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Leaves extract of panax sp., a process of making the same and uses thereof

A leaf extract, Panax genus technology, applied in the field of Panax genus plant leaf extract, its preparation and its application, can solve the problems of side effects, damage to health, etc., achieve human safety, improve physical strength and exercise ability, and increase exercise performance time Effect

Inactive Publication Date: 2011-04-06
株式会社优力竟
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0012] Also, while supplements including compounds like steroids, caffeine, sodium bicarbonate, sodium citrate etc. can significantly improve exercise performance, their excessive intake can cause deadly side effects and ultimately damage our health

Method used

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  • Leaves extract of panax sp., a process of making the same and uses thereof
  • Leaves extract of panax sp., a process of making the same and uses thereof
  • Leaves extract of panax sp., a process of making the same and uses thereof

Examples

Experimental program
Comparison scheme
Effect test

experiment example 1

[0133] Experimental Example 1: Preliminary Steps

[0134] (1) Purchase, quarantine and domestication of test animals

[0135] 7-week-old SD rats were purchased, and all rats were subjected to veterinary quarantine to observe their overall condition. The rats were acclimated in the experimental environment for about 7 days to select suitable and healthy test rats. During the experiment, the test animals were housed at a temperature of 22±2° C., a relative humidity of 50±20%, and conditions of 12 hours / day / night.

[0136] (2) Selection and grouping of animals for testing

[0137] Prior to grouping, acclimated rats were exercised on a treadmill in order to select healthy rats with no motor problems and average motor performance. Randomization was performed based on body weight after excluding unqualified rats.

[0138] (3) mark

[0139] The home cages were marked with identification cards including test number, sex, group number, individual identification number, dose, exper...

Embodiment 1

[0173] Example 1: Improvement of sports performance

[0174] (1) Method

[0175] 1) Administration of test samples

[0176] The energy-improving effect was evaluated by measuring exercise performance in a treadmill, and the test materials, negative control (0.5% Tween 20), UG0714 (ginseng root extract, positive control) and test materials 1 to 3 (UG0407, UG0507 and UG0712) were administered to rats.

[0177] 2) Determination

[0178] A. Observation of overall symptoms: The overall symptoms were observed once a day during the daily administration of the test materials, and during the observation period, whether the rats died or not was checked once a day.

[0179] B. Measurement of body weight: Body weight of rats was measured at the time of grouping, immediately before the administration of the test material and every week after the start of administration.

[0180] C. Determination of exercise and maximal exercise capacity of the non-exercise group: the test materials wer...

Embodiment 2

[0195] Example 2. Determination of anti-fatigue markers

[0196]In order to study the anti-stress effect of the test material on exercise stress by determining the maximum running distance of long-term and exhaustive exercise, anti-fatigue markers were determined in the blood of the exercise and non-exercise groups before and after the determination of the maximum running distance things. For this, blood samples were collected from the jugular vein 1 day before and within 20 min after the maximal exercise test. Creatine kinase (CK) and LDH (lactate dehydrogenase) were measured using a biochemical hematology analyzer (Hitachi 7080, Japan). Creatine was determined by using QuantiChrom's creatine assay kit (DICT-500). The absorbance of LDH related to anaerobic oxidation capacity was measured at 37° C. by using a spectrophotometer, and all measured values ​​are expressed in units of Umol / min / g.

[0197] In addition, by using AssayMax corticosterone ELISA kit (Gentaur, Lot No. E...

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Abstract

The present invention relates to a composition for improvement of exercise performance, fatigue recovery or prevention of oxidation response comprising Panax species plant leaves extract or processed product of the leaves extract, or mixture of the both as an active ingredient. The present composition comprising Panax species plant leaves extract or processed product of the leaves extract, or mixture of the both increases the exercise performance, inhibit the accumulation of fatigue markers in blood and prevents oxidation response, and thus is useful to improve physical strength and exercise capacity.

Description

technical field [0001] This study was supported by funding from the Plant Diversity Research Center of the 21st Century Frontier Research Program funded by the Ministry of Science and Technology of Korean Government (No. #PF0321204 -00) support. [0002] The present invention relates to compositions comprising Panax genus leaf extract or processed Panax genus leaf extract or a mixture of both as active ingredient for improving sports performance, fatigue recovery and preventing oxidative response. Background technique [0003] Typically, if a muscle is inactive for long periods of time, its function declines with age, and muscle volume and neuromuscular junctions (motor units) decrease, leading to fatigue, weakness, and decreased vitality, and ultimately to a markedly worse quality of life (Dohergy TJ, J Appl. Physiol., 95:1717-1727, 2003; Eric E et al., Physiol. Behav., 92(1-2):129-135, 2007). [0004] To prevent such problems, appropriate exercise such as continuous endu...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/258
CPCA61K36/258A61P3/02A61P21/00A61P39/06A61K2300/00
Inventor 禹盛植金东善都善吉李映撤金种汉成秀庆
Owner 株式会社优力竟
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