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Ultraphonic elastic imaging body model and preparation method thereof

An ultrasonic elastography and phantom technology, which is applied in ultrasonic/sonic/infrasonic diagnosis, sonic diagnosis, infrasonic diagnosis, etc., can solve the problems of unstable use and storage properties, weak bonding, and easy breakage, etc., and achieves the retention period. Long, easy quality, easy condition control effect

Inactive Publication Date: 2010-10-20
SHENZHEN HUIKANG PRECISION APP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, the bond of uniform agar phantom is relatively weak, and its strength is also relatively weak, and it is easy to break under the action of small stress; Medium is unstable and easy to change with the change of ambient temperature

Method used

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  • Ultraphonic elastic imaging body model and preparation method thereof
  • Ultraphonic elastic imaging body model and preparation method thereof
  • Ultraphonic elastic imaging body model and preparation method thereof

Examples

Experimental program
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preparation example Construction

[0028] The preparation process of the ultrasound elastography phantom includes the following steps:

[0029] First, an aqueous solution of acrylamide monomer and methylenebisacrylamide is prepared.

[0030] Dissolve acrylamide and methylenebisacrylamide in high-purity deionized water at a mass ratio of 39:1, and the mass ratio of acrylamide and methylenebisacrylamide can also be 19:1 or 59:1; according to For the desired elasticity or hardness of the ultrasonic elastography phantom, estimate the concentration of the aqueous solution to be used, the concentration is 5% to 20%, and dilute the aqueous solution of acrylamide and methylenebisacrylamide to the required concentration. The elasticity or hardness of the ultrasonic elastography phantom can be adjusted by adjusting the mass ratio of acrylamide and methylenebisacrylamide (such as 39:1 or 19:1) and the concentration of its aqueous solution (such as from 5% to 10%). Hardness changes.

[0031] Secondly, according to the at...

Embodiment 1

[0037] Example 1, a method for preparing an ultrasound elastography phantom with a Young's modulus of 4.5 kPa.

[0038] (1) Prepare an aqueous solution of acrylamide monomer and methylenebisacrylamide.

[0039] Take 25ml of an aqueous solution of acrylamide monomer and methylenebisacrylamide with a mass fraction of 40%, wherein the mass ratio of acrylamide monomer and methylenebisacrylamide is 39:1, add deionized water to dilute to 200ml to obtain the concentration 5% aqueous solution.

[0040] (2) According to the attenuation coefficient that needs to be achieved, pour the ultrasonic scatterers into the aqueous solution of acrylamide monomer and methylenebisacrylamide, and make an oxygen-free environment to remove the gas in the container.

[0041] Pour the prepared aqueous solution of acrylamide monomer and methylbisacrylamide into a 500ml suction filter bottle, weigh 4g of graphite powder with a particle size of less than 20 microns into the suction filter bottle, and put ...

Embodiment 2

[0047] Example 2, a method for preparing an ultrasonic elastography phantom with a Young's modulus of 9 kPa.

[0048] (1) Prepare an aqueous solution of acrylamide monomer and methylenebisacrylamide.

[0049] Take 30ml of an aqueous solution of acrylamide monomer and methylenebisacrylamide with a mass fraction of 40%, wherein the mass ratio of acrylamide monomer and methylenebisacrylamide is 39:1, add deionized water to dilute to 200ml to obtain the concentration 6% aqueous solution.

[0050] (2) According to the required attenuation coefficient, pour the scatterer into the aqueous solution of acrylamide monomer and methylenebisacrylamide, and make an oxygen-free environment to remove the gas in the container.

[0051] Pour the prepared aqueous solution of acrylamide monomer and methylene bisacrylamide into a 500ml suction filter bottle, weigh 4g of graphite powder with a particle size of less than 20 microns into the suction filter bottle, and put in a magnetic stirrer, whil...

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Abstract

The invention relates to an ultraphonic elastic imaging body model comprising polyacrylamide hydrogel and a scatterer, wherein the polyacrylamide hydrogel forms a reticular structure to wrap the scatterer. The elasticity (or the rigidity) of the ultraphonic elastic imaging body model can be freely regulated within a larger range by regulating the concentration of an acrylamide monomer and the sound attenuation coefficient can be changed to accord with the standard of ultraphonic elastic imaging by regulating the proportion of the scatterer.

Description

【Technical field】 [0001] The invention relates to the technical field of medical polymer materials, in particular to an ultrasonic elastography phantom and a preparation method thereof. 【Background technique】 [0002] There are many types of ultrasound elastography phantoms traditionally used, and they are mostly used for B-mode ultrasound imaging, image detection and correction of Doppler ultrasound imaging equipment, and skill training for doctors and technicians. In the development of instruments and clinical application of ultrasound elastography system, it is necessary to test the quality of the system, the most critical of which is to test the accuracy and reliability. The accuracy and reliability of the measured data are directly related to tissue characterization and the accuracy and reliability of disease diagnosis. Therefore, ultrasonic elastography cannot be used to test the elasticity (or hardness) of non-standard biological tissues as a standard for instrument ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C08L33/26C08K3/04C08F220/56A61B8/00
Inventor 靳巧锋姚慧凌涛郑海荣
Owner SHENZHEN HUIKANG PRECISION APP
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