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New uses of p-hydroxycinnamic acid

A technology of p-hydroxycinnamic acid and medicine, which is applied in the field of new application of p-hydroxycinnamic acid, can solve the problems of lack of vaccines, no reports of hydroxycinnamic acid drugs against livestock and poultry viruses or anti-bacterial diseases, etc., to ensure food safety Safety, solution to food antimicrobial residues, and the effect of improving competitiveness

Active Publication Date: 2011-12-28
CHINA AGRI UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] In 2005, the Ministry of Agriculture issued a document prohibiting the application of broad-spectrum drugs (viralin, amantadine, rimantadine, acyclovir) used by humans to livestock and poultry drugs to prevent the transfer of antiviral drug resistance from livestock to humans However, some infectious diseases in my country still lack effective vaccines to control (such as respiratory reproductive syndrome, porcine myocarditis, pig unknown high fever, etc.), so it is urgent to develop effective drugs to prevent these diseases
[0007] There is no report about the use of p-hydroxycinnamic acid drugs for anti-viral or anti-bacterial diseases in livestock and poultry

Method used

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  • New uses of p-hydroxycinnamic acid

Examples

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Comparison scheme
Effect test

Embodiment 1

[0025] Content of p-hydroxycinnamic acid in the present invention: p-hydroxycinnamic acid 25mg / ml. Its preparation process is as follows:

[0026] Weigh according to the above parts by weight, fully dissolve with 30% absolute ethanol, add 20% Tween-20 and 50% water, mix evenly, divide into bottles, and obtain an oral liquid preparation.

Embodiment 2

[0028] The content of p-hydroxycinnamic acid in the present invention: p-hydroxycinnamic acid 20mg / ml. Its preparation process is as follows:

[0029] Weigh according to the above parts by weight, fully dissolve with 30% absolute ethanol, add 20% Tween-20 and 50% water, mix evenly, divide into bottles, and obtain an oral liquid preparation.

Embodiment 3

[0031] The p-hydroxycinnamic acid content of the present invention: p-hydroxycinnamic acid 35mg / ml. Its preparation process is as follows:

[0032] Weigh according to the above parts by weight, fully dissolve with 30% absolute ethanol, add 20% Tween-20 and 50% water, mix evenly, divide into bottles, and obtain an oral liquid preparation.

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Abstract

The invention discloses new application of p-hydroxycinnamic acid to preparation of medicines for preventing and treating viral disease or bacterial disease of livestock and poultry. The product can prevent and treat viral disease or bacterial disease of livestock and poultry and can improve production performance of livestock and poultry. In vivo and in vitro tests show that the p-hydroxycinnamic acid can prevent and treat diseases caused by mycoplasma gallisepticum, bovine colibacillosis and the like. The in vivo test shows that the p-hydroxycinnamic acid can prevent and treat poultry bursafabricius viral disease, avian mycoplasmosis and bird flu H9 and H5 subtype virus infection.

Description

[0001] This application is a divisional application with an application date of February 8, 2010 and an application number of 201010109913.9. technical field [0002] The present invention relates to a new use of p-hydroxycinnamic acid, in particular to the application of p-hydroxycinnamic acid in the preparation of medicines for preventing and treating viral and bacterial diseases of livestock and poultry, especially for bursal disease, avian influenza, and Chronic Respiratory Disease. Background technique [0003] In recent years, as the safety of livestock products has attracted more and more attention from consumers, the production of pollution-free livestock products has become an inevitable trend in the development of animal husbandry. The registration and management of veterinary drugs in developed countries are becoming increasingly strict. The European Union announced in 2006 that antibiotics would no longer be used as production-promoting additives, and many veteri...

Claims

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Application Information

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IPC IPC(8): A61K31/192A61P31/04A61P31/12
CPCY02A40/70
Inventor 何润春何诚张发明李树梅欧长波
Owner CHINA AGRI UNIV
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