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Composition with functions of relieving physical fatigue and improving memory as well as preparation method and application thereof

A technology for relieving physical fatigue and improving memory. It is used in medical preparations containing active ingredients, food preparation, and drug combinations. It can solve problems such as decreased exercise capacity, inability to concentrate, and inability to relieve physical fatigue.

Active Publication Date: 2011-08-17
上海东锦食品集团有限公司 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] ① Poor memory, inattention, and decreased learning ability;
[0006] ② Muscle pain, decreased exercise ability, and physical fatigue that cannot be relieved after rest

Method used

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  • Composition with functions of relieving physical fatigue and improving memory as well as preparation method and application thereof
  • Composition with functions of relieving physical fatigue and improving memory as well as preparation method and application thereof
  • Composition with functions of relieving physical fatigue and improving memory as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1-3

[0095] Compositions 1-3

[0096]

[0097] Various components were mixed according to the above formula to obtain composition A, composition B and composition C respectively.

[0098] The preparation method of guarana extract is:

[0099] 1. Guarana seeds are reflux extracted with 6-10 times the amount of 90% ethanol for 3 times, each time for 3 hours;

[0100] 2. Filtrate, combine the filtrates, recover ethanol under reduced pressure, concentrate under reduced pressure to 60°C to obtain extract;

[0101] 3. Spray-dry the extract (the temperature of the air inlet is 150-180° C., and the temperature of the outlet air is 60-90° C.) to obtain a spray-dried fine powder.

[0102] After testing (testing method: Determination of caffeine in GB / T 5009.139-2003 beverages), based on the total weight of the obtained guarana extract, the caffeine content is 10-12%. .

[0103] The preparation method of American ginseng extract is:

[0104] 1. Pre-treatment of American ginseng: Clean...

Embodiment 4

[0116] safety test

[0117] Experimental animals: 20 Kunming mice, half male and half male, body weight: 18-22 g, provided by Shanghai Experimental Animal Center, Chinese Academy of Sciences. Production license number: SCXK (Shanghai) 2002-0010, experimental animal breeding room temperature 20-25 ℃, relative humidity 40-70%. Experimental animal license number: SCXK (Shanghai) 2002-0006. Animal feed was provided by Suzhou Shuangshi Experimental Animal Feed Technology Service Co., Ltd., registration number: Su E Si Sheng Zi (2002) 06.

[0118] experimental method:

[0119] (1) Test sample preparation: The daily recommended dose of this product is the total weight of each component of the composition 3 formula in Examples 1-3. Add distilled water to composition 3 to 20ml, mix well and serve as the test sample sample.

[0120] (2) Test method: Toxicological safety evaluation is carried out through mouse acute oral toxicity test, mouse bone marrow polychromatic erythrocyte micr...

Embodiment 5

[0128] Anti-fatigue function test

[0129] Experimental animals: Kunming white mice, license number: SCXK (Shanghai) 2002-0010, weighing 18-22 grams, female, clean animals provided by the Shanghai Experimental Animal Center of the Chinese Academy of Sciences (raised in the SPF animal room of this site). Experimental animal breeding room temperature 20-25 ℃, relative humidity 40-70%, experimental animal license number: SCXK (Shanghai) 2002-0006, animal feed, provided by Suzhou Shuangshi Experimental Animal Feed Technology Service Co., Ltd., registration certificate No.: Su E Shi Sheng Zi (2002) 06.

[0130] experimental method:

[0131] (1) Dosage design: In this experiment, three dosage groups of composition 1, composition 2 and composition 3 were set up, and distilled water blank control group and 5.6% sugar control group were also set up.

[0132] (2) Sample treatment: add distilled water to the composition to make up to 20ml, mix well and use it as a test sample.

[0133...

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Abstract

The invention discloses a composition with functions of relieving physical fatigue and improving memory as well as a preparation method and application thereof. The composition contains the following components in parts by weight: 5-60 parts of guarana extract, 60-600 parts of taurine, 0.3-8 parts of L-isoleucine, 0.1-2 parts of L-leucine, 0.2-5 parts of L-valine, 5-60 parts of L-alanine, 5-60 parts of glycine, 0.3-8 parts of L-lysine hydrochloride and 1-20 parts of American ginseng extract.

Description

technical field [0001] The invention relates to the field of compositions with health care functions, in particular to a composition with the functions of relieving physical fatigue and improving memory, its preparation method and application. Background technique [0002] Learning and memory are advanced functions of the brain, and at the same time learning and memory are two closely related neural processes. In short, learning is the neural process by which external information enters the brain, while memory is the storage and "reading" of information. Both learning and memory are brain activities based on conditioned reflexes, and the two complement each other and are inseparable. Learning and memory is an extremely complex physiological and biochemical process, divided into instantaneous, short-term and long-term. Instantaneous memory signals disappear within a second and are controlled by a small number of local neural area nuclei in the brain. Short-term memory is m...

Claims

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Application Information

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IPC IPC(8): A23L1/30A23L1/305A61K36/77A61P39/00A61P25/00A61K31/185A61K31/198
Inventor 蔡愈杭陈伟何会罗殷
Owner 上海东锦食品集团有限公司
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