Veterinary yeast glucan injection
A technology for yeast glucan and injection, which can be applied in medical preparations containing active ingredients, drug delivery, antibacterial drugs, etc., and can solve problems that have not yet been seen.
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Embodiment 1
[0087] Add 99% n-propanol into the beaker and put it in a constant temperature water bath whose temperature drops to -15°C. When the temperature drops to -15°C, slowly drop the same amount of concentrated sulfuric acid into n-propanol with an acid burette , stirred while dropping, fully mixed, and prepared into a sulfonation reaction liquid. Add yeast dextran to the above reaction solution and react at -15°C for 2 hours. Immediately after the reaction, centrifuge at -10°C and 14000r / min for 12min to remove the reaction solution. The precipitate was washed with pre-cooled n-propanol for 3 times, then dissolved in deionized water, centrifuged to remove the unreacted yeast dextran precipitate, and the supernatant was collected and freeze-dried to obtain white powder sulfated yeast Dextran. Determined by the phenol-sulfuric acid method, the color of the sample is orange-yellow, indicating that the sulfated yeast glucan obtained above is sulfated dextran; judging according to the...
Embodiment 2
[0089] Carboxymethyl water-soluble yeast dextran 2g, sterilized and dissolved in 97ml of water for injection, subpackaged and sealed is the injection.
Embodiment 3
[0091] Carboxymethyl water-soluble yeast dextran 4g, dissolved in 96ml of water for injection after sterilization, sub-packaged and sealed is the injection.
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