Methylphenol-containing nano-emulsion disinfectant and its preparation method

A nanoemulsion and disinfectant technology, applied in the direction of disinfectants, botany equipment and methods, biocides, etc., can solve the problems of restricting the development and application of dosage forms, the impact of production and use, and heavy irritating odors, etc., to achieve prolonged disinfection time, clinical convenience, and the effect of reducing irritating odor

Inactive Publication Date: 2013-05-08
HENAN INST OF SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, due to the complex production process of Lysol and the strong pungent smell, its production and use are affected.
On the other hand, as a chemical disinfectant raw material, the development and application of cresol are limited due to its low water solubility and special pungent odor.

Method used

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  • Methylphenol-containing nano-emulsion disinfectant and its preparation method
  • Methylphenol-containing nano-emulsion disinfectant and its preparation method
  • Methylphenol-containing nano-emulsion disinfectant and its preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] (1) Weigh 14.5 g of cresol, 60.5 g of polyoxyethylene ether hydrogenated castor oil (RH40), 3.0 g of isopropyl myristate (IPM) and 22.0 g of distilled water, and set aside;

[0025] (2) Mix the prescribed amount of cresol and polyoxyethylene ether hydrogenated castor oil (RH40), then add isopropyl myristate (IPM) and mix well for later use;

[0026] (3) Use the distilled water of the prescribed amount as the water phase;

[0027] (4) At room temperature, slowly add the above-mentioned distilled water into the system while stirring continuously until a clear and transparent liquid is formed, that is, a cresol-containing nanoemulsion disinfectant with a particle size of 10-100 nm and a clear and uniform appearance is prepared.

Embodiment 2

[0029] (1) Weigh 0.1 g of cresol, 54.0 g of polyoxyethylene ether hydrogenated castor oil (RH40), 6.0 g of isopropyl myristate (IPM) and 39.9 g of distilled water, and set aside;

[0030] (2) Mix the prescribed amount of cresol and polyoxyethylene ether hydrogenated castor oil (RH40), then add isopropyl myristate (IPM) and mix well for later use;

[0031] (3) Use the distilled water of the prescribed amount as the water phase;

[0032] (4) At room temperature, slowly add the above-mentioned distilled water into the system while stirring continuously until a clear and transparent liquid is formed, that is, a cresol-containing nanoemulsion disinfectant with a particle size of 10-100 nm and a clear and uniform appearance is prepared.

Embodiment 3

[0034] (1) Weigh 7.9 g of cresol, 39.5 g of polyoxyethylene ether hydrogenated castor oil (RH40), 4.3 g of isopropyl myristate (IPM) and 48.3 g of distilled water, and set aside;

[0035] (2) Mix the prescribed amount of cresol and polyoxyethylene ether hydrogenated castor oil (RH40), then add isopropyl myristate (IPM) and mix well for later use;

[0036] (3) Use the distilled water of the prescribed amount as the water phase;

[0037] (4) At room temperature, slowly add the above-mentioned distilled water into the system while stirring continuously until a clear and transparent liquid is formed, that is, a cresol-containing nanoemulsion disinfectant with a particle size of 10-100 nm and a clear and uniform appearance is prepared.

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Abstract

The invention relates to a disinfectant and aims to provide a methylphenol-containing nano-emulsion disinfectant having the advantages of good water solubility, small pungent smell, strong disinfection effect and long disinfection effect maintenance time, and its preparation method. The methylphenol-containing nano-emulsion disinfectant is prepared through using the following raw materials, by weight, 0.1-14.5 parts of methylphenol, 30.0-60.5 parts of a surfactant, 0-15.0 parts of a cosurfactant, 2.3-7.5 parts of oil and 22.0-53.0 parts of distilled water. The methylphenol-containing nano-emulsion disinfectant has the advantages of good stability, simple production technology, low production cost and convenience for the scale production.

Description

Technical field: [0001] The invention relates to the technical field of disinfectants, in particular to a cresol-containing nanoemulsion disinfectant and a preparation method thereof. Background technique: [0002] Cresol, also known as cresol, plays a role of sterilization (disinfection) mainly by causing protein denaturation of pathogenic microorganisms, resulting in the cessation of their growth and reproduction. In addition, it can also be used as a surface active substance to damage the cell membrane of bacteria, so that the leakage of cytoplasmic substances and the dissolution of bacteria can kill bacteria. Cresol has a strong bactericidal effect and can kill most reproductive pathogenic bacteria at an appropriate concentration. It is the main functional ingredient of the traditional phenolic disinfectant Lysol (also known as cresol soap solution). However, due to the complex production process of Lysol and its strong pungent odor, its production and use are affected...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A01N25/04A01N31/08A01P1/00
Inventor 杨雪峰任秀娟葛亚明齐永华王自良胡建和陈金山胡萌杜家洋李珊珊袁香丽丁丹霞
Owner HENAN INST OF SCI & TECH
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