of coronary atherosclerotic heart disease, now collectively referred to as ischemic heart disease. The basic pathological changes are coronary atherosclerosis and myocardial ischemia and hypoxia caused by it. According to the severity of ischemia and hypoxia and the characteristics of myocardial damage, it is often divided into hidden coronary heart disease, angina pectoris, myocardial infarction and arrhythmia. Coronary heart disease is not only the most common disease in the elderly, but also a very common cause of death. The incidence rate increases with age, and the increase in blood pressure during hypertension is also proportion...

Claims

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Application Information

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IPC IPC(8): A61K36/88A61K9/06A61K9/70A61P9/10
Inventor 郑延明
Owner 郑延明
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