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Chinese medicinal preparation for treating insomnia, method for preparing Chinese medicinal preparation for treating insomnia and application of Chinese medicinal preparation for treating insomnia

A technology of traditional Chinese medicine preparations and insomnia, which is applied in the direction of medical formulas, medical preparations containing active ingredients, and drug combinations. Effect

Active Publication Date: 2013-01-30
NANJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0013] The above-mentioned traditional Chinese medicines for treating insomnia have large prescriptions and many flavors, and most of them are decoctions, which are inconvenient to use. The market is in urgent need of a kind of effective and easy-to-use Chinese medicine preparation for treating insomnia

Method used

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  • Chinese medicinal preparation for treating insomnia, method for preparing Chinese medicinal preparation for treating insomnia and application of Chinese medicinal preparation for treating insomnia
  • Chinese medicinal preparation for treating insomnia, method for preparing Chinese medicinal preparation for treating insomnia and application of Chinese medicinal preparation for treating insomnia
  • Chinese medicinal preparation for treating insomnia, method for preparing Chinese medicinal preparation for treating insomnia and application of Chinese medicinal preparation for treating insomnia

Examples

Experimental program
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Effect test

Embodiment 1

[0036] Stir-fry jujube seed 100g, raw schisandra 400g, stir-fry malt 100g, lily 450g, poria cocos 100g, add 6 times the amount of 95% ethanol and extract twice, each time for 1.0 hour, filter, combine the alcohol extracts, recover the ethanol under reduced pressure and Concentrated to no alcohol. Add 6 times the amount of water to the dregs and extract twice, 1 hour each time, combine the decoction, concentrate the decoction to 0.2g / ml equivalent to the weight of the medicinal material, centrifuge, combine the supernatant with the above-mentioned alcohol extraction concentrate, and concentrate at 50°C To a relative density of 1.15 (50°C), vacuum-dry under reduced pressure to obtain 560 g of dry extract powder, take appropriate amount of extract powder, soybean oil, beeswax, and soybean lecithin, and make the contents of soft capsules, prepare the rubber skin, and make soft capsules.

Embodiment 2

[0038] Stir-fry jujube seed 150g, raw schisandra 350g, stir-fry malt 150g, lily 400g, poria cocos 150g, add 15 times the amount of 80% ethanol for two reflux extractions, each time for 2.0 hours, filter, combine the alcohol extracts, recover the ethanol under reduced pressure and Concentrated to no alcohol. Add 10 times the amount of water to the dregs and extract twice, 1.5 hours each time, combine the decoction, concentrate the decoction to 0.5g / ml equivalent to the weight of the medicinal material, centrifuge, combine the supernatant with the above-mentioned alcohol extraction concentrate, and concentrate at 70°C To a relative density of 1.12 (50 ° C), vacuum drying under reduced pressure to obtain 328.87 g of dry extract powder. Add appropriate amount of dextrin to the extract powder, mix well, carry out wet granulation, dry (50°C-60°C), divide into capsules, and obtain 1000 hard capsules.

Embodiment 3

[0040] Stir-fry Suanzaoren 200g, raw Schisandra chinensis 300g, stir-fry malt 200g, lily 350g, Poria cocos 200g, add 18 times the amount of 85% ethanol to reflux twice for 1.0 hours each time, filter, combine the alcohol extracts, recover the ethanol under reduced pressure and Concentrated to no alcohol. Add 15 times the amount of water to the dregs and extract twice, 2 hours each time, combine the decoction, concentrate the decoction to 0.45g / ml equivalent to the weight of the medicinal material, centrifuge, combine the supernatant with the above-mentioned alcohol extraction concentrate, and concentrate at 60°C To a relative density of 1.10 (50°C). Dry under reduced pressure and vacuum to obtain 0.65kg dry extract powder. Take the extract powder, add sugar powder, and dextrin in an appropriate amount, mix well, carry out wet granulation, and dry (50°C-60°C) to obtain 1000g of granules, which are packaged separately.

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Abstract

The invention discloses a Chinese medicinal preparation for treating insomnia and method for preparing the Chinese medicinal preparation for treating insomnia. The preparation is prepared from fried spina data seed, raw schisandra chinensis, fried fructus hordei germinatus, lilium brownie and poria, the medicinal materials are extracted with ethanol, extract is recycled under a reduced pressure until no ethanol smell, medicinal dregs are decocted with water, the decoction is concentrated and centrifuged, supernatant liquor is continuously concentrated and is mixed with ethanol extracted concentrated liquor, the mixture is concentrated and dried to form extract powder, and an appropriate mount of adjuvants or flavoring agents is added in the extract powder to produce granules, capsules, tablets or pills. Pharmacological tests show that the Chinese medicinal preparation has a good treatment effect on insomnia, and has the effects of relaxing mind and soothing the nerves.

Description

technical field [0001] The invention relates to a traditional Chinese medicine preparation and a preparation method, in particular to a traditional Chinese medicine preparation for treating insomnia made from Chinese medicinal materials, a preparation method and application thereof. Background technique [0002] With the increasingly fierce social competition, the acceleration of people's work and life rhythms, and changes in lifestyles, the incidence of insomnia continues to increase, and it has become more and more common and frequently occurring sleep disorders in modern life. According to a statistical data released by the Ministry of Health of my country, the number of patients with insomnia in my country has reached 1.2 million to 2.4 million. [0003] Long-term severe insomnia can have adverse effects on the body and mind. In children, the secretion of growth hormone is blocked, which affects the growth and development of the body; in adults, the sympathetic nerve fu...

Claims

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Application Information

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IPC IPC(8): A61K36/8998A61P25/20
Inventor 陆兔林毛春芹狄留庆李林季德殷放宙徐佳佳单鑫
Owner NANJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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