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Traditional Chinese medicine composition for improving postpartum hypogalactia and preparation method thereof

A technology of postpartum hypogalactia and composition, which is applied in the field of traditional Chinese medicine, can solve problems such as poor flow of qi and blood, blood stasis in the collaterals, and imbalance of qi and blood, so as to treat postpartum hypogalactia, increase lactation, and achieve quick results Effect

Inactive Publication Date: 2014-10-29
钟山县红花镇中心卫生院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Therefore, the treatment of soothing the liver, relieving stagnation and dredging collaterals is needed. Due to postpartum physical weakness, poor rest, and prolonged lying, etc., it is easy to cause stagnation of qi, poor circulation of qi and blood, blood stasis in the collaterals, poor blood flow; phlegm condenses, phlegm stasis Cause milk swelling in the breast; stagnation of Qi due to stagnation of the liver, deficiency of the kidney due to stagnation of the liver, leading to imbalance of Qi and blood, deficiency of Chong and Ren

Method used

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Effect test

preparation example Construction

[0062] The present invention also provides a preparation method of the above-mentioned Chinese medicine composition, when the dosage form of the Chinese medicine composition is an oral liquid, it includes the following steps,

[0063] In the first step, the components are mixed in proportion, placed in an ultrafine pulverizer for 20-40 minutes, and the pulverized powder is dissolved in ethanol with an alcohol concentration of 85%-95%, and soaked for 12 hours- For 18 hours, use the percolation method to slowly percolate at a rate of 1-2ml per minute, collect the percolation liquid, the quality of the added ethanol is 2-4 times the mass of the mixed powder, and concentrate under reduced pressure to 1 / 2 of the original volume. About 10, centrifuge at 15000rpm to obtain the supernatant;

[0064]In the second step, the supernatant obtained in the first step is adsorbed on a macroporous resin column, first eluted with water 2 to 4 times the mass of the mixture obtained in the first ...

Embodiment 1

[0077] The powder 1 that the present invention prepares of embodiment 1

[0078] Jiangbuliuxing 55g, Passepartout 42g, Astragalus 76g, Polygonatum 27g, Atractylodes macrocephala 24g, Acacia 21g, Achyranthes bidentata 30g, Shannai 18g, Rehmannia glutinosa 22g, Shouwuteng 48g, Qumai 26g, Plantain 17g, Shiwei 20g, coix seed 25g, bellflower 19g, apocynum leaves 31g, gastrodia elata 24g, panax notoginseng 31g, turmeric 34g, short ground tea 28g, green bark 21g and bergamot 16g, mix them in an ultrafine pulverizer for 40 minutes, and The pulverized powder was dissolved in 2000g of ethanol with an alcohol concentration of 95%, soaked for 18 hours, slowly percolated at a rate of 2ml per minute by percolation method, collected percolation liquid, concentrated under reduced pressure to 1 / 10 of the original volume Around, centrifuge at 15000rpm to obtain the supernatant, pass the obtained supernatant through the D101 type macroporous resin column for adsorption, first wash it with 2000g ...

Embodiment 2

[0079] Embodiment 2 Acute toxicity test:

[0080] Get 40 ICR mice (provided by Beijing Weitong Lihua Experimental Animal Technology Co., Ltd.), with a body weight of 25 to 30 grams, dissolve the powder 1 prepared in Example 1 in water, and gavage the mice. Lethal dose (LD 50 ) was experimentally determined, but LD was not detected 50 , so the maximum tolerated dose test was carried out. Result: with maximum concentration (60%), maximum administration, crude drug amount 60g / kg, is equivalent to 300 times (by 75kg) of adult's clinical proposed daily dosage, within seven days, none of mice dies, puts to death mouse anatomy observation each No toxic reaction was found in the organs, and there was no difference between the administration group and the control group mice.

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Abstract

The invention provides a traditional Chinese medicine composition for improving postpartum hypogalactia, which comprises semen vaccariae, fructus liquidambaris, radix astragali, rhizoma polygonati, rhizoma atractylodis macrocephalae, cortex albiziae, radix achyranthis bidentatae, rhizoma kaempferiae, radix rehmanniae praeparata, caulis polygoni multiflori, dianthus superbus, herba plantaginis, folium pyrrosiae, semen coicis, platycodon grandiflorum, folium apocyni veneti, rhizoma gastrodiae, panax notoginseng, radix curcumae longae, Japanese ardisia herb, pericarpium citri reticulatae viride and citrus chirocarpus. The traditional Chinese medicine composition can obviously promote lactescence, increase lactation yield and reduce milk supply; compared with the Western medicine, the traditional Chinese medicine composition takes effect quickly and reduces the efficacy of the toxic and side effects, so that the symptom of postpartum hypogalactia can be treated well, the breast feeding is conductive to implementation, and the growth and development of infants can be promoted.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition for improving postpartum hypogalactia. Background technique [0002] Breast milk is the most ideal natural food for babies, rich in nutrients, easy to digest and absorb, and has the highest bioavailability. Breast milk is rich in protein, secretory immunoglobulin, lactoferrin, white blood cells, lysozyme and antibacterial factors. These substances are very important for infants to defend against infection and can prevent allergies. Breastfeeding is an important means of promoting eugenics. [0003] The puerpera has little or no milk during breastfeeding, and those who are not enough or even unable to feed the baby are called postpartum hypogalactia, and postpartum hypogalactia mostly occurs 2 to 15 days after delivery. The secretion of milk is related to the spirit, emotion, nutritional status, rest and labor of th...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9066A61K9/08A61K9/14A61K9/16A61K9/48A61P15/14
Inventor 姜清华姜妮妮赵丽华
Owner 钟山县红花镇中心卫生院
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