Immunologic stimulant oral syrup and preparation method thereof
A technology of immunostimulants and syrups, which is applied in the field of immunostimulants oral syrups and its production, and can solve problems such as difficult quality control, low bioavailability, and inconvenient use
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no. 1 example
[0062] The immunostimulant oral syrup is made of the following raw materials in parts by weight per 100 ml: pidotimod, 2-8g; sucrose, 35-65g; pH regulator, 0.5-1.5g; ethylparaben, 0.02~0.06g; ethanol, 0.6~1.8g; essence, 0.01~0.08g, the balance is purified water.
[0063] In order to achieve a better effect, every 100ml of the oral syrup of immunostimulants can be made of the following raw materials in parts by weight: pidotimod, 3-5g; sucrose, 40-55g; pH regulator, 0.6-1.2 g; ethylparaben, 0.03-0.05g; ethanol, 0.9-1.3g; essence, 0.012-0.03g, and the balance is purified water.
[0064] Above-mentioned pH adjusting agent is any one in anhydrous sodium carbonate, sodium carbonate, sodium hydroxide and sodium bicarbonate.
[0065] The above-mentioned essence is any one of ethyl maltol, lemon essence, banana essence, grapefruit essence and orange essence.
[0066] In this embodiment, every 100 ml of the immunostimulant oral syrup is made of the following raw materials in parts by...
no. 2 example
[0073] In this example, every 100 milliliters of the drug is made of the following raw materials in parts by weight: pidotimod, 4 g; sucrose, 45 g; anhydrous sodium carbonate, 0.9-1.2 g; ethylparaben, 0.04 g; ethanol , 1.0g; grapefruit essence, 0.02g; the balance is purified water.
[0074] Production includes the following steps:
[0075] Step 1): First, weigh each raw material according to the above-mentioned parts by weight; then add sucrose into 20 ml of purified water, stir and heat until boiling, so that the sucrose is completely dissolved into syrup, cool to below 60°C, and filter for later use;
[0076] Step 2): Anhydrous sodium carbonate is made into a 1mol / L solution with purified water, and the solution is used for subsequent use;
[0077] Step 3): adding ethylparaben to ethanol, fully stirring to completely dissolve the ethylparaben to obtain a solution, and set the solution for later use;
[0078] Step 4): first add pidotimod into 20 ml of purified water, heat a...
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