Special solution for preventing skin lesion after chemotherapeutic drug exosmosis
A technology for skin damage and chemotherapeutic drugs, applied in skin diseases, drug combinations, active ingredients of heterocyclic compounds, etc., can solve the problems of patient pain, tissue necrosis, patient pain, etc.
Inactive Publication Date: 2012-07-18
李运智
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Problems solved by technology
Once these drugs leak into the subcutaneous tissue, it will cause damage to the subcutaneous tissue. In severe cases, it can cause tissue necrosis and ulceration, which not only causes great pain to the patient, delays treatment, and affects the prognosis of the patient.
In order to reduce or prevent the leakage of intravenous infusion of chemotherapy drugs, the nursing staff strictly implement the operating procedures, correctly select the injection site, strictly control the injection to effectively protect the vein, strictly follow the drug dispensing procedure according to the characteristics of the drug, and closely observe the infusion process. However, due to the long-term Intravenous injection increases vascular fragility; obese patients and elderly patients have poor vascular visibility, low vascular elasticity and blood flow velocity, and are prone to extravascular leakage of chemotherapy drugs; All kinds of puncture injuries are the main causes of drug leakage
Therefore, the leakage of chemotherapy drugs causes great pain to patients, and increases the cost of treatment for patients.
Method used
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Experimental program
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Effect test
Embodiment
[0007] Embodiment: 50% magnesium sulfate 160ml, 2% lidocaine 80ml, dexamethasone 10ml, 5% sodium bicarbonate 70ml, anisodamine 40ml, vitamin B 12 40ml and 600ml of 0.9% normal saline are mixed evenly, divided into 100ml / bag, sealed and sealed, sterilized, and labeled for later use.
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Abstract
The invention belongs to the technical field of medicine, and discloses a special solution for preventing skin lesion after chemotherapeutic drug exosmosis. Raw materials of the special solution include 50% magnesium sulfate, 2% lidocaine, dexamethasone, 5% sodium bicarbonate, anisodamine, vitamin B 12 and 0.9% saline solution. The raw materials are allocated proportionally according to different characteristics of each raw material; bottling the mixture respectively with 100ml in each bottle after even mixing; and the special solution is prepared after sealing, sterilization process and labeling. The special solution for preventing the skin lesion after the chemotherapeutic drug exosmosis has the advantages that the fading away of tissue edema is promoted, vessels are enabled to constrict so as to relieve the pain; vasospasm of patients can be eliminated, microcirculation can be improved, repair and regeneration of intestine epithelial cells and vascular endothelial cells of damaged skins are facilitated, cambium growth is accelerated; hair follicles, a sweat gland and subcutaneous tissues are repaired, chemotherapeutic drug absorption is reduced, medicine formation of a DNA compound can be prevented, toxic effects of exosmosis drugs are decreased, skin necrosis is prevented, and the skin is protected. According to the special solution, patients undergoing chemotherapy can receive the chemotherapy well, length of hospital stay is shortened, and pains and family burdens of the patients are reduced. The special solution has simple preparation, convenient operation, and low cost which is easy for the patients to accept. The total effective rate reaches 98% after clinical use on more than 150 chemotherapeutic exosmosis patients, and no special toxic or side effects appears.
Description
technical field [0001] The invention belongs to medicines, specifically a special solution for local continuous wet compress to prevent skin damage after extravasation of chemotherapeutic drugs. Background technique [0002] Leakage of chemotherapy drugs refers to the leakage or infiltration of chemotherapy drugs into the subcutaneous tissue during infusion. Once these drugs leak into the subcutaneous tissue, it will cause damage to the subcutaneous tissue, and in severe cases, it can cause tissue necrosis and ulceration, which not only causes great pain to the patient, delays treatment, and affects the patient's prognosis. In order to reduce or prevent the leakage of intravenous infusion of chemotherapy drugs, the nursing staff strictly implement the operating procedures, correctly select the injection site, strictly control the injection to effectively protect the vein, strictly follow the drug dispensing procedure according to the characteristics of the drug, and closely ...
Claims
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IPC IPC(8): A61K33/06A61P17/00A61K31/167A61K31/46A61K31/573A61K31/714A61K33/00
Inventor 李运智
Owner 李运智
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