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Method for extracting pummelo peel

An extraction method, the technology of tangerine red, which is applied in the field of tangerine red extraction, can solve the problems of underutilization of active ingredients, waste of resources, lack of comprehensive utilization, etc.

Inactive Publication Date: 2012-10-10
SUN YAT SEN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although the research on tangerine red has achieved remarkable results, the research on tangerine red is now limited to a certain component or a certain type of composition, so that its active ingredients have not been fully utilized, resulting in a waste of resources. Comprehensive use of research reports

Method used

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  • Method for extracting pummelo peel

Examples

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Effect test

Embodiment 1

[0009] The comprehensive extraction of embodiment 1 orange red

[0010] Take 5000 grams of Huajuhong medicinal material, add water to decoct three times, add 10 bits of water each time, filter, decoction is concentrated to a relative density of 1.20 (measured at 70°C), add ethanol until the alcohol concentration is 50%, and stand for 12 hours. Filtrate to get the filtrate and precipitate; the above precipitate is dried to obtain the citrus red extract (citrus tangerine extract I), which can be used as dietary fiber, directly applied or added to other foods, and made into a weight-loss or liver-protecting anti-alcohol Functional health food; the above-mentioned filtrate recovers ethanol to an alcohol-free extract, adds water to adjust the relative density to 1.10 (measured at 60°C-80°C), places it for 5 days, filters, and dries the solid to obtain the citrus flavonoid extract (citrus red extract Substance II), the extract contains more than 50% naringin, which can be used to ...

Embodiment 2

[0011] Example 2 The protective effect of citrus red extract I on acute alcoholic liver injury

[0012] SPF grade Kunming mice, male, 18g-20g, provided by Guangdong Medical Animal Experiment Center, certificate number: SCXK (Guangdong) 2008-0002. Mice were randomly divided into 6 groups, 12 in each group. The blank was divided into blank control group, model control group, Huajuhong extract I low, medium and high dose groups, Dangfei Liganning group (positive control group).

[0013] Each group was intragastrically administered according to body weight, and the model group and blank group were intragastrically administered equal volumes of distilled water. Continuous administration for 10 days, 30 minutes after the last administration, each group was intragastrically administered 50% ethanol at a dose of 14 mL / kg, and the blank group was intragastrically administered an equal volume of distilled water.

[0014] After 16 hours of drinking, the mice were weighed, the eyeball...

Embodiment 3

[0026] Example 3 The effect of citrus red extract I on the drunkenness of mice

[0027] Determination of the optimal amount of alcohol given to mice: Take SPF-grade Kunming mice, male, 18g-20g, provided by Guangdong Medical Animal Experiment Center, certificate number: SCXK (Guangdong) 2008-0002. Randomly divided into 3 groups, 10 in each group. Group 1, Group 2, and Group 3 were given Red Star Erguotou at 15ml / kg, 18ml / kg, and 20ml / kg, respectively. Observe the activity of the mice, record the number of mice with lost righting reflex, the number of dead mice and the time of sobering up in each group. According to the observation result, choose the most suitable amount of alcohol.

[0028] See Table 3 for the experimental results of the optimal amount of alcohol given to mice. 17ml / kg was adopted as the experimental alcohol intake.

[0029] Table 3 Determination of the optimal amount of alcohol given to mice

[0030] Give alcohol total number drunk rate ...

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Abstract

The invention relates to a method for extracting pummelo peel, which comprises the following steps: taking the pummelo peel medicinal materials, decocting with water and filtering, decocting until the relative density of the decoction is concentrated to 1.05-1.30, adding ethanol or (and) methanol for ethanol precipitation, and filtering the generated precipitate to obtain the filtrate and precipitate. The precipitate can be used as dietary fiber after being dried, and is directly applied or added into other food; the filtrate is an extract without the alcohol taste after recovering ethanol, is added with water to regulate the relative density of 1.05-1.15, and is stood for more than 3 days, the precipitate is separated out and filtered, so the precipitate and the filtrate are obtained; and the precipitate is taken out to be dried. The naringin content of the extract is higher than 50%, the naringin can be used for preparing medicaments for relieving cough and reducing sputum, and the filtrate can be produced into a pummelo peel drink after mixing.

Description

technical field [0001] The invention relates to a method for extracting tangerine red. Background technique [0002] Huajuhong comes from the Rutaceae plant Huazhou pomelo Citrus gruandis (L.) Osbeck var. tomentosa Hort. or grapefruit Citrus gruandis (L.) The immature or near-ripe dry outer pericarp of Osbeck, the former is commonly called "Maojuhong", the latter is called "Guangjuhong", or its dry young fruit. Huazhou Juhong is an authentic medicinal material in Guangdong. It is famous for its unique effect of reducing phlegm and relieving cough. The records first appeared in "Guangdong Tongzhi" in the 14th year of Kangxi (AD 1675), and "Compendium of Materia Medica Supplements" has separated its official establishment. Huajuhong mainly contains polysaccharides (with pectin as the main component), flavonoids and coumarins, and small molecular sugars. [0003] Huajuhong is a variety recorded in the Pharmacopoeia of the People's Republic of China. It is a genuine medicina...

Claims

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Application Information

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IPC IPC(8): A61K36/752A23L1/30A23L2/06A61P11/10A61P11/14A61K131/00
Inventor 苏薇薇吴忠王永刚
Owner SUN YAT SEN UNIV
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