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34results about How to "Strong industrialization" patented technology

Method for catalytic preparation of 5-hydroxymethyl furfural from carbohydrates

The invention relates to a niobium-containing compound catalyst for efficiently converting carbohydrates into 5-hydroxymethyl furfural, which has high activity and selectivity for preparing hydroxymethyl furfural (HMF) by dehydrolyzing saccharides and is an ideal catalyst for preparing HMF. When the reaction is performed under moderate conditions, the target product HMF can have a high yield. The catalyst is environment-friendly, is easy to separate and recycle, can be reused, is convenient and practical to operate, and can not corrode the equipment, thereby being an ideal solid acid catalyst for preparing HMF, and having significant industrial application meanings.
Owner:DALIAN INST OF CHEM PHYSICS CHINESE ACAD OF SCI

Compound telmisartan amlodipine besylate medicinal composition and preparation method thereof

The invention discloses a compound telmisartan amlodipine besylate medicinal composition. The composite is a tablet which is prepared by the following steps: preparing amlodipine besylate into amlodipine besylate solid dispersion by a solid-state dispersion technology; and preparing the amlodipine besylate solid dispersion and telmisartan into the composite. The tablet improves the dissolubility of primary medicine, promotes the medicament to be quickly disintegrated, prevents dissolution influence of meglumine to the amlodipine besylate, simultaneously improves the absorptivity in blood, and improves the bioavailability of the primary medicine. The tablet has excellent curative effect to hypertension symptoms.
Owner:天津汉一医药科技有限公司

Method for extracting pummelo peel

The invention relates to a method for extracting pummelo peel, which comprises the following steps: taking the pummelo peel medicinal materials, decocting with water and filtering, decocting until the relative density of the decoction is concentrated to 1.05-1.30, adding ethanol or (and) methanol for ethanol precipitation, and filtering the generated precipitate to obtain the filtrate and precipitate. The precipitate can be used as dietary fiber after being dried, and is directly applied or added into other food; the filtrate is an extract without the alcohol taste after recovering ethanol, is added with water to regulate the relative density of 1.05-1.15, and is stood for more than 3 days, the precipitate is separated out and filtered, so the precipitate and the filtrate are obtained; and the precipitate is taken out to be dried. The naringin content of the extract is higher than 50%, the naringin can be used for preparing medicaments for relieving cough and reducing sputum, and the filtrate can be produced into a pummelo peel drink after mixing.
Owner:SUN YAT SEN UNIV

Iloperidone pharmaceutical composition and preparation method thereof

The invention discloses an iloperidone pharmaceutical composition and a preparation method thereof. The invention is characterized in that 1000 iloperidone pharmaceutical composition tablets are prepared from the following components: 1-24g of iloperidone, lactose, microcrystalline cellulose, croscarmellose sodium, magnesium stearate, 5% povidone K30 and a proper amount of 70% ethanol solution. The invention also relates to the preparation method of the iloperidone pharmaceutical composition. The iloperidone tablet prepared by the prescription and preparation method provided by the invention has the advantages of good liquidity, good dissolution rate, small tablet weight variation, high bioavailability and good treatment effect.
Owner:TIANJIN HANKANG PHARMA BIOTECH

Hyperbranched polymer based on carbon nanotube and preparation method thereof

The invention provides a preparation method of a hyperbranched polymer based on a carbon nanotube, wherein the preparation method comprises the following steps: step 1, taking a hydroxylated carbon nanotube, and grafting a silane coupling agent on the surface of the hydroxylated carbon nanotube, wherein the silane coupling agent containing an amino-terminated group; step 2, carrying out at least one time of hybridization treatment on the product in the step 1, wherein the hybridization treatment process comprises the following steps of sequentially grafting methyl acrylate and organic diamine on the product in the step 1; step 3, taking the product in the step 2, and carrying out end capping on the product by adopting maleic anhydride; and step 4, taking 0.1 part by weight of the product obtained in the step 3, and carrying out water-phase free radical copolymerization on the product and 20-40 parts by weight of acrylamide. According to the hyperbranched polymer disclosed by the invention, a polymerization main body is a one-dimensional carbon nanotube, and compared with a traditional hyperbranched polymer, the hyperbranched polymer can pass through a pore throat with a smaller size; and meanwhile, the synthesis method is simple, high in repeatability, energy-saving and environment-friendly in process and high in industrialization.
Owner:SOUTHWEST PETROLEUM UNIV

Compound telmisartan hydrochlorothiazide pharmaceutical composition and preparation method thereof

The invention discloses a compound telmisartan hydrochlorothiazide pharmaceutical composition, which is a tablet. For the tablet, hydrochlorothiazide and telmisartan are prepared into a coated tablet so as to make the telmisartan and the hydrochlorothiazide in the telmisartan hydrochlorothiazide pharmaceutical composition respectively released. The composition has a controlled release effect and improves the bioavailability. The employment of a coated tablet preparation process can make the two medicines effectively released successively. The pharmaceutical composition has a controlled release effect, maintains a long-term blood concentration, has a more stable blood pressure reduction effect, and reduces adverse reactions.
Owner:庞晓斌

Gas guide type anaerobic reactor

The invention relates to a gas guide type anaerobic reactor. The gas guide type anaerobic reactor comprises one or a plurality of anaerobic reaction tanks connected in series; a water inlet, a water outlet, an exhaust port and a slag outlet are formed in the outer part of each of the anaerobic reaction tanks; a feed plate, a guide plate and a sludge plate are arranged at the inner part of each of the anaerobic reaction tanks, wherein the feed plate is arranged at one side close to the water inlet; the sludge plate is arranged at one side close to the water outlet; the guide plate is arranged between the feed plate and the sludge plate; the guide plate and the sludge plate are movably connected to the inner part of each of the anaerobic reaction tanks; the feed plate and the guide plate define a sludge suspension area; the guide plate and the sludge plate define a precipitating area; a reaction area is formed in the bottom part of each of the reaction tanks. Compared with the prior art, the gas guide type anaerobic reactor has the advantages that the muddy water reaction time and the sludge precipitation time can be adjusted by controlling the volumes of the sludge suspension area and the sludge precipitating area; in addition, the gas guide type anaerobic reactor has good load to impact, and is high in fermenting efficiency, wide in applicable range, high in sludge utilization rate, low in energy consumption, simple in design, and convenient in equalization.
Owner:SHANGHAI JIAO TONG UNIV

High-strength and high-corrosion-resistance ternary magnesium alloy and preparation method thereof

The invention relates to a high-strength and high-corrosion-resistance ternary magnesium alloy and a preparation method thereof. The magnesium alloy comprises, by mass, 8-12 wt% of Y, 0.6-3 wt% of Aland the balance Mg. The method comprises the following steps that (1) under a protective atmosphere, a Mg-Y intermediate alloy, an aluminum ingot and a magnesium ingot are prepared to prepare a magnesium alloy melt; (2) under the protective atmosphere, the magnesium alloy melt stands after being stirred, refining and degassing, and slag removal are carried out, and the magnesium alloy melt standsagain and preserves heat to obtain magnesium alloy liquid; (3) the magnesium alloy liquid is cast into a mold under the protective atmosphere to form a cast ingot; and finally, the high-strength and high-corrosion-resistance ternary magnesium alloy is obtained through the above three steps. Compared with the prior art, the method has the advantages of being good in corrosion resistance, high in mechanical property, low in sensitivity to impurity iron elements and simple in preparation process.
Owner:SHANGHAI JIAO TONG UNIV

Guacetisal dry-mixing suspending agents and method of preparing the same

The invention relates to a guacetisal dry suspension, the formula of which for preparing 1,000 bags comprises the following raw materials (by weight parts) guacetisal 160-170, hydroxypropyl methyl cellulose 5-10, sodium lauryl sulfate 5-10, sucrose 815-820, and a proper amount of fresh milk essence, wherein the sodium lauryl sulfate is used as a wetting agent for facilitating suspension. The guacetisal dry suspension has the advantages of good settling volume ratio, long suspension state keeping time, good stability, and good mouthfeel; and is more suitable for administration by children and patients suffering from dysphagia.
Owner:SHANDONG LUOXIN PARMACEUTICAL GROUP STOCK CO LTD +1

Concrete vibrating compaction device for municipal engineering construction

The invention discloses a concrete vibrating compaction device for municipal engineering construction. A vehicle bottom plate is provided with a vertical cut-through conical hole, the hole diameter ofthe conical hole is in a big-end-down manner, a vibrating bar is inserted into the conical hole from top to bottom in a penetrating manner, and a hole opening formed in the upper end of the conical hole is attached to the outer wall of the vibrating bar. The angle that the vibrating bar is inserted into concrete and the inclination angle of the vibrating bar are mainly adjusted in a manual mannerbefore construction; and after the inserting depth and the inclination angle of the vibrating bar are adjusted in place, the front-back positions of a first clamping block and a second clamping blockare adjusted, and the vibrating bar is positioned through the first clamping block and the second clamping block. The vibrating bar can be conveniently moved through an operation guiding vehicle, andthe surface of the concrete can be automatically leveled and pressed through the vehicle bottom plate. When the concrete vibrating compaction device for municipal engineering construction is used, not only is the effect good, but also operation is easy and convenient, the concrete vibrating effect is basically same after operation even though the device is operated by different construction personnel, and industrialization is high.
Owner:逯龙

Medicine composition of dronedarone hydrochloride solid dispersion and preparation method thereof

The invention discloses a medicine composition of dronedarone hydrochloride, which is a dispersible tablet. The medicine composition is a tablet which is prepared from dronedarone hydrochloride micronized by a solid dispersion technology and an auxiliary material. According to the medicine composition, the dissolubility of the primary medicine is improved, rapid disintegration of the medicine is facilitated, the absorbability of the medicine in the blood is increased, and the bioavailability of the primary medicine is improved. Moreover, the medicine composition has a favorable treatment effect on symptoms such as arrhythmia, atrial fibrillation and the like.
Owner:开封大宋制药有限公司

Fabricated steel-wood combined arch bridge structure and construction method thereof

The invention discloses a fabricated steel-wood combined arch bridge structure and a construction method thereof, and relates to the technical field of bridge construction, the fabricated steel-wood combined arch bridge structure is formed by sequentially connecting a plurality of spatial dodecahedrons; the spatial dodecahedron comprises a plurality of corner connecting pieces and structural rod piece units; the corner connecting piece comprises a three-way connecting piece and a four-way connecting piece; each structural rod piece unit comprises a single structural rod and a split structural rod; the split structure rod is formed by two symmetrical semi-cylinder structures which are movably connected in an inserted mode through a tenon-and-mortise structure. The three adjacent single structural rods in the same space dodecahedron are connected through three-way connecting pieces; the five four-way connecting pieces located at the connecting face positions of every two adjacent space dodecahedrons are connected with two single structure rods and two split structure rods respectively. The bridge structure is diversified, good in stress condition and excellent in structural stability, and by combining light high-strength materials, the bridge structure is light in self weight, has the space utilization rate and attractive shape, and breaks through a traditional bridge structure form at the same time.
Owner:JINLING INST OF TECH

Preparation method of all-solid-state battery, and all-solid-state battery

The invention provides a preparation method of an all-solid-state battery, and the all-solid-state battery. The preparation method comprises the following steps: assembling an all-solid-state battery assembly, injecting a solid electrolyte solution, and conducting drying to obtain the all-solid-state battery. According to the invention, the all-solid-state battery assembly is filled into the solid electrolyte solution, so an ion path is formed, an interface between electrodes and the electrolyte is improved, the need of adding the solid electrolyte and an additive in the preparation process of the electrode of the all-solid-state battery is avoided, the use of highly toxic solvents such as ethylbenzene is avoided, and limitation on the environmental dew point in the electrode preparation process is effectively avoided; and the preparation method provided by the invention can be compatible with existing liquid lithium ion battery production equipment, and has the characteristics of being simple in preparation process, easy to industrialize, high in applicability and the like.
Owner:CHINA FIRST AUTOMOBILE

Nanometer titanium dioxide solid particle emulsifier and preparation method thereof

The invention provides a nano titanium dioxide solid particle emulsifier and a preparation method thereof. The nano titanium dioxide solid particle emulsifier is prepared by the method comprising the following steps: dissolving titanium dioxide in absolute ethyl alcohol, and performing ultrasonic treatment to obtain dispersion liquid; adding a phthalic ester coupling agent into the dispersion liquid for chemical grafting; adding a certain amount of brominated alkane after heating and stirring for a period of time, and heating and stirring for a period of time; and after heating and stirring, carrying out suction filtration and drying to obtain the nano oleophylic titanium dioxide solid particle emulsifier. The nano emulsifier can form a stable water-in-oil emulsion under the condition that the water saturation of an oil reservoir is 10-80% through the shearing action of a stratum, the viscosity of the emulsion is 1.5-22 times that of crude oil, and the viscosity of the emulsion is in direct proportion to the water saturation of the oil reservoir within the range of the water saturation of the oil reservoir; the high-viscosity emulsion formed under the condition of high water content can block a dominant channel so as to achieve the purposes of controlling the fluidity and stabilizing the displacement front edge, and the crude oil recovery rate is improved.
Owner:SOUTHWEST PETROLEUM UNIV

Compound valsartan amlodipine besylate pharmaceutical composition and preparation method thereof

The invention relates to a compound valsartan benzenesulfonic acid amlodipine medicament composition and a new preparation method thereof. The compound valsartan benzenesulfonic acid amlodipine medicament composition is in a capsule type and is prepared by adopting the preparation method of a solid dispersion technique so that the dissolution of a medicament and the adsorption of the medicament in gastrointestinal tracts can be obviously promoted. The preparation method overcomes the defects of poor dissolution outside benzenesulfonic acid amlodipine and low bioavailability, greatly improve the quality of a preparation product and can realize industrial production.
Owner:天津汉嘉医药科技有限公司

Naphthyl ammonium salt compound as well as preparation method and application thereof

The invention discloses a naphthyl ammonium salt compound as well as a preparation method and application thereof. According to the preparation method disclosed by the invention, the characteristic that organic ammonium salt with a special structure is soluble in water while is insoluble or slightly soluble in an organic solvent is utilized; meanwhile, the organic ammonium salt is combined with inorganic acid or inorganic alkali to carry out acid-base exchange reaction; a compound shown as a structural formula I is purified at high yield and a time and is added with a reaction product so as toprovide powerful guarantee for industrially producing 6-nitro-1,2-diazoxy-4-naphthalene sulfonic acid with excellent quality. The preparation method of the naphthyl ammonium salt disclosed by the invention has the advantages of simple operation, no need of special production equipment, no special reaction process of potential safety hazards and extremely-high industrialization; meanwhile, all organic alkali can be recycled effectively so as to reduce the process cost and improve environmental compatibility of the method.
Owner:JIUJIANG SHANSHUI TECH

Guacetisal dry-mixing suspending agents and method of preparing the same

The invention relates to a guacetisal dry suspension, the formula of which for preparing 1,000 bags comprises the following raw materials (by weight parts) guacetisal 160-170, hydroxypropyl methyl cellulose 5-10, sodium lauryl sulfate 5-10, sucrose 815-820, and a proper amount of fresh milk essence, wherein the sodium lauryl sulfate is used as a wetting agent for facilitating suspension. The guacetisal dry suspension has the advantages of good settling volume ratio, long suspension state keeping time, good stability, and good mouthfeel; and is more suitable for administration by children and patients suffering from dysphagia.
Owner:SHANDONG LUOXIN PHARMA GRP CO LTD +1

Disc type node scaffolding

The invention relates to a disc-shaped node-type scaffold for building construction, which includes a multi-layer construction operation surface, and each layer of the construction operation surface includes a plurality of disc-shaped fixing devices installed on both ends of the small cross bar by small cross bars. Among them: the disc-shaped fixing device (5) is a disc-shaped object, and the six faces of the disc-shaped object are provided with threaded holes (11) for the disc-shaped fixing device, and the two ends of the disc-shaped object are provided with disc-shaped The fixing device matches the through hole (21); each vertical column (1) inside the disc-shaped node scaffold is installed with guide rails (8) and triangular pieces (9) connected with the inner and outer columns at intervals, and the guide rails (8) The upper part is equipped with an attached support. The disc-shaped node-type scaffold has simple structure, reliable load bearing, no eccentric column load bearing, high overall rigidity, easy installation, convenient material acquisition and processing, and can be prefabricated in factories, with strong industrialization.
Owner:北京韬盛科技发展有限公司

A kind of preparation method and application of carbon-based solid acid

The invention belongs to the technical field of biomass catalysis, and specifically relates to a preparation method and application of a carbon-based solid acid. The invention uses one or more of glucose, fructose, starch, and sucrose as a carbon source, and adds an appropriate amount of liquid acid to the catalyst Carry out modification to prepare carbon-based solid acid; use the prepared carbon-based solid acid to catalyze the reaction of carbohydrates to prepare 5-hydroxymethylfurfural, which has a mild reaction process, the catalyst used is environmentally friendly, and the process is simple and economical. The industrialized preparation of the platform compound 5-hydroxymethylfurfural provides a new way to promote the preparation of petroleum-based chemicals and alternative fuels from biomass, which has strong industrial significance.
Owner:JIANGSU UNIV OF TECH

A self-calibration method of laser displacement sensor

The invention discloses a laser displacement sensor self-calibration method, which overcomes the problem of low laser calibration accuracy and low efficiency in the prior art. By defining theoretical tool coordinates for the laser sensor, the robot holds the laser displacement sensor to move and record data. According to the The data call algorithm calculates the direction relationship and size relationship between the sensor and the robot base coordinates; moves the robot so that the laser reading is 0 and records the sensor coordinates, and rotates and transforms the posture to record the readings; calculates the deviation between the theoretical coordinates and the actual coordinates, and calculates the actual coordinates according to the deviation; Transform poses repeatedly until the error value reaches precision. The present invention is based on the laser tool self-calibration technology of the industrial six-axis robot. Through the irradiation and movement of the sensor by the laser displacement sensor installed on the robot, the precise coordinates of the laser tool are calculated to achieve high precision, high efficiency, and automatic calibration. Effect.
Owner:NINGBO DAZHENG IND ROBOT TECH CORP

Gas guide type anaerobic reactor

The invention relates to a gas guide type anaerobic reactor. The gas guide type anaerobic reactor comprises one or a plurality of anaerobic reaction tanks connected in series; a water inlet, a water outlet, an exhaust port and a slag outlet are formed in the outer part of each of the anaerobic reaction tanks; a feed plate, a guide plate and a sludge plate are arranged at the inner part of each of the anaerobic reaction tanks, wherein the feed plate is arranged at one side close to the water inlet; the sludge plate is arranged at one side close to the water outlet; the guide plate is arranged between the feed plate and the sludge plate; the guide plate and the sludge plate are movably connected to the inner part of each of the anaerobic reaction tanks; the feed plate and the guide plate define a sludge suspension area; the guide plate and the sludge plate define a precipitating area; a reaction area is formed in the bottom part of each of the reaction tanks. Compared with the prior art, the gas guide type anaerobic reactor has the advantages that the muddy water reaction time and the sludge precipitation time can be adjusted by controlling the volumes of the sludge suspension area and the sludge precipitating area; in addition, the gas guide type anaerobic reactor has good load to impact, and is high in fermenting efficiency, wide in applicable range, high in sludge utilization rate, low in energy consumption, simple in design, and convenient in equalization.
Owner:SHANGHAI JIAOTONG UNIV

P type layer open pipe Al diffusion silicon element and preparation method thereof

The invention relates to the field of thyristors, in particular to a preparation method of a P type layer open pipe Al diffusion silicon element. The preparation method comprises the following steps: firstly, plating an Al film layer on a Si surface; secondly, forming an Al-Si alloy layer in an alloying way, namely the Si surface comprises an Al-Si alloy layer and the Al film layer; thirdly, removing the Al film layer, thus obtaining the Al-Si alloy layer as an Al impurity source; fourthly, advancing junction depth of the Al-Si alloy layer and the Si layer for a certain time at a certain temperature and under certain atmosphere, so that Al diffuses toward Si; and fifthly, carrying out aftertreatment, so that the product is obtained. The preparation method provided by the invention is simple in technology, strong in industrialization capability, low in requirement on equipment, good in product uniformity and good in diffusion consistency.
Owner:富芯微电子有限公司

Preparation method of graft modified fish protein-sugar coupled compound

PendingCN113651972AImprove the degree of graftingImprove solubilityProtein proteinFish Proteins
The invention discloses a preparation method of a graft modified fish protein-sugar coupled compound, which comprises the following steps: dissolving protein in a high-ionic-strength buffer solution, and performing high-speed shearing to obtain a uniform myofibrillar protein solution; subjecting the myofibrillar protein solution to high-pressure homogenization pretreatment to expand protein, so that the alpha-helix content of the myofibrillar protein solution is increased, glycosylation sites of the myofibrillar protein solution are increased, then subjecting the myofibrillar protein solution and glucosamine to a wet glycosylation reaction in a water phase, and stabilizing the natural protein structure and improving the glycosylation degree by utilizing a macromolecular crowding theory; and performing dialysis desugaring on a product obtained after the glycosylation reaction, and performing vacuum freeze drying to obtain the grafted modified protein-sugar coupled compound disclosed by the invention. Compared with a traditional glycosylation mode, the preparation method disclosed by the invention has the advantages that the grafting degree of the myofibrillar protein and the glycosyl donor and the solubility of the myofibrillar protein in a low-ion solvent can be remarkably improved, and the oxidation resistance of the myofibrillar protein is also improved.
Owner:ZHEJIANG GONGSHANG UNIVERSITY

Laser displacement sensor self-calibration method

The invention discloses a self-calibration method for a laser displacement sensor, and solves the problems of low laser calibration precision and low efficiency in the prior art. The method comprisesthe steps: defining theoretical tool coordinates for a laser sensor, enabling a robot to hold a laser displacement sensor to move and record data, and calculating a direction relation and a size relation between the sensor and a robot base coordinate according to a data calling algorithm; enabling the laser reading to be 0 through a mobile robot, recording the coordinates of the sensor, and changing the posture to record the reading; calculating a deviation between the theoretical coordinates and the actual coordinates, and calculating the actual coordinates according to the deviation; and repeatedly changing the attitude until the error value reaches the precision. According to the laser tool self-calibration technology based on the industrial six-axis robot, accurate laser tool coordinates are calculated through irradiation and movement of the laser displacement sensor installed on the robot to the inductor, and the effects of high precision, high efficiency and automatic calibrationare achieved.
Owner:NINGBO DAZHENG IND ROBOT TECH CORP
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