Electron spray ionization (ESI) source and controllable high-voltage direct current power supply for ESI source

Abstract

The invention discloses a controllable high-voltage direct current power supply for an ESI source. The controllable high-voltage direct current power supply comprises an oscillating module, a switching module, a boosting module, a voltage-multiplying rectifying module, a filtering module and an output module, wherein the oscillating module is used for conducting self-oscillation and generating switching signals, the switching module is used for conducting alternate connection under the control of switching signals to output initial alternating voltage, the boosting module is used for boosting the initial alternating voltage to obtain second alternating voltage, the voltage-multiplying rectifying module is used for boosting the second alternating voltage according to a preset multiple and rectifying the boosted voltage to output direct voltage, the filtering module is used for filtering the direct voltage, and the output module is used for outputting the filtered direct voltage. The invention also discloses the ESI source. According to the controllable high-voltage direct current power supply and the ESI source, the high voltage and a strong electric field are provided for the ESI source, so that the ionizing efficiency of samples and the transmission efficiency of produced ions can be greatly improved.

Description

technical field [0001] The invention relates to the technical field of mass spectrometers, in particular to an ESI ion source and a controllable high-voltage DC power supply for the ESI ion source. Background technique [0002] A mass spectrometer, also known as a mass spectrometer, is an instrument used to separate and detect different isotopes. Specifically, a mass spectrometer is a type of instrument that separates and detects material composition according to the mass difference of material atoms, molecules or molecular fragments based on the principle that charged particles can be deflected in an electromagnetic field. [0003] A mass spectrometer is mainly composed of ion source, ion introduction and ion transmission, mass analyzer, detector and vacuum system. The ion source is an important part of the mass spectrometer. Its function is to ionize the analyzed sample molecules into charged ions, and make these ions converge into an ion beam with a certain geometry and ...

AI Technical Summary

Problems solved by technology

The traditional mass spectrometer lacks real-time control of the electric field of the electrospray ion source, which is not conducive to its optimal adjustment, which will seriously affect the ionization efficiency and even the sensitivity of the mass spectrometer

Images