49 results about "Polyacrylamide Hydrogel" patented technology

The invention belongs to the technical field of battery dressings, and particularly relates to a wearable magnesium battery self-powered dressing for chronic wound healing and a preparation method and application thereof. A flexible conductive carbon cloth coated with a viologen-based covalent organic framework material is used as a battery positive electrode, a magnesium sheet is used as a negative electrode, polyacrylamide hydrogel is used as a solid electrolyte, and the flexible wearable self-powered dressing is assembled. The formed electrode can effectively input electrical stimulation to the wound surface, the dressing can simulate an endogenous electric field in the wound, induce migration of fibroblasts, regulate the immune microenvironment of the wound and inhibit inflammatory response, polyacrylamide is used as gel electrolyte, and the dressing has good hygroscopicity, can absorb exudate at the wound surface and keep a wet healing environment, and can be applied to the wound healing. The chronic wound healing of the rat is effectively promoted. The self-powered dressing prepared by the invention provides a reliable electrotherapy method for chronic wound healing.

The invention discloses an N-type gel ionic thermal battery, a quasi-solid gel electrolyte and a preparation method of the quasi-solid gel electrolyte, and belongs to the technical field of thermal regeneration batteries. The preparation method comprises the following steps: fully soaking polyacrylamide hydrogel in an electrolyte containing [Cu (NH3) 2] < + > / [Cu (NH3) 4] < 2 + > redox couple to obtain the quasi-solid gel electrolyte. And preparing the N-type gel ionic thermal battery by using the quasi-solid gel electrolyte. According to the prepared N-type gel ion thermal battery, the thermoelectric conversion performance such as thermoelectric potential and output power is remarkably improved through the synergistic effect of solvated structure entropy change generated by the oxidation-reduction reaction of the copper ammonia complex reaction couple and the quasi-solid gel electrolyte. The problems that research and development of an existing N-type gel ion thermal battery focuses on physical performance regulation and control of a gel matrix, thermoelectric contribution of an oxidation-reduction reaction cannot be effectively enhanced, and improvement of the Seebeck coefficient and the power density is limited can be effectively solved.

The invention discloses a high-heat-power thermoelectric cell hydrogel for low-grade heat energy collection and a preparation method thereof, and belongs to the technical field of heat energy recovery. The polyacrylamide hydrogel is selected as a substrate of the thermoelectric cell hydrogel, so that a hydrogel internal structure which is easy to regulate and control can be obtained; excellent hydrogel stretchability is obtained by using a cross-linking agent and an initiator with relatively low concentration; potassium ferricyanide and potassium ferrocyanide are used as redox ions to generate a thermoelectric effect, so that stable P-type thermal power is obtained; by using guanidine hydrochloride, the solvation entropy difference between potassium ferricyanide and potassium ferrocyanide is enlarged, and the thermal power of the hydrogel in the thermoelectric cell is greatly improved; sodium pyrrolidone carboxylate is used, so that the concentration of ions in the hydrogel is further improved, the conductivity of the thermoelectric cell hydrogel is improved, meanwhile, a hydrogen bond network between water molecules is destroyed, and the water-retaining property of the thermoelectric cell hydrogel is improved.

The invention relates to the field of oil exploitation, in particular to temperature-resistant and salt-resistant efficient gel as well as a preparation method and application thereof, which are used for solving the problems that the efficiency of the gel is influenced and the oil displacement effect is reduced due to poor high temperature resistance and salt resistance and easiness in failure of the existing polyacrylamide hydrogel. According to the preparation method, through a copolymerization technology, various monomers with excellent temperature resistance and salt resistance, such as acrylamide, methacryloyloxyethyl trimethyl ammonium chloride, 2-acrylamido-2-methylpropanesulfonic acid, a temperature-resistant monomer and a hydrophobic macromonomer, are integrated, so that the gel can bear a relatively high temperature without degradation or performance reduction; the prepared oil displacement gel has good stability in a high-salinity environment, does not lose an oil displacement effect due to the existence of salt, ensures the activity and stability of the gel in a high-temperature and high-salt-content oil reservoir environment, and obviously enhances the oil displacement efficiency of the gel in crude oil exploitation, thereby greatly improving the exploitation efficiency and recovery rate of crude oil.

The invention belongs to the technical field of flexible electronic materials, and particularly relates to conductive hydrogel with a strain monitoring function and a preparation method and application thereof. The conductive hydrogel with the strain monitoring function, provided by the invention, comprises polyacrylamide hydrogel, MXene nanosheets dispersed in the polyacrylamide hydrogel, and alcohol and water which are filled in the polyacrylamide hydrogel. The conductive hydrogel has high strength and toughness and low hysteresis quality, and can realize high sensitivity and high stability of strain sensing under the condition of not damaging the mechanical properties of the hydrogel.

The invention discloses a roof component based on evaporation and radiation collaborative cooling and preparation and construction thereof. The roof component breaks through the limitation of a single cooling mode through a multi-layer structure coupling evaporative cooling and radiation cooling technology. The reflective film specifically comprises a base layer, an evaporation radiation synergistic cooling material layer and a reflective protection layer. The synergistic material layer is formed by modifying polyacrylamide hydrogel through lithium bromide moisture absorption salt, titanium dioxide nanoparticles are embedded to improve the short-wave reflectivity and long-wave emissivity, and the synergistic material layer has the functions of radiation cooling and moisture absorption evaporation; the reflective protective layer is made of polyvinylidene fluoride-hexafluoropropylene copolymer, so that radiation cooling power is supplemented and pollution is prevented on the premise of moisture permeability; the heat entering a room is reduced by combining an evaporation radiation synergistic cooling material and a reflection protection material; by means of the roof component based on evaporation and radiation collaborative cooling, the limitation of cooling power can be broken through, the cooling effect is enhanced, and the purpose of building energy saving is achieved.

The invention discloses an alkali-activated fly ash rapid gel hole sealing material as well as a preparation method and application thereof, and belongs to the technical field of preparation of flexible hole sealing materials for gas drilling. The invention provides an alkali-activated fly ash rapid gel hole sealing material which is prepared by the following steps: mixing a polyacrylamide hydrogel precursor solution prepared from an acrylamide monomer and a cross-linking agent with fly ash, adding an alkali accelerator and a thermal initiator, and standing. The preparation method comprises the following steps: mixing an acrylamide monomer, deionized water and a cross-linking agent to obtain a polyacrylamide hydrogel precursor solution, and mixing the polyacrylamide hydrogel precursor solution with fly ash to obtain a mixed solution; mixing sodium hydroxide and deionized water to obtain an alkali accelerant; and mixing with the mixed solution, adding a thermal initiator, standing and curing to obtain the rapid gel hole sealing material. The rapid gel hole sealing material prepared by the invention can be rapidly gelated in a short time, and can well permeate into cracks for filling; after gelling, certain obdurability is achieved, deformation is achieved along with the change of the stress effect, and long-term and efficient sealing performance is achieved.

The invention discloses a construction method of an aptamer modified photonic crystal sensor for visually detecting oxytetracycline, and belongs to the technical field of sensing. In the invention, a photonic crystal array obtained by a vertical evaporation self-assembly method is combined with polyacrylamide hydrogel to form the photonic crystal hydrogel membrane material. Gold nanoparticles serve as a bridge, one side of each gold nanoparticle is connected with an amide framework of the hydrogel through chelation, the other side of each gold nanoparticle is connected with the oxytetracycline aptamer through covalent bonding, and the aptamer modified photonic crystal sensor is constructed. The oxytetracycline aptamer and oxytetracycline are highly selectively combined through pi-pi stacking and hydrogen bonds, so that the hydrogel swells, the lattice spacing of the photonic crystal is increased, a reflected signal and a structural color are subjected to red shift, and high-selectivity detection of the oxytetracycline is realized. The rapid detection requirements in the fields of food safety, environment monitoring, biological medicine and the like are met. The linear range of oxytetracycline detection is 0.1 mu g / mL-80 mu g / mL, and the lowest detection limit is 0.033 mu g / mL.

The invention belongs to the technical field of polyacrylamide hydrogel, and discloses rapid temperature-sensitive response polyacrylamide composite hydrogel as well as a preparation method and application thereof. The preparation method comprises the following steps: dissolving N-isopropylacrylamide NIPAM, acrylic acid AA, [2-(methylacryloyloxy)-ethyl] dimethyl-(3-sulfopropyl) SBMA, an initiator and a chemical cross-linking agent in an amphiphilic cellulose acetate WSCA solution, mixing and stirring until a uniform and transparent hydrogel precursor solution is formed, and carrying out cross-linking polymerization on the obtained hydrogel precursor solution to obtain the hydrogel. Finally, the polyacrylamide composite hydrogel with rapid temperature-sensitive response is generated, and the polyacrylamide composite hydrogel is marked as the WSCA-PNSA composite temperature-sensitive hydrogel. The composite thermosensitive hydrogel provided by the invention has a phospholipid-like characteristic, so that the PNIPAM hydrogel has high thermosensitive driving force while realizing rapid thermal shrinkage, skin functional recovery can be promoted, and rapid and scar-free wound healing is realized.

The application provides a lateral flow chromatography test paper and application thereof. The lateral flow chromatography test paper comprises a quality control line and an absorption pad. The lateral flow chromatography test paper further comprises an intercept line arranged between the quality control line and the absorption pad, and the material of the intercept line is one or a mixture of two or more of gelatin, carrageenan, polyacrylamide hydrogel, polyacrylic acid hydrogel, polyvinyl alcohol hydrogel or polyvinyl alcohol-sodium alginate hydrogel solution. The lateral flow chromatography test paper can improve the sensitivity of commercial test paper strips, and can be applied to new crown antigen detection, human chorionic gonadotropin detection (HCG) and cardiac troponin detection. The lateral flow chromatography test paper provided by the application can significantly improve the sensitivity by adding a cheap hydrogel intercept line after the quality control line, has good universality, and can be widely applied to various colloidal gold method test paper detection and immunofluorescence test paper detection.

The invention belongs to the technical field of functional three-dimensional composite material preparation, and particularly relates to ion-modified carrageenan-polyacrylamide composite hydrogel and a preparation method thereof.The preparation method comprises the following steps that S1, carrageenan, acrylamide and N, N-dimethylformamide are mixed and stirred to be uniform, and a mixture is obtained; the preparation method comprises the following steps: dispersing and dissolving carrageenan, polyacrylamide, N, N '-methylene bisacrylamide and 2-hydroxy-4'-(2-hydroxyethoxy)-2-methyl propiophenone in deionized water, and heating and stirring until solids are completely dissolved to obtain a carrageenan-polyacrylamide hydrogel prepolymer solution, namely a CA-PAM hydrogel prepolymer solution; s2, transferring the CA-PAM hydrogel pre-polymerized liquid into a watch glass, and refrigerating the CA-PAM hydrogel pre-polymerized liquid in an environment of 4 DEG C until the CA-PAM hydrogel pre-polymerized liquid is solidified to obtain a condensate; s3, irradiating the cured product by using an ultraviolet lamp, so as to prepare carrageenan-polyacrylamide composite hydrogel; s4, the carrageenan-polyacrylamide composite hydrogel is soaked in chlorate solutions with different concentrations respectively, and the ion modified / carrageenan-polyacrylamide composite hydrogel material is prepared.

The application discloses a crosslinking agent for degradable hydrogel and a preparation method of degradable polyacrylamide hydrogel based on the crosslinking agent; the crosslinking agent for degradable hydrogel is composed of hydantoin epoxy resin, N, N-dimethyl benzylamine and acrylamide; the degradable polyacrylamide hydrogel prepared by using the crosslinking agent comprises acrylamide, 1.8-4.6 parts of water, potassium persulfate and the crosslinking agent; the crosslinking agent for degradable hydrogel can realize the preparation of the degradable hydrogel by chemical crosslinking method, and by adjusting the crosslinking agent, the degradable hydrogel prepared based on the crosslinking agent is applicable in the temperature environment range of normal temperature to 150 DEG C, the degradable hydrogel has selectivity to gel breaking liquid, and can realize gel breaking only by adding alkaline gel breaking liquid, and the gel breaking time is adjustable in the range of 90 min to 72 h; in addition, the crosslinking agent and the preparation method of the hydrogel are simple, the conditions are easy to control, and have good market application and promotion prospect.

The application discloses a dye-free naked-eye recognizable nucleic acid culture detection counting method, and belongs to the technical field of digital nucleic acid culture. The method comprises the following steps: (1) adding water gel monomers acrylamide and methylene bisacrylamide into a loop-mediated isothermal amplification reaction system of a to-be-detected sample, and initiating crosslinking to form a water gel system; (2) isothermal amplification reaction; (3) after the amplification is completed, a magnesium pyrophosphate precipitate point formed in the water gel system is recognized and counted, and the concentration of target nucleic acid molecules in the to-be-detected sample is calculated. The application combines polyacrylamide water gel and digital LAMP, utilizes the adsorption flocculation capacity of PAM to control the LAMP reaction by-product magnesium pyrophosphate precipitation in the vicinity of a nucleic acid amplification group, forms a white point which has a clear color difference with a background, and the position and size of the white point are basically consistent with those of the nucleic acid amplification group, and thus the dye-free naked-eye recognizable nucleic acid culture counting effect is realized.

The application discloses a PAM-AA-NHS-based multifunctional biomimetic polymer adhesive for wound repair and a preparation method thereof, and belongs to the field of biomaterial preparation and biomedical application. N-hydroxysuccinimide acrylate copolymerized polyacrylamide hydrogel is used as a substrate and as a main chain network, and functionalized materials tannic acid and phenolic hydroxyl chitosan containing o-diphenol groups are introduced, so that effective adhesion can be formed at a biological tissue interface, and cross-linking can be generated with the main chain network through hydrogen bond action to form a secondary network. In addition, aldehyde group-rich oxidized dextran side chains are introduced, which can form Schiff base cross-linking with the main chain network and amino groups in the biological tissue interface to form long-acting adhesion performance. The adhesive has good tissue adhesion, biocompatibility, antibacterial activity and wound healing promotion capacity, can replace sutures, has a positive effect on the formation of new tissues and tissue healing, and is expected to be applied in clinical treatment of wound surfaces.

The invention provides a capsaicin / sodium alginate-polyacrylamide hydrogel modified PDMS antifouling coating, a preparation method and application, and belongs to the technical field of marine antifouling materials, the capsaicin / sodium alginate-polyacrylamide hydrogel modified PDMS antifouling coating comprises hydrogel, natural antifouling agent capsaicin and polydimethylsiloxane, the synthesis process is divided into three steps, and the preparation method is simple. The preparation method comprises the following steps: 1, adding natural capsaicin into the synthesis process of acrylamide hydrogel, 2, mixing a sodium alginate solution with the natural capsaicin to form a precursor solution, and adding an initiator for polymerization, and 3, slowly adding polymerized and dried capsaicin-hydrogel powder into a defoamed PDMS prepolymer mixture; natural capsaicin effectively inhibits the growth of marine fouling organisms, hydrogel is used as a toughening reservoir to continuously release an environment-friendly antifouling agent, the low-surface-energy antifouling effect and synergistic gain are achieved through the polydimethylsiloxane layer, the composite material intervenes into the biological fouling process from multiple aspects, and the composite material jointly deals with the marine organism fouling process.

The application discloses a surface double-network composite hydrogel with a three-layer structure similar to a flat worm, which comprises a graphene-containing polyacrylamide hydrogel matrix layer, and a poly-N-isopropyl acrylamide gel network thin layer formed on one side of the graphene-containing polyacrylamide hydrogel matrix layer and a poly-sodium methacrylate gel network thin layer formed on the other side of the graphene-containing polyacrylamide hydrogel matrix layer. The application forms a gel double-network structure with photothermal response and pH response on the surface of the two sides of the matrix gel, which is similar to the body structure of a flat worm in nature, in which the back skin and the belly skin sandwich the body. The application can present different initial shapes by adjusting the pH, so as to endow the application with various photothermal response complex driving modes under different initial shapes, and finally realizes the repeatable programming of the photothermal response complex deformation.

The invention relates to the technical field of batteries, in particular to a coating composition for improving leakage resistance, liquid absorption and discharge performance of a battery and application of the coating composition. The prepared coating composition comprises the following raw materials in percentage by mass: 10%-25% of a methacrylate-acrylamide block copolymer, 10%-15% of polyvinyl alcohol, 40%-53% of starch, 1%-5% of an inorganic-organic composite corrosion inhibitor, 0.5%-2% of a compound surfactant and the balance of water. The invention also provides a preparation method of the coating composition and an application of the coating composition in a zinc-manganese dry battery, and the coating composition is used for preparing coated paper so as to improve the leakage resistance, liquid absorption and discharge performance of the battery. According to the invention, the methacrylate monomer is introduced into the traditional polyacrylamide hydrogel polymerization process, so that the liquid absorption amount and the liquid absorption rate are remarkably improved, the leakage resistance of the battery is improved, the liquid absorption amount is doubled, the discharge time is prolonged by 10%, and the retention rate reaches 95% or more after the battery is naturally stored for half a year.

The application discloses a programmable deformation and oxygen production magnetic driving soft robot and a preparation method thereof, and belongs to the technical field of composite materials and photocatalysis. Hard magnetic particles (T-NdFeB) with surface modification are compounded into kappa-carrageenan / polyacrylamide (KC / PAm) hydrogel through a free radical polymerization process to obtain a magnetic driving module. The modules are flexibly assembled into a soft robot with complex geometric shape and magnetization distribution by using a self-healing process between the modules, so that the soft robot can realize various programmable deformations. In addition, a Ru-Bi2CrO6 photocatalyst is obtained by doping Ru elements in Bi2CrO6, and is compounded into the KC / PAm hydrogel to construct a functional module capable of producing oxygen. The magnetic driving module and the functional module are further assembled into a magnetic oxygen production soft robot, so that the purpose of stably and flexibly supplying oxygen to a water environment is achieved.

A polyacrylamide-based aerogel may be an efficient solar vapor generation device. Internal pores of the polyacrylamide-based aerogel may provide capillary forces while elongated surface channels provide a transport force in response to the polyacrylamide-based aerogel contacting liquid. The polyacrylamide-based aerogel may be formed from a photocurable resin doped with reduced graphene oxide particles. The photocurable resin may be printed in layers in a micro continuous liquid interface projection process to form a polyacrylamide-based hydrogel. The polyacrylamide-based hydrogel may be immersed in water to form a swollen hydrogel structure. The swollen hydrogel structure may be frozen. The frozen hydrogel structure may be dried to form a polyacrylamide-based aerogel structure.

The present invention discloses an ultra-high-strength carbon material and a preparation method thereof, which belongs to the field of carbon material technology. The preparation method comprises the following steps: reinforcing particles, acrylamide, water-soluble sugars, N,N'-methylenebisacrylamide, an initiator and a catalyst are added to deionized water and mixed evenly, and then dried, heat-treated, crushed and ball-milled in sequence to obtain a composite powder; the composite powder is molded and carbonized in sequence to obtain the ultra-high-strength carbon material. The present invention significantly simplifies the production process of graphite block carbon materials by adopting an innovative two-step preparation process, and effectively overcomes the problems of complex process, long production cycle, high raw material cost and difficult control of microstructure in the prior art. The strategy of combining sugar-polyacrylamide hydrogel technology with reinforcing particles is used to greatly improve the carbon yield and reduce the carbon loss caused by gas release during the carbonization process, thereby optimizing the microstructure of the material and improving its mechanical properties, including key indicators such as compressive and flexural strength.

A preparation method of a nanofiber membrane with multiple response stimuli comprises the following steps: firstly dissolving MXene powder and PVDF in a DMF solution, then heating and stirring to obtain a uniform black mixed solution, and then spinning the black mixed solution through an electrostatic spinning process to prepare a PVDF-MXene nanofiber membrane; the preparation method comprises the following steps: dissolving an acrylamide monomer and an initiator in a silane cross-linking agent solution, stirring at normal temperature until the solution is in a semitransparent state to obtain a hydrogel solution, and introducing nitrogen into the hydrogel solution to obtain polyacrylamide hydrogel; the preparation method comprises the following steps: preparing polyacrylamide hydrogel into a PAM hydrogel nanofiber film through an electrostatic spinning process, and compounding a PVDF-MXene nanofiber film with the PAM hydrogel nanofiber film to obtain the Janus nanofiber film with a double-layer structure. The material can respond to multiple stimuli, and the stability is good through chemical bond connection.

The application provides a kind of molecular self-assembly triplet-triplet annihilation (TTA) photonic upconversion hydrogel and its preparation method and application, select polyethylene oxide-polypropylene oxide-polyethylene oxide (PEO-PPO-PEO) F127 three-block polymer to encapsulate upconversion dye pair, form nanomicelles.Utilize three-block polymer hydrophilic section PEO and hydrophobic section PPO in aqueous solution self-assembly to form nanoparticles, hydrophilic end is exposed outside, form dense oxygen barrier shell, hydrophobic end and hydrophobic luminescent material in core, avoid being quenched by oxygen in air.Again, add aqueous solution containing upconversion nanoparticles into acrylamide aqueous solution, directly polymerize, obtain upconversion hydrogel.The strategy is not only simple operation, without complex modification to luminescent material, and does not contain volatile organic solvent, and polyacrylamide hydrogel also has good biocompatibility, so it has great application prospect in biological field.

The application discloses a method for in-situ preparation of polyacrylamide hydrogel electrolyte at room temperature. The method directly utilizes the inherent reducibility of anode metal zinc, guides ammonium persulfate in a gel precursor solution placed between two zinc sheets or zinc sheets and positive electrode sheets to generate free radicals, so as to initiate a polymerization reaction. Compared with a conventional thermal polymerization and photopolymerization method for preparing hydrogel, the method can be completed in a short time at room temperature, and the prepared hydrogel electrolyte has good combination capacity with electrodes, and the stability of a battery is significantly improved.

The application relates to a directional radiation regulated high-thermal-resistance energy-saving wall body and a management and control method and a preparation method thereof, solves the technical problems that the prior art lacks cross-season adaptation capability, is effective in a single season but unbalanced in cross seasons, and cannot meet the winter and summer thermal working requirements in cooperation, and the wall body comprises a three-layer composite structure: an outer layer of a white cement matrix with low iron and manganese content, which can realize high reflection of a sunlight spectrum and high emission of an atmospheric window band; a middle layer of composite white cement, polyacrylamide hydrogel, hollow glass microbeads and phase change material microcapsules, the hydrogel forms a three-dimensional network to fix and disperse components, the glass microbeads construct multistage pores to strengthen thermal resistance, and the phase change microcapsules store and release heat to stabilize temperature difference; and an inner layer of an electrostatic spraying metal powder layer, which has low infrared band emissivity and realizes directional radiation regulation. The application has the following effects: realizing cross-season precise adaptation of winter heat preservation and summer heat insulation, breaking through the limitation of "single-season effectiveness", greatly reducing building energy consumption, and significantly improving indoor thermal comfort stability.

The invention belongs to the technical field of hydrogel materials, and particularly relates to water-retaining phosphorus-absorbing hydrogel as well as a preparation method and application thereof. The water-retaining and phosphorus-absorbing hydrogel provided by the invention comprises synthetic high-molecular hydrogel grafted with cellulose and chitosan and a metal organic framework loaded on the surface of the synthetic high-molecular hydrogel and the inner surfaces of holes, the polymer hydrogel comprises polyacrylic acid hydrogel and / or polyacrylamide hydrogel; the cellulose and the chitosan are grafted on carbon atoms of the synthesized polymer hydrogel through hydroxyl groups, and the polymer hydrogel is high in water absorption performance, high in phosphorus adsorption performance and friendly to natural water bodies.

The application discloses a preparation method of a hydrogel immobilized composite enzyme, and a product and application thereof. Due to the protection of bacterial cell walls, the removal efficiency of resistant genes in traditional processes is low. The application utilizes polyacrylamide hydrogel to jointly immobilize laccase, hydrolase and nuclease, so that the enzymes are effectively coated inside the carrier, the problems of easy loss and easy reduction of activity of free enzymes are avoided, and the reusability is good, and no secondary pollution is generated. The laccase is used to reduce the concentration of sulfadiazine, the hydrolase is used to hydrolyze the bacterial cell walls to release intracellular ARG, and the nuclease is used to degrade the released intracellular ARG, so that the purpose of quickly eliminating ARG in water is achieved. The method has high removal efficiency on ARG and sulfadiazine, is simple, efficient and safe, is suitable for remediation treatment of aquaculture wastewater containing antibiotic and ARG pollution, and solves the problems of poor environmental stability of water-soluble enzymes and difficult recycling.

The invention belongs to the technical field of biomedical materials, and particularly relates to a COFs (covalent organic frameworks)-based conductive hydrogel material and application of the COFs-based conductive hydrogel material in electric-assisted promotion of healing of diabetic wounds. The preparation method comprises the following steps: forming a covalent organic framework, enabling the covalent organic framework to grow on reduced graphene oxide in situ to form a nano material with a highly-ordered porous crystal structure, loading the nano material to form polyacrylamide hydrogel, and preparing the flexible hydrogel material into the multifunctional patch through a flexible electrode system. Through a triple synergistic mechanism of photo-thermal sterilization, electrochemical ROS cleaning and cell / immune regulation, the microenvironment obstacle of diabetes wound healing is broken through, ordered collagenous fiber deposition and angiogenesis are promoted, and tissue mechanical strength and blood supply reconstruction are improved. Scar formation is reduced, and the skin barrier function integrity is recovered. And through the flexible wearable characteristic, the problems of portability and comfort pain points of clinical treatment are solved, and intelligent wireless control provides technical support for precise medical treatment.

The application discloses a kind of high elastic toughness antibacterial nanocomposite conductive hydrogel material and its preparation method and biomimetic sensing application, belong to the field of functional polymer materials.The application uses melamine foam as porous elastic skeleton, is modified in situ on foam skeleton growth polypyrrole nanoparticles, subsequently polymerizes polydopamine-polyacrylamide hydrogel network in its inside, obtains the multifunctional nanocomposite conductive hydrogel with stable interpenetrating structure.The composite conductive hydrogel of the application has the synergistic effect formed by electronic conduction and ionic conduction, not only has excellent conductivity (up to 12 mS·cm ‑1 ), but also has high elastic toughness and reversible compression performance, has excellent pressure sensing performance under low pressure (0.3 kPa), so as to realize efficient information transmission and encryption application as a pressure sensor.

This invention provides a capsaicin / sodium alginate-polyacrylamide hydrogel-modified PDMS antifouling coating, its preparation method, and its application, belonging to the field of marine antifouling materials technology. It comprises three components: hydrogel, the natural antifouling agent capsaicin, and polydimethylsiloxane. The synthesis process consists of three steps: first, adding natural capsaicin to the acrylamide hydrogel synthesis process; second, mixing sodium alginate solution with capsaicin to form a precursor solution, which is then added to an initiator for polymerization; and third, slowly adding the polymerized and dried capsaicin-hydrogel powder to a degassed PDMS prepolymer mixture. This invention effectively inhibits the growth of marine fouling organisms with natural capsaicin, utilizes the hydrogel as a toughening reservoir to continuously release an environmentally friendly antifouling agent, and achieves low surface energy antifouling through the polydimethylsiloxane layer, resulting in synergistic benefits. By intervening in the biofouling process from multiple angles, the composite material jointly addresses marine biofouling.

A method of preparing a hydrogel array comprising a multi-well plate includes preparing a polyacrylamide (PA) hydrogel with alternating stiffnesses. Preparing the PA hydrogel includes preparing a polymer solution, plasma treating the multi-well plate, attaching a patterned mask to a plate containing the polymer solution, the plate comprising a plurality of wells, and treating the polymer solution with UV light to form the PA hydrogel, the PA hydrogel having first regions with a first stiffness and second regions with a second stiffness, the first stiffness being greater than the second stiffness.