A traditional Chinese medicine composition for preventing and treating osteoporosis and its preparation method

A technology of osteoporosis and composition, which is applied in the field of traditional Chinese medicine composition, can solve problems such as regulating the function of minerals in the body, and achieve the effect of preventing and treating osteoporosis

Active Publication Date: 2011-12-21
JINAN UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Chinese Invention Patent Publication No. CN1568965A discloses "a drug for treating osteoporosis and its preparation method", which is mainly made of soybean total flavonoids and epimedium total flavonoids. The drug has estrogen-like effects and kidney-tonifying and bone-strengthening effects Achieving a therapeutic effect, but not mentioning the regulation of mineral action in the body

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] 1. Take each raw material according to the following weight ratio: 100 grams of Digongteng, 50 grams of Qiannianjian, 50 grams of Star Anise and 80 grams of Aesculus for subsequent use;

[0019] 2. Add 9 times the amount of water to soak Dinggongteng, Qiannianjian, Star Anise and Aescinus in the above weight ratio for 2 hours, heat and decoct, filter after boiling, add 8 times the amount of water to the dregs, heat to boil, and filter after boiling , the filtrates were combined, and the solids were separated in a high-speed centrifuge to obtain a supernatant;

[0020] 3. When the supernatant is concentrated to a relative density of 1.05, it enters the spray dryer, the inlet air temperature is controlled at 140°C, the outlet air temperature is 100°C, the rotation speed of the atomizer is 50 rpm, and the feed rate is 3ml / min. 14 grams of dry powder; pulverize the spray-dried powder into fine powder, which is the traditional Chinese medicine composition of the present inve...

Embodiment 2

[0022] 1. Take by weighing each crude drug according to the following weight proportions: 300 grams of Dinggongteng, 150 grams of Qiannianjian, 150 grams of Star Anise and 200 grams of Aesculus Aesculus for subsequent use;

[0023] 2. Add 80 grams of Dinggongteng, Qiannianjian, Star Anise and Aesculus with 10 times the amount of water to soak for 3 hours, heat and decoct, filter after boiling, add 9 times the amount of water to the dregs, heat to boil, and boil After filtering, the filtrates are combined, and the solids are separated by a high-speed centrifuge to obtain a supernatant;

[0024] 3. When the supernatant is concentrated to a relative density of 1.06, it enters the spray dryer, the inlet air temperature is controlled at 160°C, the outlet air temperature is 110°C, the rotation speed of the atomizer is 60 rpm, and the feed rate is 5ml / min to obtain a spray-dried powder 40 grams; pulverized spray-dried powder into fine powder, which is the traditional Chinese medi...

Embodiment 3

[0026] 1 . Take by weighing each crude drug according to the following weight proportions: 200 grams of Dinggongteng, 100 grams of Qiannianjian, 100 grams of Star Anise and 150 grams of Aescinus are subsequent to use;

[0027] 2. Add 10 times the amount of water to soak Dinggongteng, Qiannianjian, Star Anise and Aescinus in the above weight ratio for 3 hours, heat and decoct, filter after boiling, add 9 times the amount of water to the dregs, heat to boil, and filter after boiling , the filtrates were combined, and the solids were separated in a high-speed centrifuge to obtain a supernatant;

[0028] 3. When the supernatant is concentrated to a relative density of 1.06, it enters the spray dryer, the inlet air temperature is controlled at 160°C, the outlet air temperature is 110°C, the atomizer rotates at 60 rpm, and the feed rate is 5ml / min to obtain a spray 26 grams of dry powder; pulverize spray-dried powder into fine powder.

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PUM

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Abstract

The invention discloses a traditional Chinese medicine composition for preventing and treating osteoporosis and a preparation method thereof. The traditional Chinese medicine composition for preventing and treating osteoporosis disclosed by the invention is prepared from the following components in parts by weight: 10-30 parts of Erycibe obtusifolia, 5-15 parts of homalomena rhizoma, 5-15 parts of truestar anisetree and 8-20 parts of schefflera arboricola. The traditional Chinese medicine composition disclosed by the invention can be used for preparing the drug dosage form for preventing or treating osteoporosis; and experiments prove that after using the drug prepared from the traditional Chinese medicine composition disclosed by the invention, the bone density as well as calcium and phosphorus contents in serum can be significantly increased.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine compositions, in particular to a traditional Chinese medicine composition for preventing and treating osteoporosis and a preparation method thereof. Background technique [0002] Osteoporosis is a common bone metabolic disease in the elderly. Currently, the age tends to be advanced, and it has become one of the international public health problems. Its pathogenesis has not been very clear, and it is generally believed that it is caused by hormone regulation (estrogen, parathyroid hormone, calcitonin and active vitamin D), nutritional status (calcium, phosphorus, protein and fat, etc.), physical factors (exercise) , sunlight), immune function and genetic changes are closely related. The present invention adopts Chinese medicinal materials as raw materials and forms a traditional Chinese medicine composition based on the theory of traditional Chinese medicine and modern research result...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/888A61P19/10
Inventor 蔡宇
Owner JINAN UNIVERSITY
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