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Chinese medicine for treating esophagus cancer and preparation method and administration way thereof

A technology of traditional Chinese medicine and turmeric, which is applied in the field of traditional Chinese medicine for treating esophageal cancer, can solve the problems of suppressed immune function, shortened survival period, decreased peripheral blood leukocytes, etc., and achieves the effects of improving clinical efficacy, small side effects and high cure rate.

Inactive Publication Date: 2012-07-04
王子熹
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

After radiotherapy, it is easy to cause side effects such as bone marrow suppression, peripheral blood leukopenia, and immune function suppression, which greatly affects the smooth completion of the treatment plan, reduces the quality of life of patients, and shortens the survival period.

Method used

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  • Chinese medicine for treating esophagus cancer and preparation method and administration way thereof
  • Chinese medicine for treating esophagus cancer and preparation method and administration way thereof

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0066] When the dosage form of Chinese medicine of the present invention is tablet, its preparation method comprises the following steps:

[0067] The first step is to fry the three ribs with vinegar;

[0068] In the first step, mix madder, white root, turmeric, salvia miltiorrhiza, and sumac according to the stated ratio, add ethanol with an alcohol concentration of 70% to 80% that is 2 to 4 times that of the mixture, and heat and reflux to extract 2 to 4 times. Reflux extraction for 1 hour to 2 hours each time, combine the extracts, remove impurities by centrifugation with a tube centrifuge, and concentrate the removed extracts under reduced pressure at 60°C to 70°C until the relative density of the drug solution is 1.05 to 1.10 (60°C), dry the concentrated solution into powder with a spray drier, and mix it with the three ribs fried in vinegar in proportion;

[0069] In the third step, mixing the proportion of astragalus, atractylodes, and thorns, and the alcohol concentra...

Embodiment 1

[0085] Embodiment 1 toxicity test

[0086] Test drug:

[0087]Stir-fry 480g Sanleng with vinegar; mix 270g madder, 300g white root, 280g turmeric, 260g salvia miltiorrhiza, and 320g sumac, add 4300g ethanol with an alcohol concentration of 80%, heat and reflux extraction twice, each time reflux extraction for 2 hours, Combine the extracts, remove impurities by centrifugation with a tube centrifuge, concentrate the extracted extracts under reduced pressure at 60°C to a relative density of the drug solution of 1.10 (60°C), and use a spray dryer to spray the concentrated solution Dry it into powder and mix it with the three ribs fried with vinegar; mix 700g Astragalus membranaceus, 450g Atractylodes macrocephala and 230g Acanthopanax acanthopanax, add 4200g ethanol with 90% alcohol concentration, heat and reflux to extract 4 times, filter, combine the filtrates, and depressurize Concentrate to a paste with a relative density of 1.20 (60°C), then extract twice with 2000g n-butano...

Embodiment 2

[0090] Embodiment 2 Chinese medicine tablet of the present invention

[0091] Stir-fry 480g Sanleng with vinegar; mix 270g madder, 300g white root, 280g turmeric, 260g salvia miltiorrhiza, and 320g sumac, add 4300g ethanol with an alcohol concentration of 80%, heat and reflux extraction twice, each time reflux extraction for 2 hours, Combine the extracts, remove impurities by centrifugation with a tube centrifuge, concentrate the extracted extracts under reduced pressure at 60°C to a relative density of the drug solution of 1.10 (60°C), and use a spray dryer to spray the concentrated solution Dry it into powder and mix it with the three ribs fried with vinegar; mix 700g Astragalus membranaceus, 450g Atractylodes macrocephala and 230g Acanthopanax acanthopanax, add 4200g ethanol with 90% alcohol concentration, heat and reflux to extract 4 times, filter, combine the filtrates, and depressurize Concentrate to a paste with a relative density of 1.20 (60°C), then extract twice with...

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Abstract

The invention provides a Chinese medicine for treating an esophagus cancer. The Chinese medicine comprises clematis root, hive, Chinese pyrola herb, inula flower, honey locust fruit, kelp, snakegourd fruit, grassleaf sweelflag rhizome, dendrobium, small centipeda herb, fineleaf schizonepeta herb, immature bitter orange, combined spicebush root, Chinese atractylodes, common bletilla pseudobulb, turmeric, red-rooted salvia root, sappan wood, common burreed rhizome, oyster, ocher, astragalus, large-head atractylodes rhizome, acanthopanax root, white paeony root and suberect spatholobus stem. TheChinese medicine provided by the invention can be used for overcoming the defects of the conventional single western medicine surgery, radiation treatment or chemotherapy for treating the esophagus cancer, and has the characteristics of small side effect, good curative effect, low cost, high curative rate, no medicament resistance and the like. When the Chinese medicine having great advantages onthe aspect of improvement on the symptom, physical sign, clinical curative effect, living quality and survival rate of a patient suffering from the esophagus cancer is used together with surgery, radiation treatment or chemotherapy treatment, the clinical curative effect is enhanced, the living quality is improved, and the curative rate is increased.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine for treating esophageal cancer. Background technique [0002] Esophageal cancer, also known as esophageal cancer, is one of the common malignant tumors of the digestive tract in humans. About 300,000 people die from esophageal cancer every year in the world, accounting for a quarter of all malignant tumor deaths. Different countries and regions, different There are marked differences in morbidity and mortality by race and sex. my country is a country with a high incidence of esophageal cancer. The incidence is generally more in the north than in the south, and more men than women. The highest age of onset is 60-64 years old, and the highest death rate is 50-65 years old, accounting for 60% of esophageal cancer deaths. above. [0003] At present, the main methods of Western medicine treatment of esophageal cancer are surgery, r...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61K9/20A61P35/00A61K33/26A61K35/56A61K35/64A61K35/618
Inventor 王子熹姜永华刘娟
Owner 王子熹
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