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Chinese medicine for treating ankylosing apondylitis and preparation method thereof

Ankylosing spondylitis and traditional Chinese medicine technology, applied in the field of medicine, can solve the problems of restricting the promotion and application of drugs, high risk of surgical treatment, high cost of medication, etc., and achieve the effect of promoting blood circulation and removing blood stasis, highlighting substantive characteristics, and low cost of medication

Active Publication Date: 2012-07-18
黄荣 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0025] In the prior art, although the emergence of biological agents has greatly improved the prognosis of this disease, there are still many, many adverse reactions to the drug, and the cost of the drug is very high, which limits the popularization and application of the drug; the risk of surgical treatment is very high. High, can damage the spinal cord and cause paraplegia of the lower limbs

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0051] Saffron 100g Sappanwood 100g Rock Coptis 100g

[0052] Take the medicinal materials of saffron, sumac and rock berberine, grind them into coarse powder, add 900g of 40% by weight ethanol to extract by percolation, filter, recover the ethanol from the filtrate, and concentrate the liquid to 180g, let the concentrated solution stand for 3 days, filter After filtration, the filtrate was first added with hydrochloric acid to adjust the pH to 3.5-4.0, left to stand for 1 day, filtered, and the filtrate was adjusted to PH to 8.0 with sodium hydroxide solution to obtain the active ingredient of the present invention.

Embodiment 2

[0054] Saffron 300g Sappanwood 300g Rock Coptis 200g

[0055] Take saffron, sumac, and rock berberine medicinal materials, grind them into coarse powder, add 4800g of ethanol with a weight percentage of 90% to extract by percolation, filter, recover ethanol from the filtrate, and concentrate the liquid to 1200g, leave the concentrated solution for 10 days, filter After filtering, the filtrate was heated at 70°C for 1 hour, then left at room temperature for 1 day, and then heated at 70°C for 1 hour. Repeat this three times, filter, add purified water to a total amount of 1800g, and then add 16.2g of sodium chloride to adjust the osmotic pressure , so that the osmotic pressure of the solution is consistent with that of blood plasma, and the solution with adjusted osmotic pressure is allowed to stand at 1° C. for 6 days, filtered, filled, and sterilized to obtain the injection solution of the present invention.

Embodiment 3

[0057] Saffron 100g Sappanwood 400g Rock Coptis 200g

[0058] Take the medicinal materials of saffron, sumac and rock berberine, crush them into coarse powder, add 5600g of ethanol with a weight percentage of 60% to extract by percolation, filter, recover ethanol from the filtrate, and concentrate the liquid to 560g, leave the concentrated solution for 6 days, filter After filtering, add hydrochloric acid to the filtrate to adjust the pH to 3.5~4.0, let it stand for 1 day, filter, adjust the pH to 8.0 with sodium hydroxide solution, add purified water, appropriate amount of sucrose, and preservatives to a total amount of 1000g, and obtain this product Oral solution was invented.

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Abstract

The invention discloses a Chinese medicine for treating ankylosing apondylitis and a preparation method thereof. The Chinese medicine adopts crocus sativus, sappanwood and corydalis thalictrifolia as the main components, is prepared through Chinese medicine traditional process, is reasonable and scientific in process and simple to operate, and has the functions of anti-inflammatory analgesia, dregging meridians and collaterals, activating blood, removing stasis, dispeling wind, removing dampness and adjusting endocrine and hematopoietic function. The Chinese medicine for treating ankylosing apondylitis and the preparation method of the Chinese medicine overcome the defects that an existing technology is not accurate in curative effect and large in side effect, and the ankylosing apondylitis is difficult to cure once and for all. The Chinese medicine has the advantages of being accurate in curative effect, low medicine use cost, small in side effect and the like, and makes great progress in the field of treating the ankylosing apondylitis.

Description

technical field [0001] The invention relates to the field of medicine, in particular to a traditional Chinese medicine for treating ankylosing spondylitis and a preparation method thereof. [0002] Background technique [0003] Ankylosing spondylitis is an ancient disease, which was described as early as in ancient Egypt. There was a formal medical record of ankylosing spondylitis in 1691, but it has always been considered a variant of rheumatoid arthritis and was called "rheumatoid arthritis, central type" or "rheumatoid spondylitis". It was not until 1973 that people discovered that ankylosing spondylitis was related to HLA-B27. Later, as the understanding of ankylosing spondylitis continued to deepen, ankylosing spondylitis was separated from rheumatoid arthritis, called the category of spondyloarthritis . At present, it is generally believed that the incidence of ankylosing spondylitis in women is lower than that in men. The ratio of men to women is (2~3): 1. Peripher...

Claims

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Application Information

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IPC IPC(8): A61K36/88A61P19/02A61P29/00
Inventor 黄荣
Owner 黄荣
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