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Ordered coatings for drug eluting stents and medical devices

A coating and layered technology, applied in coating, medical science, surgery, etc., can solve problems such as vascular restenosis

Active Publication Date: 2010-12-08
MEDTRONIC VASCULAR INC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, a significant proportion of treated vessels can restenosis shortly after surgery

Method used

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  • Ordered coatings for drug eluting stents and medical devices
  • Ordered coatings for drug eluting stents and medical devices
  • Ordered coatings for drug eluting stents and medical devices

Examples

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Embodiment Construction

[0019] Throughout the specification, like numerals indicate like structures.

[0020] The invention relates to a system for treating abnormalities in the cardiovascular system, which includes a catheter and a stent carrying a therapeutic agent arranged on the catheter. The layered coating disposed on the surface of the stent is capable of releasing one or more therapeutic agents in an ordered sequence. In an exemplary embodiment of the present invention, figure 1 A system 100 is shown that includes a therapeutic agent-carrying stent 120 coupled to a catheter 110 . Catheter 110 includes a balloon 112 that inflates and deploys a therapeutic agent-carrying stent 120 within a subject's blood vessel. After the therapeutic agent-carrying stent 120 is placed into the blood vessel with the help of a guide wire traversing the guide wire lumen 114 in the catheter 110, the lumen in the catheter 110 and the balloon 112 are pressurized filled with contrast solution or saline solution. T...

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Abstract

A system for treating a vascular condition comprises a therapeutic agent eluting stent having a layered coating on the stent framework. The coating releases therapeutically effective amounts of one or more therapeutic agents in and ordered sequence and over a selected time period. Another embodiment of the invention includes a method of treating a vascular condition by placing a stent having a layered coating at a treatment site and delivering a therapeutically effective amount of one or more therapeutic agents at the treatment site in an ordered sequence and over a selected time period.

Description

technical field [0001] The present invention generally relates to biomedical devices useful in the treatment of vascular disease. More particularly, the present invention relates to therapeutic agent eluting stents and other medical devices having layered coatings that release one or more therapeutic agents in a predetermined sequence at a therapeutically optimal rate. Background of the invention [0002] Stents are typically cylindrical devices that expand radially after implantation in a body lumen to keep the lumen of a vessel segment or other anatomical structure open. [0003] Various types of stents are in use, including expandable and self-expanding stents. Expandable stents are typically delivered on a balloon catheter or other expandable device to the area to be treated. For insertion into the body, the stent is held in a compressed configuration on the delivery device. For example, the stent may be crimped over a balloon, folded or otherwise wrapped around the d...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L31/10A61L31/16
CPCA61L31/10A61L2420/08A61L2300/602A61L31/16A61L2300/00
Inventor E·泰德斯奇R·弗兰西斯M·伯德塞尔
Owner MEDTRONIC VASCULAR INC