Method and device for injury potential compensation after spinal cord injury

Abstract

The invention discloses a method and a device for injury potential compensation after spinal cord injury. The method comprises the following steps of: detecting an injury potential after spinal cord injury, observing the value of injury potential in real time, and controlling a stimulation voltage according to the observed value of injury potentials to allow the injury potential close to zero. The method achieves injury potential compensation to ensure that the spinal cord microenvironment is relatively stable. The device for implementing the compensation method comprises four stimulating electrodes, a stimulation voltage generating circuit (2), an injury potential measuring electrode, an injury potential amplifying circuit (4) and voltage display equipment (5). The stimulation voltage generating circuit (2) generates an adjustable stimulation voltage, the stimulation voltage is applied onto the spinal cord of a patient through the stimulating electrodes to stimulate the spinal cord, the injury potential measuring electrode is used for measuring an injury potential, the injury potential amplifying circuit (4) magnifies the injury potential and filters off high-frequency interference in the injury potential, the voltage display equipment (5) displays the value of magnified injury potential, and the stimulation voltage is regulated according to the value of magnified injury potential.

Description

technical field [0001] The invention relates to a treatment method and device for spinal cord injury, in particular to a damage potential compensation method and an electrical stimulator thereof. Background technique [0002] The reconstruction of motor and sensory function after spinal cord injury is one of the major challenges in neuroscience research, and many therapies are currently devoted to promoting the repair of injury. Since the mid-1980s, foreign scholars have successively reported that the application of electric field stimulation can promote the growth of nerve axons to the cathode, reduce the formation of glial scars after injury, and create a good environment for nerve regeneration after central nervous system injury. In order to achieve bidirectional growth of damaged nerves, oscillating electric field stimulation can be used, that is, the polarity of the electric field is exchanged at regular intervals. The current oscillating electric field stimulators mos...

AI Technical Summary

Problems solved by technology

Oscillating electric field stimulation has been used to treat spinal cord injury for more than 20 years. Although the first phase of clinical trials and a large number of animal experiments have shown that oscillating electric field stimulation can promote axon regeneration after spinal cord injury, the mechanism by which oscillating electric field stimulation promotes axon regeneration is still unknown. Unknown

In particular, there is no distinction between different degrees of injury and the time from the initial injury during implantation, and there is no basis for the selection of electrical stimulation parameters, which severely restricts the application of oscillating electric field stimulation in the treatment of spinal cord injuries.

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