Easy and painless drug infusion device

Abstract

The invention relates to a painless medicine transfusion device which is convenient to use, economical and practical for long-term administration, and belongs to the field of medical technology. The feature of the drug infusion device is that the device contains hidden elastic microneedles, which can be automatically retracted after instantaneous transdermal drug delivery, which not only ensures painless and efficient drug delivery, but also avoids the problems of the original microneedle drug delivery technology. Problems such as skin allergies and inflammation caused by long-term subcutaneous needle embedding; the device contains at least one independent drug infusion unit, which uses the solid drug to be administered and the driving fluid to be safely stored separately, and is only mixed at the moment of drug infusion Dissolved and injected subcutaneously via a microneedle. This new mode of solid-liquid separate storage and instant dissolving and transfusion solves technical bottlenecks such as the difficulty of storing certain drug solutions at room temperature and the need for refrigeration; the device controls drug application manually or by using an external reusable electronic automatic pressure application , which greatly reduces the manufacturing cost of the device and the consumption burden of ordinary patients; the device has excellent functions such as moisture-proof, sweat-permeable, and pressure-proof, making it more comfortable and safe to use; the device can be worn for a long time, or it can be taken with you as needed Subcutaneous administration, flexible and convenient to use. The device is suitable for patients who need long-term timed transdermal administration, such as insulin administration for diabetic patients.

Description

technical field [0001] The invention belongs to the field of medical technology, and relates to a long-course easy transdermal painless drug delivery device, which helps patients who need long-term injections to relieve pain. Background technique [0002] Diabetes is currently an incurable disease of human physiological dysfunction in the world. It not only seriously affects the normal life of patients, but also causes more than 80 kinds of acute or Chronic complications lead to serious consequences such as blindness, memory loss, cerebral palsy, gum and lower limb skin ulceration, lower limb nerve necrosis, paralysis, sexual dysfunction and loss, glomerulosclerosis, arteriosclerosis, heart disease, and even death. The latest research shows that there are currently hundreds of millions of patients with this type of disease worldwide, and the number of such patients in my country alone has exceeded 92 million, and the number of patients is still increasing rapidly at a rate o...

AI Technical Summary

Problems solved by technology

The current microneedle drug application technology can be roughly divided into two types: minimally invasive transdermal drug penetration and embedded needle drug application. The pores penetrate subcutaneously; due to the defense and self-repair function of the human skin, the minimally invasive corneum can heal quickly, which can effectively prevent the invasion of external microorganisms, but on the other hand, it also hinders the subcutaneous administration of macromolecular drugs through minimally invasive channels. Therefore, this type of minimally invasive transdermal drug penetration method has problems such as short curative effect, incomplete drug penetration, and large drug waste.

For the latter, most of the microneedles that contain the drug solution or communicate with the drug sac are embedded, and the drug is permeated subcutaneously through the microneedle channel. Although they are not confused by the problem of minimally invasive healing of the cornea, this type of system There are problems such as allergic reaction of the subcutaneous tissue to the embedded microneedles, slow penetration of the drug, and uneven drug administration.

[0005] The newly released microelectronic control intelligent drug delivery technology adopts a drug delivery system integrated with microelectronic control and microneedle drug delivery components. However, there are still problems of subcutaneous tissue allergy to long-term embedded microneedles. In addition, the design of microelectronic drug delivery control components used in the system is complicated, the production cost is high, and it is included with the patch. The mission ends when all the medicines are used up, which not only causes a lot of waste and pollution problems, but also greatly increases the production cost and use cost of the medicine patch, which makes the general consumers daunted

In addition, this type of drug infusion device undoubtedly brings a lot of inconvenience to patients' daily activities.

[0006] In addition, it should be pointed out that almost all insulin subcutaneous delivery methods (including microneedle delivery technology) on the market use insulin solution. Since insulin is unstable in solution and easy to degrade, strict aseptic and anaerobic packaging is required. At the same time, it must be stored at low temperature, which undoubtedly brings great restrictions to the demand for long-term use of the microneedle patch at body temperature.

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