Automatic judgment and control for eluant receiving of buckeye extract

An elution process and automatic judgment technology, applied in chemical instruments and methods, solid adsorbent liquid separation, color/spectral characteristic measurement, etc., can solve problems such as poor product quality uniformity, avoid losses and waste, and save labor costs. , to ensure the effect of quality uniformity and stability

Active Publication Date: 2013-07-17
SHANDONG LUYE PHARMA CO LTD
View PDF5 Cites 8 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The invention provides a near-infrared on-line detection method and an automatic control system for the elution process of the extract of the salsa seed in the macroporous resin, which realizes the change of the content of various active ingredients as the monitoring index in the elution process as the

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Automatic judgment and control for eluant receiving of buckeye extract
  • Automatic judgment and control for eluant receiving of buckeye extract
  • Automatic judgment and control for eluant receiving of buckeye extract

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0041] Example 1 Rapid Judgment and Automatic Control of the Starting Point and End Point of Collecting the Eluate in the Purification Process of the Macroporous Resin of the Salsa Seed Extract

[0042] Salazi: place of origin: Hanzhong, Shaanxi, storage number: YC1100301;

[0043] Near-infrared spectrometer: Matrix-F, German Bruker Spectroscopy Instrument Co., Ltd.;

[0044] HPLC chromatograph: 1200Series, Agilent Technologies Co., Ltd.;

[0045] Aescin sodium reference substance: batch number 200402, source: China Institute for the Control of Pharmaceutical and Biological Products.

[0046] (1) Construction of near-infrared on-line detection system

[0047] The macroporous resin near-infrared online detection system mainly includes: (1) resin column, (2) flow regulating valve, (3) flow cell, (4) sampling valve, (5) optical fiber, (6) near-infrared spectrometer, (7) ) computer, (8) DCS control system. Among them, the macroporous resin column bypass is equipped with a flow...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention provides an automatic detection and control method of elusion start points and end points during macroporous resin purification of buckeye extract. An aescin macroporous resin purification near-infrared calibration model is built by using total content of aescin as evaluation index, the calibration model is used in online detection of buckeye extract macroporous resin elusion, and accordingly automatic judgment of elusion start points and end points during macroporous resin purification of buckeye extract is achieved, and automatic control of eluant receiving and receiving stopping is achieved. The method is fast, accurate, high in automation level and the like, manual errors are reduced, the problem that products of different batches are poor in quality uniformity is solved, effective component loss and waste can be avoided effectively, and a new technique is provided for automatic control and process quality control during macroporous resin purification of buckeye extract.

Description

technical field [0001] The invention relates to an automatic control in the production process of Zhongyue, in particular to an automatic judgment and control of the starting point and the end point of the eluate received by the extract of salsa seeds during the elution process of the macroporous resin. Background technique [0002] Aescin is a mixture containing more than 30 kinds of saponins extracted and separated from the Chinese herbal medicine Suluozi. It belongs to the triterpenoid saponins, and aescin A, B, C, and D are its main active ingredients. Salazi comes from the dry mature seeds of Aesculus aesculus or Tianshi Chestnut. It is sweet and warm in nature and returns to the liver and stomach meridian. Its main functions are soothing the liver and regulating qi, harmonizing the stomach and relieving pain. , chest and abdomen distension, epigastric pain. Aescin is the most important active ingredient of the traditional Chinese medicinal material Salazi. Modern medi...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): B01D15/42G01N21/35G01N21/25
Inventor 薛云丽左爱侠刘雪松李世旭范艳丽吴永江王玉静丁海樱吕道敏陈勇孟莹王龙虎栾连军
Owner SHANDONG LUYE PHARMA CO LTD
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap