Collagen production enhancer, and external composition for skin and cosmetic each comprising same

A technology of external composition and accelerator, applied in the field of skin external composition and cosmetics, to achieve the effect of improving luster, easy acceptance, and suppressing manufacturing cost

Inactive Publication Date: 2012-05-16
COMBI CORP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, the extract used here is obtained by extracting the bird's nest with hot water and removing the solid content, and it is obviously different from the enzymatic hydrolyzate of bird's nest that is

Method used

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  • Collagen production enhancer, and external composition for skin and cosmetic each comprising same
  • Collagen production enhancer, and external composition for skin and cosmetic each comprising same
  • Collagen production enhancer, and external composition for skin and cosmetic each comprising same

Examples

Experimental program
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Embodiment

[0063] The present invention will be specifically described based on the following examples, but the present invention is not limited to these examples.

[0064] (1) Preparation of bird's nest samples

[0065] (1-1) Bird's nest enzymatic hydrolyzate 1

[0066] Commercially available unbleached bird's nest is pulverized with a pulverizer to obtain bird's nest powder with a 100-mesh pass (below particle size 150 μm), add about 50 times the amount (mass) of water to the bird's nest powder, and swell at 5°C for 20 hours, and then sterilized at 121°C for 15 minutes.

[0067] After cooling the obtained treatment solution, the pH was adjusted, and an enzyme containing protease (trade name "Pancleachin F", manufactured by Amano Pharmaceutical Co., Ltd.) was added in an amount of 2% by mass relative to the bird's nest powder, and reacted at 45° C. for 3 hours.

[0068] The enzyme reaction solution was adjusted to pH 7.0, then heated at 90° C. for 5 minutes to inactivate the enzym...

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Abstract

Disclosed is a collagen production enhancer, which comprises an enzymatically decomposed product of swallow's nest as an active ingredient. Specifically disclosed are: an excellent type-I collagen production enhancer which can be produced with high efficiency and is highly safe; and an external preparation and a cosmetic, each of which comprises the type-I collagen production enhancer.

Description

[0001] References to related applications [0002] This application is based on Japanese Patent Application No. 2009-148754 (filing date: June 23, 2009 ) filed earlier, and claims the benefit of priority thereof, and the entire disclosure content thereof is incorporated herein by reference. technical field [0003] The invention relates to a collagen production accelerator which uses bird's nest hydrolyzate as an active ingredient. More specifically, the present invention relates to a collagen production promoter that promotes the production of type I collagen in skin dermal fibroblasts. In addition, the present invention relates to a composition for external use on skin and cosmetics comprising an enzymatic hydrolyzate of bird's nest as an active ingredient thereof. Background technique [0004] Skin problems such as rough skin and / or wrinkles, sagging, and decreased elasticity of the skin are important concerns especially for women. These skin problems are generally thou...

Claims

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Application Information

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IPC IPC(8): A61K8/98A61Q19/00A61Q19/08A61K35/24A61K35/57A61P17/16
CPCA61Q19/08A61K8/981A61Q19/004A61P17/16
Inventor 武川和琴渡边卓巳
Owner COMBI CORP
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