Application of rhodiola rosea compound composite in preparing drug for treating duodenal ulcer

A Rhodiola rosea and composition technology, which is applied in the direction of drug combination, medical formula, plant raw materials, etc., can solve the problems of long healing time, high price, and large side effects, so as to ensure drug efficacy, reduce side effects, and have precise compatibility Effect

Active Publication Date: 2013-09-04
CHINA ACAD OF SCI NORTHWEST HIGHLAND BIOLOGY INST
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The current medicines for treating the above diseases are mostly chemical me

Method used

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  • Application of rhodiola rosea compound composite in preparing drug for treating duodenal ulcer

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] Example 1 Preparation of the drug of the present invention

[0023] Take 20g Poria, 15g Dandelion, 15g Yinchen, 15g Atractylodes, 15g Patchouli 10g, Raw Malt 10g, Rhodiola 6g, Cardamom 5g; first add 4 times the amount of water to soak for 10 minutes, then add water to decoct 2 times, each time After 20 minutes, add 10 times the amount of water each time, filter, and combine the decoction to obtain the medicinal decoction of the present invention.

Embodiment 2

[0024] Example 2 Preparation of the drug of the present invention

[0025] Poria cocos 20g, dandelion 15g, Yinchen 15g, atractylodes 15g, patchouli 10g, raw malt 10g, rhodiola 6g, cardamom 5g; decocted 3 times with water, and decocted for 5 minutes with 10 times the amount of water for the first time. Add 8 times the amount of water for the second time to decoct for 10 minutes, add 8 times the amount of water for the third time to decoct for 15 minutes, filter, combine the decoction, concentrate, add appropriate starch, and granulate to obtain the pharmaceutical granules of the present invention.

Embodiment 3

[0026] Example 3 Preparation of the drug of the present invention

[0027] Take 20g of Poria cocos, 15g of dandelion, 15g of cylindromes, 15g of Atractylodes macrocephala, 10g of patchouli, 10g of raw malt, 6g of rhodiola, and 5g of cardamom; first add 10 times the amount of 70% ethanol solution for reflux extraction once, extract 1 hour, filter , The filtrate is reserved, and the filter residue is decocted twice with water, 8 times the amount of water each time, and 20 minutes each time. After combining the ethanol extract and the water decoction, concentrate, then add appropriate amount of microcrystalline cellulose, dextrin and red After the sedum powder is granulated, an appropriate amount of magnesium stearate is added, and the tablet is compressed to obtain the pharmaceutical tablet of the present invention.

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PUM

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Abstract

The invention discloses an application of a rhodiola rosea compound drug in preparing a drug for treating duodenal ulcer. The drug is prepared by the following active ingredients by in parts by weight: 4.2-7.2 parts of rhodiola rosea, 14-26 parts of poria cocos, 10.5-19.5 parts of dandelion, 10.5-19.5 parts of oriental wormwood, 10.5-19.5 parts of bighead atractylodes rhizome, 7-13 parts of patchouli, 7-13 parts of raw malts, and 3.5-6.5 parts of cardamon. The drug is precise and appropriate in compatibility and less in drug flavor, ensures the drug efficacy, reduces side effects, and can effectively treat the duodenal ulcer, and a new administration selection is provided for clinical administration.

Description

Technical field [0001] The invention relates to the use of a rhodiola compound composition in the preparation of a medicine for treating duodenal ulcer. Background technique [0002] Gastric and duodenal ulcers refer to the limited round or oval full-thickness defects of the gastric and duodenal mucosa. The muscular layer of the mucosa is penetrated, and fibrous scars are inevitably left after healing. The surface is a layer of epithelium. Covered, the muscularis mucosa cannot be regenerated. The etiology can be summarized as the self-digestion of gastric mucosa by gastric acid and pepsin or the destruction of gastric mucosal barrier due to various reasons. In recent years, it is believed that the formation of ulcers is also importantly related to Helicobacter pylori infection in the stomach. [0003] Chronic erosive gastritis, also known as verrucous gastritis or acne-like gastritis, generally only has symptoms of indigestion such as fullness after meals, pantothenic acid, belch...

Claims

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Application Information

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IPC IPC(8): A61K36/9064A61P1/04
Inventor 索有瑞韩丽娟叶英
Owner CHINA ACAD OF SCI NORTHWEST HIGHLAND BIOLOGY INST
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