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Traditional Chinese medicine composition for treating renal colic with upper urinary calculi

A technology of urinary calculus and composition, which is applied in the field of traditional Chinese medicine composition for treating upper urinary tract calculus combined with renal colic, can solve the problems of poor stone expulsion effect, and achieve the effect of remarkable effect, specific effect and simple compatibility

Inactive Publication Date: 2012-04-25
单海涛
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The amount of money grass in the prescription is often less than 30g, and the effect of stone removal is even worse.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0015] Take 60g of desmodium, 30g of peony, and 10g of licorice, mix and grind them and decoct twice (the amount of water is 10 times and 6 times the amount of medicinal materials respectively; soak for 0.5h, decoct for 1h and 0.5h respectively), filter and combine the filtrates, and extract them together The extract was concentrated to a specific gravity of 1.08, and then 95% ethanol was added to make the ethanol concentration of the extract reach 75%, left to stand for 24 hours, centrifuged, and the supernatant concentrated to a specific gravity of 1.15 to obtain an extract for subsequent use. Add 300g of starch and 300g of sucrose powder, add 1% hydroxypropylmethyl, cellulose solution, granulate with a one-step granulator, dry, add hydroxypropylmethyl, 5g of cellulose sodium, 10g of stearic acid, mix well, and press into tablets. Instantly.

Embodiment 2

[0017] Take 90g of desmodium, 45g of peony, and 15g of licorice, mix and grind them and decoct twice (the amount of water is 10 times and 6 times the amount of medicinal materials respectively; soak for 0.5h, decoct for 1h and 0.5h respectively), filter and combine the filtrates, and extract them together Liquid, the extract was concentrated to a specific gravity of 1.08, and then 95% ethanol was added to make the ethanol concentration of the extract reach 75%, left to stand for 24 hours, centrifuged, the supernatant was concentrated to a specific gravity of 1.20 extract, and set aside.

[0018] To make a soft board, dissolve 100g of dry gelatin in water, add 200g of glycerin, heat to make a soft board, put the above liquid medicine between two soft boards, roll it into a soft capsule with an automatic rotary encapsulation machine, and put it in liquid paraffin Cool and wash off the paraffin with ethanol.

Embodiment 3

[0020] Take 90g of desmodium, 45g of peony, and 15g of licorice, mix and grind them and decoct twice (the amount of water is 10 times and 6 times the amount of medicinal materials respectively; soak for 0.5h, decoct for 1h and 0.5h respectively), filter and combine the filtrates, and extract them together The extract was concentrated to a specific gravity of 1.08, and 95% ethanol was added to the extract to make the ethanol concentration 65%, left to stand for 24 hours, centrifuged, the filtrate was concentrated, dried and crushed, and set aside.

[0021] Mix the dry powder of the above extract with borneol, add 300g of starch and 200g of lactose, make a soft material with 3% dextrin solution, pass through an 18-mesh sieve to make granules, and dry at 500-600°C for 30 minutes. Add 20g of talcum powder, pack into capsules, and get ready.

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PUM

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Abstract

The invention discloses a traditional Chinese medicine composition for treating renal colic with upper urinary calculi, which is prepared from lysimachia, peony and liquorice as main raw materials and pharmaceutically acceptable adjuvants, wherein the mass ratio of the main raw materials lysimachia to peony to liquorice is (6-12):(3-6):1. Proven by pharmacologic experiments, the traditional Chinese medicine composition disclosed by the invention has notable curative effects on renal colic with upper urinary calculi.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for treating upper urinary calculi combined with renal colic. Background technique [0002] Upper urinary tract stones include kidney stones and ureteral stones. The occurrence of renal colic during upper urinary tract calculus expulsion is due to spasm of ureteral smooth muscle, resulting in tonic contraction. Not only will it cause unbearable pain, but it will also increase the resistance of the stone to move down. However, excessive relaxation of ureteral smooth muscle is not conducive to the downward movement of stones. [0003] Like other smooth muscles, ureteral smooth muscle contraction is also divided into tonic contraction and phasic contraction. Just as vasoconstriction causes blood pressure to rise, tonic contraction plays a very important role in maintaining the pressure in the lumen, but excessive tonic contraction can lead to smooth muscle spasm, and for patients with ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/71A61P13/04A61P13/12
Inventor 单海涛
Owner 单海涛
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