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Medicinal composition for treating burn and scald and preparation method thereof

A composition and a technology for burns and scalds are applied to a pharmaceutical composition for the treatment of burns and scalds. The preparation field of the pharmaceutical composition can solve the problems that the skin grafting technology cannot be widely and effectively carried out, the external medicine cannot obtain satisfactory curative effects, and the work intensity of medical staff is high, etc. problems, to achieve the effect of protecting pain nerve endings, rich blood circulation, and no allergy phenomenon

Active Publication Date: 2013-04-10
彭卫新
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Jingwanhong ointment is an old brand product of Tianjin Darentang Pharmaceutical No. 2 Factory. Its main ingredients are: Burnet, gardenia, rhubarb, myrrh, borneol, etc. It has a good curative effect on burns, but the disadvantage is that it is easy to leave scars after a long course of treatment
The main ingredients of MEBO are Scutellaria baicalensis, Coptis chinensis, etc. The dressing should be changed every four hours, and the seriously injured patients need to change the dressing every two hours. The work intensity of medical staff is high, and the treatment time is long, so the effect on severe burns is not significant
Burning Spirit Tincture is a product of Shijiazhuang Lerentang. It is irritating to a certain extent and has the disadvantage of causing short-term pain to the wound when it is applied.
Silver sulfadiazine has the advantage of strong antibacterial effect, but this drug has produced drug-resistant strains, and the wound infection tends to increase gradually; due to the local dryness of the wound during application, wound deepening may occur in superficial second-degree burns or deep second-degree burns It is also irritating to a certain extent, and there is pain after drying. It is difficult for bandage therapy to change the wound, and the wound is prone to bleeding and pain, which makes the patient more painful; silver sulfadiazine can cause sulfa crystalluria and leukopenia, and those who are allergic to sulfa, Patients with impaired liver and kidney function and newborns are contraindicated
The treatment of severe burns often requires skin grafting. Although skin grafting technology has reduced the mortality rate of burn patients, the huge trauma caused by the treatment and the quality of life after healing are unsatisfactory. Multiple plastic surgeries and huge medical expenses are the fundamental reasons why skin grafting technology cannot be carried out widely and effectively
The traditional drying therapy is to keep the wound dry, inhibit bacterial reproduction, and use a large amount of antibiotics and anesthetics. The cycle is long and scars are easy to leave
Moreover, the current use of external medicine is only part of the treatment of burns and scalds. In actual application, it needs to be combined with surgery and other auxiliary means (such as infiltration, wet compress, infrared radiation, dressing exchange, etc.) and systemic treatment. Still can't get satisfactory effect

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] 1. First clean 10g Scutellaria barbata, 15g Polygonum cuspidatum, 10g Zizhucao, 10g Baiji, 13g Burnet, and 27g Rhubarb, and dry them with a Chinese herbal medicine dryer, using the heat pump drying method. The temperature of the hot air is based on the material to be dried The quantity, water content, heat resistance, properties, etc., the thickness of the material does not exceed 8CM, select the appropriate temperature of 90 ℃, set the drying time for 150 minutes, after drying, pick out the impurities, scorch, and the shape of the material, Keep the medicinal materials with good color, shape and sensory properties, and then use a pulverizer one by one to crush them into the finest powder and pass through a 100-mesh sieve, collect them separately, weigh them in proportion and set aside.

[0031] 2. Weigh 15g of comfrey, pulverize comfrey into coarse powder and pass through a 50-mesh sieve, add 90g of sesame oil to soak, stir twice a day, soak for seven days, when the ses...

Embodiment 2

[0034] 1. First clean 10g Scutellaria barbata, 15g Polygonum cuspidatum, 10g Zizhucao, 10g Baiji, 13g Burnet, and 27g Rhubarb, and dry them with a Chinese herbal medicine dryer, using the heat pump drying method. The temperature of the hot air is based on the material to be dried The quantity, water content, heat resistance, properties, etc., the thickness of the material does not exceed 8CM, select the appropriate temperature of 120 ℃, set the drying time for 60 minutes, after drying, pick out the impurities, scorch, and the shape of the material, Keep the medicinal materials with good color, shape and sensory properties, and then use a pulverizer one by one to crush them into the finest powder and pass through a 100-mesh sieve, collect them separately, weigh them in proportion and set aside.

[0035] 2. Weigh 15g of comfrey, pulverize comfrey into coarse powder and pass through a 50-mesh sieve, add 120g of sesame oil to soak, stir twice a day, soak for seven days, when the se...

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PUM

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Abstract

The invention discloses a medicinal composition for treating burn and scald. The medicinal composition comprises the following bulk drugs in percentage by weight: 13 percent of garden burnet, 10 percent of rhizoma bletillae, 10 percent of callicarpa undiflora, 27 percent of rhubarb, 15 percent of giant knotweed, 10 percent of barbed skullcap herb and 15 percent of gromwell root, wherein the medicaments are settled and crushed into fine powder and then uniformly mixed to obtain a mixture; the mixture is immersed in sesame oil in a ratio of 1:(6-8) to obtain a second mixture; and the second mixture is sieved to filter off residues and is bottled for later use. The medicinal composition has the advantages of powerful anti-infection, pain relieving and impervious functions, no irritation to a wound surface, capability of promoting repairing and healing of the wound surface of a cut, locally flat healed wound surface, no scar on the healed wound surface of the first, second and third degree burns and scalds, short treatment period, no irritation phenomenon, no toxic or side effect, low treatment cost, convenience in operation, easiness in change of a medical prescription and convenience in nursing. The medicinal composition can be used for reducing and treating hypertrophic scar of deep second degree burn and superficial third degree burn, promoting the healing of the wound surface and is an external pure traditional Chinese medicine for treating the burn and scald without being limit by medical conditions during operation and implementation.

Description

technical field [0001] The invention relates to an externally used medicine for healing burns and scalds, in particular to a medicine composition for treating burns and scalds prepared from Chinese herbal medicines, and also relates to a preparation method of the medicine composition. Background technique [0002] Burns and scalds are very common in life, work or war. They are usually damage to skin or mucous membrane tissue caused by heat (including hot liquid, steam, high temperature gas, flame, electric energy, chemical substances, hot metal liquid or solid, etc.) . The degree of burn and scald is different by the height of temperature, the length of action time, and its severity depends on the scope and depth of injured tissue, can be divided into I degree, II degree and III degree with burn degree. The treatment time of burn patients is long, the complications are many, and the disability rate is high, especially the deep burns between the face and neck often lead to s...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/898A61P17/02
Inventor 彭卫新
Owner 彭卫新
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