4 results about "Oscillating electric field" patented technology

The present disclosure relates to methods, devices and systems for exposing microorganisms or compositions comprising functional proteins to an oscillating electric field substantially free of a magnetic component in order to improve stress responses, survival and metabolite or protein production. In embodiments, a controller drives one or more insulated emitters with a true AC signal or pulsed DC signal, in stepped, swept or shuffled patterns of an electric field oscillating at one or more frequencies in the range 210 Hz to 99 kHz. Exposure to the field provides surmounting energy that enhances protein breathing, catalysis, and fundamental functions of multiprotein complexes including transcription factors and ribosomes, thereby improving stress resistance of microorganisms, their viability during fermentation, drying, storage, transport, and / or increasing production of functional or therapeutic proteins, metabolites or microbial lysates. The technology is applicable to manufacture of probiotics, therapeutics, metabolites, food, alcohol, feed and bioenergy, cosmetics, nutraceuticals and biopharmaceuticals..

The invention relates to a supercritical anti-solvent-electrostatic spray coupling system which comprises a supercritical anti-solvent generation module, a material mixing module and an electrostatic atomization module which are sequentially connected through a connecting pipeline, and a time-space synchronization control module which is in communication connection with the supercritical anti-solvent generation module and the electrostatic atomization module. The space-time synchronous control module cooperatively controls the oscillating electric field and the pressure of the supercritical anti-solvent, so that the electric field jet breaking of the material is realized by the electric field force, and the absolute value of the difference value between the Taylor cone forming time and the supercritical anti-solvent diffusion time is controlled within a set range, so that the supercritical anti-solvent permeates into liquid drops within a millisecond-level time scale; the invention discloses a preparation method of brain-targeted nano-particles, which comprises the following steps: dissolving a solvent in a solvent to trigger a sudden drop effect of polarity of the solvent, so that solute is instantaneously crystallized, and finally a nano-suspension with a particle size of less than 200nm and uniform particle size distribution (PDilt: 0.2) is formed, is suitable for preparing brain-targeted nano-particles with high drug loading capacity and small particle size, and can effectively cross a blood-brain barrier (BBB) to realize continuous and green production.

A method of reducing the magnitude of a quasi-static electric dipole field at the null position of an oscillating electric quadrupole field of an ion trap, comprising: trapping at least one ion in a t

A method of reducing the magnitude of a quasi-static electric dipole field at the null position of an oscillating electric quadrupole field of an ion trap, comprising: trapping at least one ion in a t