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Toothpaste for preventing and treating recurrent aphtha and preparation method

A technology for recurrent aphtha and toothpaste, applied in the field of daily necessities, can solve problems such as recurrent aphthous ulcers that cannot be cured, strong irritation of the digestive tract, and oral discomfort, and achieve high-efficiency prevention and treatment, no drug resistance, and no environmental pollution Effect

Inactive Publication Date: 2013-04-10
CHANGSHU HUAGANG PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although the above-mentioned existing Chinese patent medicines for the treatment of recurrent aphtha can temporarily relieve symptoms, they also cause discomfort in the mouth and cannot radically cure recurrent aphtha.

Method used

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  • Toothpaste for preventing and treating recurrent aphtha and preparation method
  • Toothpaste for preventing and treating recurrent aphtha and preparation method
  • Toothpaste for preventing and treating recurrent aphtha and preparation method

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0059] The present invention also provides a preparation method of toothpaste for preventing and treating recurrent aphthous ulcers, which comprises:

[0060] The first step is to prepare the Chinese medicine component powder;

[0061] In the second step, the powder of the traditional Chinese medicine is sterilized at 115°C to 118°C and 1.6 to 1.8 atmospheric pressure for 30 to 40 minutes, then the sterilized medicinal materials are crushed, passed through a 100 to 140 mesh sieve, and the bacteria are kept at 1000 / Below g, if the bacteria exceed the standard, the powder can be mixed with ethanol with an alcohol concentration of 70-75%, baked at 80°C for 2 hours, left at room temperature overnight, and repeated more than two times to obtain sterilized powder of traditional Chinese medicine ingredients;

[0062] The third step is to mix the sterilized Chinese medicine component powder, the moisturizing agent and the preservative according to the ratio and put them into the deio...

Embodiment 1

[0065] Embodiment 1 The toxicity test of Chinese medicine composition of the present invention

[0066] experimental drug

[0067]25g Nansha ginseng, 16g Evodia rutaecarpa, 10g dried ginger, 15g notopterygium, 35g rhubarb, 40g Qingdai, 15g gallnut, 23g dogwood, 18g Cistanche, 25g diffusa, 25g flavescens, 12g polygala, 22g black plum, 70g coptis, 20g Mix plantain seed, 17g senna leaf, 15g kudzu root, 25g medlar, 30g licorice and 25g Atractylodes macrocephala, put them into an ultrasonic extraction tank, add 2400g of ethanol with an alcohol concentration of 85%, and extract by ultrasonic vibration for 3 times for 50 minutes. The frequency is 60kHz, and the temperature is controlled at room temperature; the extracts are combined, filtered, and the filtrate is concentrated under reduced pressure below 50°C to obtain a concentrate, dried at 80°C, pulverized into powder, and dissolved in 190ml of deionized water to obtain a solution.

[0068] experimental method

[0069] Get 40 mi...

Embodiment 2

[0070] Example 2 Preparation of Toothpaste 1

[0071] 25g Nansha ginseng, 16g Evodia rutaecarpa, 10g dried ginger, 15g notopterygium, 35g rhubarb, 40g Qingdai, 15g gallnut, 23g dogwood, 18g Cistanche, 25g diffusa, 25g flavescens, 12g polygala, 22g black plum, 70g coptis, 20g Mix plantain seed, 17g senna leaf, 15g kudzu root, 25g medlar, 30g licorice and 25g Atractylodes macrocephala, put them into an ultrasonic extraction tank, add 2400g of ethanol with an alcohol concentration of 85%, and extract by ultrasonic vibration for 3 times for 50 minutes. The frequency is 60kHz, and the temperature is controlled at room temperature; the extracts are combined, filtered, and the filtrate is concentrated under reduced pressure below 50°C to obtain a concentrated solution, which is dried at 80°C and pulverized into powder, and the powder of the traditional Chinese medicine is sterilized at 118°C and 1.7 atmospheric pressure After 40 minutes, crush the sterilized medicinal materials, pass...

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Abstract

The invention provides toothpaste for preventing and treating recurrent aphtha. The toothpaste comprises a toothpaste base material, a Chinese medicinal component additive and deionized water, wherein based on 100 weight parts of toothpaste base material, the toothpaste contains 1 to 8 weight parts of Chinese medicinal component additive and 30 to 40 weight parts of deionized water; and the Chinese medicinal component additive comprises the following components: adenophora tetraphylla, evodia rutaecarpa, dried ginger, notopterygium root, rhubarb, natural indigo, gallnut, dogwood, cistanche deserticola, oldenlandia diffusa, sophora flavescens, thin-leaf milkwort root-bark, dark plum, coptis, plantain seed, senna leaf, kudzuvine root, medlar, liquorice and large-head atractylodes rhizome. The toothpaste containing Chinese medicinal components and used for preventing and treating the recurrent aphtha has the advantages of high efficiency, small toxic or side effects, elimination of residue, elimination of medicament resistance, elimination of environmental pollution, quick response, low price, popularization, application and the like.

Description

technical field [0001] The invention belongs to the technical field of daily necessities, in particular to a toothpaste for preventing and treating recurrent aphthous ulcers. Background technique [0002] Recurrent aphthous ulcer is the recurrent oral ulcer (recurrent ulcer ROU) in Western medicine, also known as recurrent aphthous ulcer (RAU), which is isolated or multiple oral mucosal ulcers in any part of the oral mucosa irregularly or periodically. It is the most common oral mucosal disease in clinical practice. It is characterized by scattered superficial ulcers in the oral mucosa and local burning pain. It has the characteristics of localization, recurrence and self-healing. [0003] Although recurrent aphthous ulcers are not a serious or serious illness, and have no obvious systemic symptoms, they still affect daily life and work, especially when speaking or eating is very inconvenient, leading to eating disorders. Ambiguous, difficult to speak, embarrassing not to s...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/98A61K8/97A61K36/9068A61P1/02A61Q11/00A61K35/64
Inventor 戴忠明
Owner CHANGSHU HUAGANG PHARMA
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