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Method for preparing atomized liquid for treating infantile asthmatic suffocating pneumonia

A technology for nebulized liquid and pneumonia, which is applied in the field of the preparation of nebulized liquid for treating asthmatic pneumonia in children, and can solve problems such as affecting development, decreasing drug sensitivity, and negative protein balance.

Active Publication Date: 2013-08-21
南通东湖国际商务服务有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there are actually the following problems: ① Insufficient treatment, because the basic pathogen of airway inflammation is syncytial virus, and there is no specific drug for this virus in Western medicine at present; ② The use of hormones, in infant patients The use of hormones has a clear limit on the amount. In addition to the common side effects of hormones, children who use hormones for a long time, because hormones have the effect of antagonizing growth hormone, can also cause protein negative balance and affect development; ③ long-term use of bronchodilators is likely to cause Decreased β2 receptor sensitivity, resulting in decreased drug sensitivity
Therefore, there is still a lack of clinically effective and less side effect drugs for the treatment of children with asthmatic pneumonia.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] Example 1, raw material drug weight ratio: 3 parts of saponins, 9 parts of loquat leaves, 15 parts of hops, 15 parts of winter melon seeds, 9 parts of orchid vanilla, 9 parts of bellflower, 10 parts of red clover, 6 parts of peucedanum, 1 part of borneol share.

Embodiment 2

[0023] Example 2, raw material drug weight ratio: 1 part of saponins, 6 parts of loquat leaves, 10 parts of hops, 10 parts of winter melon seeds, 6 parts of orchid vanilla, 6 parts of bellflower, 15 parts of red clover, 9 parts of peucedanum, 3 parts of borneol share.

Embodiment 3

[0024] Example 3, raw material drug weight ratio: 2 parts of saponins, 8 parts of loquat leaves, 12 parts of hops, 12 parts of winter melon seeds, 8 parts of orchid vanilla, 8 parts of bellflower, 12 parts of red clover, 8 parts of peucedanum, 2 parts of borneol share.

[0025] The preparation steps of embodiment 1~3 are as follows:

[0026] (1) Take loquat leaves, hops, orchid vanilla, grind them, and extract them by supercritical fluid extraction to obtain volatile oil;

[0027] (2) Take acacia and borneol, crush them, and pass through a 200-mesh sieve to obtain superfine powder;

[0028] (3) Take red clover, peucedanum, wax gourd seeds, platycodon grandiflorum and decoct twice, filter, combine the filtrate, concentrate at 80°C to a relative density of 1.1, and obtain a water extract;

[0029] (4) Add the volatile oil obtained in step 1 and the superfine powder obtained in step 2 to the water extract obtained in step 3, stir evenly, let stand at room temperature for 12 hou...

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PUM

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Abstract

The invention discloses a method for preparing atomized liquid for treating infantile asthmatic suffocating pneumonia. The atomized liquid comprises gleditsia fruit, loquat leaf, European hop flower, Chinese waxgourd semen, common bluebeard herb, platycodon root, red clover, whiteflower hogfennel root and borneol which serve as raw materials. The method is characterized by comprising the following steps of: (1) extracting the loquat leaf, the European hop flower and the common bluebeard herb by a supercritical fluid extraction method to obtain volatile oil; (2) crushing the gleditsia fruit and the borneol into superfine powder; (3) decocting the red clover, the whiteflower hogfennel root, the Chinese waxgourd semen and the platycodon root in water twice, filtering, mixing filtrates, and concentrating at the temperature of 80 DEG C until the relative density is 1.1 to obtain a water extracting solution; and (4) stirring the volatile oil obtained in the step (1), the superfine powder obtained in the step (2) and the water extracting solution obtained in the step (3) uniformly, standing at normal temperature for 12 hours, and filtering to obtain liquid medicine. Clinical experiments prove that the atomized liquid prepared by the method has an obvious treatment effect, and the hospital stays can be shortened.

Description

technical field [0001] The invention relates to the field of hospital nursing, in particular to a preparation method of an atomized liquid for treating children with asthmatic pneumonia. Background technique [0002] Asthmatic pneumonia, also known as bronchiolitis, is more common in children under 2 years old, and occurs frequently in winter and spring. It is a common lower respiratory tract infectious disease in infants and young children. The main pathogens of asthmatic pneumonia are viruses, the most common being respiratory syncytial virus RSV. After the onset, it manifests as cough, wheezing, dyspnea, and extensive wheezing in the lungs. In severe cases, cardiac insufficiency and respiratory failure occur. The basis and pathological features of its asthma attack are airway inflammation and hyperresponsiveness, mainly manifested by inflammatory cell infiltration and epithelial cell damage mainly composed of eosinophils. Eosinophils are powerful pro-inflammatory cells....

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/85A61K9/12A61P11/00A61K31/045
Inventor 陈祥胜
Owner 南通东湖国际商务服务有限公司
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