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Traditional Chinese medicinal compound for treating rheumatism and preparation process thereof

A composition and technology for rheumatism, applied in the direction of drug combinations, medical preparations containing active ingredients, antipyretics, etc., to achieve the effect of wide distribution, low price, and safe medication

Active Publication Date: 2014-05-07
陈纪藩 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Studies have shown that these preparations can significantly reduce joint pain and eliminate joint swelling, but the effect of improving joint dysfunction, joint destruction and deformity is still unsatisfactory, which affects further application

Method used

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  • Traditional Chinese medicinal compound for treating rheumatism and preparation process thereof
  • Traditional Chinese medicinal compound for treating rheumatism and preparation process thereof
  • Traditional Chinese medicinal compound for treating rheumatism and preparation process thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] Recipe: Snakevine 40kg, Eucommia 20kg, Salvia miltiorrhiza 20kg, Lycium barbarum 20kg, Ligustrum lucidum 20kg and Eclipta 20kg.

[0032] Preparation method (mixture): Submerge Snakevine in water, fry for 3.5-7 hours first, then add Eucommia ulmoides, Salvia miltiorrhiza, Lycium barbarum, Ligustrum lucidum and Eclipta chinensis for 0.5-1 hour, filter, and concentrate the filtrate to about 90,000 ml, add 0.1% ethylparaben, 0.3% sodium benzoate and stir to dissolve, let cool, adjust the liquid to the full amount, filter, and subpackage after passing the test. Prepare 90,000 milliliters of oral liquid (mixture).

Embodiment 2

[0034] Recipe: Snakevine 60kg, Eucommia 20kg, Salvia miltiorrhiza 20kg, Lycium barbarum 20kg, Ligustrum lucidum 20kg and Eclipta 20kg.

[0035] Preparation method (capsule): Submerge Kunming Begonia in water, fry for 3.5-7 hours first, add Eucommia ulmoides, Salvia miltiorrhiza, wolfberry, Ligustrum lucidum and Eclipta chinensis together for 0.5-1 hour, filter, concentrate under reduced pressure, the pressure is -0.08Mpa, the temperature is 50°C-80°C, concentrate and measure the clear paste with a relative density of 1.18-1.20, dry it at 65°C to obtain a dry extract, crush it, pass through a 60-mesh sieve, and pack No. 0 capsules. Prepared into capsules.

Embodiment 3

[0037]Formula: 20kg of Snakevine, 20kg of Eucommia, 20kg of Salvia, 20kg of Lycium barbarum, 20kg of Ligustrum lucidum and 20kg of Eclipta.

[0038] Preparation method (tablet): Submerge Kunming Begonia in water, first fry for 3.5-7 hours, then add Eucommia ulmoides, Salvia miltiorrhiza, Lycium barbarum, Ligustrum lucidum and Eclipta chinensis for 0.5-1 hour, filter, concentrate under reduced pressure, pressurize It is -0.08Mpa, the temperature is 50°C-80°C, concentrate and measure the clear paste with a relative density of 1.18-1.20, dry it at 65°C to obtain a dry extract, crush it, pass through a 100-mesh sieve, weigh it, and add an appropriate proportion of carboxymethyl Sodium starch glycolate, mixed evenly, granulated with ethanol, dried, sized, weighed, added with an appropriate proportion of magnesium stearate, compressed into tablets, coated with a water-soluble film coating, packaged and stored. Prepared as tablets.

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Abstract

The invention relates to a traditional Chinese medicinal compound for treating rheumatism and a preparation method thereof. The traditional Chinese medicinal compound is prepared from the following raw material medicaments in part by weight: 1 to 7 parts of celastrus orbiculatus, 1 part of eucommia bark, 1 part of root of red-rooted salvia, 1 part of Chinese wolfberry, 1 part of glossy privet fruit and 1 part of yerbadetajo herba ecliptae. The preparation method comprises the following steps of: weighing the celastrus orbiculatus, the eucommia bark, the root of red-rooted salvia, the Chinese wolfberry, the glossy privet fruit and the yerbadetajo herba ecliptae according to prescription dose, immersing the celastrus orbiculatus into water, decocting the celastrus orbiculatus for 3.5 to 7 hours, adding the eucommia bark, the root of red-rooted salvia, the Chinese wolfberry, the glossy privet fruit and the yerbadetajo herba ecliptae, decocting the mixture for 0.5 to 1 hour, and filtering to prepare required formulations further according to a conventional method. The traditional Chinese medicinal compound is a medicament which has the advantage of capability of addressing both the symptoms an root causes, good curative effect and small toxic and side effect and is used for treating rheumatism such as RA, AS, SLE, OA and the like; and in addition, the preparation method is simple.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for treating rheumatism and a preparation process thereof. technical background [0002] Rheumatism is a group of diseases involving the bones, joints, muscles and their soft tissues. Among them, Rheumatoid Arthritis (RA), Ankylosing Spondilitis (AS), Psoriatic Arthritis (PsA), Systemic Lupus Erythematosus (SLE), multiple Myositis (Polymyositis, PM) / dermatomyositis (Dermatomyositis, DM) and systemic vasculitis (Systemic Vasculitis) are several common rheumatic diseases, and their common feature is that the patient's autoimmune dysfunction causes muscle, bone, Clinical manifestations such as joint pain or swelling, the harm caused by these rheumatic diseases, people use 5 D to summarize: disability (Disability), pain (Discomfort), death (Death), economic loss (Dollar lost) and drug poisoning (Drug toxicity) ). Therefore, countries all over the world are working hard to find efficien...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/815A61P29/00A61P19/02
Inventor 陈纪藩陈光星
Owner 陈纪藩
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