Chinese-medicinal compound lotion for treating dermatitis eczema

A technology of compound lotion and dermatitis eczema, which is applied in the field of medicine, can solve the problems of gastrointestinal irritation, inhibition, and high blood drug concentration, and achieve the effects of avoiding gastrointestinal irritation, reducing inhibition, and improving compliance

Inactive Publication Date: 2011-10-05
SECOND MILITARY MEDICAL UNIV OF THE PEOPLES LIBERATION ARMY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, oral administration not only stimulates the gastrointestinal tract, but also has certain side effects due to the high blood concentration of the whole body, such as the inhibitory effect on the central nervous system.
So far, there is no report of treating skin eczema with traditional Chinese medicine compound lotion

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] Embodiment 1 prepares Chinese medicine compound lotion

[0024] 1. Prepare extracts of Sophora flavescens, Fructus Cnidii, Phellodendron Phellodendri extract:

[0025] Take 60g of Sophora flavescens, 50g of Fructus Cnidii, and 30g of Phellodendron Phellodendri, add 8 times the weight of the medicinal materials in 70% ethanol for reflux extraction for 1.5 hours, filter, and collect the filtrate; then add 70% ethanol in the amount of 6 times the weight of the medicinal materials for reflux extraction for 1 hour , filter, collect the filtrate, combine the two filtrates, reclaim ethanol, obtain the medicinal extract of solution volume: medicinal material weight=1:1;

[0026] 2. Preparation of Chinese angelica, Chuanxiong, and rhubarb extracts:

[0027] Take 30g of Angelica sinensis, 20g of Rhizoma Chuanxiong, and 20g of rhubarb, add 10 times the weight of the medicinal material to decoct for 1 hour, filter, and collect the filtrate; then add 8 times the weight of the medic...

Embodiment 2

[0030] Embodiment 2 prepares Chinese medicine compound lotion

[0031] 1. Prepare extracts of Sophora flavescens, Fructus Cnidii, Phellodendron Phellodendri extract:

[0032] Take 70g of Sophora flavescens, 60g of Fructus Cnidii, and 40g of Phellodendron Phellodendri, add 8 times the weight of the medicinal materials in 70% ethanol for reflux extraction for 1.5 hours, filter, and collect the filtrate; then add 70% ethanol in the amount of 6 times the weight of the medicinal materials for reflux extraction for 1 hour , filter, collect the filtrate, combine the two filtrates, reclaim ethanol, obtain the medicinal extract of solution volume: medicinal material weight=1:1;

[0033] 2. Preparation of Chinese angelica, Chuanxiong and rhubarb extracts:

[0034] Take 35g of Angelica sinensis, 25g of Rhizoma Chuanxiong, and 30g of rhubarb, add 10 times the weight of the medicinal materials to decoct for 1 hour, filter, and collect the filtrate; then add 8 times the weight of the medic...

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PUM

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Abstract

The invention, relating to the technical field of medicine, provides a Chinese-medicinal compound lotion for treating dermatitis eczema and a preparation method thereof. The component proportion of the lotion is: 50-70g of sophora flavescens, 40-60g of common cnidium fruit, 20-40g of phellodendron, 25-35g of Chinese angelica, 15-25g of Ligusticum wallichii, 15-30g of rheum officinale, 3-6g of borneol, and 0.1wt% of antiseptic ethylparaben. The preparation method comprises the following steps: 1) preparing an extract of sophora flavescens, common cnidium fruit and phellodendron; 2) preparing an extract of Chinese angelica, Ligusticum wallichii and rheum officinale; 3) mixing the extracts obtained by step 1) and 2), adding borneol according to the proportion and 0.1wt% of antiseptic ethylparaben, adding water until the amount of the mixture reaches to 1000ml for dilution, and sub-packaging. The lotion can avoid the irritation on gastrointestinal tracts by oral administration, reduce the blood concentration of body and reduce side effects through the transdermal drug delivery. The preparation method is simple, and the lotion is easy to operate and improves the compliance of medicine. The invention provides a novel medicinal preparation for treating dermatitis eczema.

Description

technical field [0001] The invention relates to the technical field of medicine, and relates to a traditional Chinese medicine compound lotion for resisting dermatitis and eczema and a preparation method thereof. Background technique [0002] Eczema is a common allergic inflammatory skin disease, which is named after the tendency of oozing moisture from the rash lesions. Its clinical manifestations are characterized by diverse, symmetrical distribution of rashes, severe itching and recurrent attacks, and easy to become chronic. The disease can occur at any age, in any part, and in any season, but often recurs or aggravates in winter. The etiology and pathogenesis of eczema are quite complicated, involving multiple factors inside and outside the body. In recent years, with the aggravation of environmental pollution, the abuse of chemicals, the accelerated pace of social life, and increased mental stress, the incidence of eczema has been increasing year by year. Although th...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/756A61K9/00A61P17/00A61P37/08A61K31/045
Inventor 王峰吴建华刘继勇王季尧汪五清尤本明
Owner SECOND MILITARY MEDICAL UNIV OF THE PEOPLES LIBERATION ARMY
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