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Traditional Chinese medicine extract and preparation method thereof

A technology of extracts and natural medicines, applied in drug combinations, pharmaceutical formulas, anti-tumor drugs, etc., can solve the problems of patients with dehydration, acid-base balance imbalance, malnutrition, etc., and achieve enhanced inhibition, increased inhibition, and good synergy The effect of action

Inactive Publication Date: 2014-12-24
阚兆云
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AI Technical Summary

Problems solved by technology

In recent years, with the advent and popularization of chemotherapy drugs such as 5-fluorouracil, taxanes, hydroxycamptothecin, irinotecan, etc., the incidence of chemotherapy-related diarrhea has increased year by year, and if active treatment is not carried out, it is easy to cause Dehydration, malnutrition, serum electrolyte disorder, acid-base balance disorder, etc. in patients not only bring great disadvantages to the recovery of the body, but also bring certain difficulties to periodic chemotherapy. Therefore, effective treatment of chemotherapy-related diarrhea has become a An important part of the overall treatment of cancer patients
[0003]Chemotherapy-associated diarrhea, in terms of its clinical manifestations, belongs to the category of "diarrhea" in traditional Chinese medicine. The research on diarrhea in traditional Chinese medicine is remarkable, but at present There is no Chinese patent medicine that can relieve diarrhea and increase efficacy against cancer chemotherapy

Method used

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  • Traditional Chinese medicine extract and preparation method thereof
  • Traditional Chinese medicine extract and preparation method thereof

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Experimental program
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Embodiment approach

[0030] The first step: preparation of various extracts

[0031] (1) Preparation of Concentrated Extract of Astragalus Radix Seeds Decocted in Water

[0032] According to the compatibility ratio of 1-4:1, take astragalus and radish seeds, soak in distilled water for 1 hour, heat and decoct for 1 hour, filter with silk cloth, add distilled water to the medicine dregs, soak, decoct, and filter in the same way, mix the two filtrates, and heat Concentrate to a small volume, filter with an ultrafiltration membrane, and dry under reduced pressure at 70°C to obtain the obtained product.

[0033] (2) Preparation of astragalus polysaccharide

[0034] Astragalus is crushed, saponin is extracted with 95% ethanol and dried, then distilled water is added, saturated lime water is added drop by drop, the pH value is adjusted, the material is left to stand for 10 minutes to moisten the material, microwave radiation is 1 minute, the interval is 1 minute and then irradiated for 1 minute, and th...

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Abstract

The invention relates to a natural pharmaceutical composition and a preparation method thereof, and application of the natural pharmaceutical composition in preparation of attenuated synergistic medicines in cancer chemotherapy. The natural pharmaceutical composition is composed of radix astragali / radish seed water-decocted concentrated extract, radix astragali polysaccharide and raphanin in a ratio of (6-8):(3-4):(5-8). The composition has excellent curative effects on diarrhoea related to cancer chemotherapy, and meanwhile, has a synergistic action on cancer chemotherapy.

Description

technical field [0001] The present invention relates to a natural medicinal composition, more specifically to a natural medicinal composition composed of astragalus radish decoction concentrated extract, astragalus polysaccharide and radish, the preparation method of the natural medicinal composition and the natural medicinal composition Use of the pharmaceutical composition in preparing medicines for reducing cancer chemotherapy-related diarrhea and synergizing cancer treatment. Background technique [0002] Malignant tumor is one of the main diseases that endanger human survival and health at present. Its treatment methods include surgery, chemotherapy, radiotherapy, and traditional Chinese medicine treatment, and the effect of chemotherapy on tumors is particularly prominent. Chemotherapy drugs used alone or in combination can cause toxic and side effects such as diarrhea in patients. Diarrhea after tumor chemotherapy is also called chemotherapy-associated diarrhea. In r...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/481A61P35/00A61P1/12A61K31/715A61K31/26
Inventor 阚兆云
Owner 阚兆云