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Yinhuang lung-heat-clearing troche and preparation method thereof

A silver-yellow lung-clearing and tablet technology, which is applied in the directions of pill delivery, pharmaceutical formulations, and medical preparations containing active ingredients, etc., can solve chronic bronchitis cure cycle prolongation, inaccurate dosage, and bitter taste of capsule contents, etc. problems, to achieve the effect of reducing labor costs and equipment costs, reducing usage, and achieving excellent therapeutic effects

Active Publication Date: 2013-09-11
湖南安邦制药股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Moreover, when dealing with children, due to the large size of the capsules, in order to facilitate swallowing, children generally break the capsules and pour out the contents when taking medicine, which may easily cause the contents of the capsules to spill during the opening process. , but also lead to inaccurate dosage, and the taste of the capsule contents is bitter, which makes it difficult for children to take it
[0004] In addition, the current commercially available drugs have unsatisfactory effects on relieving cough, resolving phlegm, and calming asthma, which prolongs the cure period of chronic bronchitis. In addition to the storm of "poisonous capsules" recently, there is an urgent need for an easy-to-take and effective drug replacement product

Method used

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  • Yinhuang lung-heat-clearing troche and preparation method thereof
  • Yinhuang lung-heat-clearing troche and preparation method thereof
  • Yinhuang lung-heat-clearing troche and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] 1) The raw materials are as follows: Tinglizi 180g; Ephedra 112.5g; Bitter almond 135g; Fritillaria 135g; Loquat leaves 135g; ; Citrus aurantium 45g; Gypsum 180g; Licorice 45g.

[0032] 2) Weigh the above-mentioned fourteen traditional Chinese medicines according to the formula, and crush the ephedra into ephedra powder with a particle size of 125 μm, and set aside.

[0033] 3) Mix Tinglizi, bitter almond, Fritillaria fritillaria, Citrus aurantium and Schisandra chinensis to obtain a mixture; add 7 times the amount of ethanol with a mass concentration of 70% to the mixture, turn on the steam to heat and reflux, and turn on the dynamic pump to start adding Pressurization, using the forced pressurized circulation method, the solvent is continuously circulated from top to bottom in the extraction tank, and the flow is leached, so that the active ingredients of the drug around the diffusion interface of the medicinal material quickly diffuse into the solvent, so that the in...

Embodiment 2

[0037] 1) The raw materials are as follows: Tinglizi 1195g; roasted ephedra 120g; bitter almond 150g; Fritillaria 150g; loquat leaves 120g; ; Citrus aurantium 54g; Gypsum 165g; Licorice 54g.

[0038] 2) Weigh the above-mentioned fourteen traditional Chinese medicines according to the formula, and crush the ephedra ephedra into ephedra ephedra powder with a particle size of 130 μm, and set aside.

[0039] 3) Mix Tinglizi, bitter almond, Fritillaria fritillaria, Citrus aurantium and Schisandra chinensis to obtain a mixture; add 5 times the amount of ethanol with a mass concentration of 70% to the mixture, and use Tianjin Zhongxin Pharmaceutical Co., Ltd. at 45°C The continuous dynamic countercurrent extraction equipment provided by the Group Co., Ltd. extracts for 9 hours and filters to obtain the alcohol extract and alcohol extract residue; the obtained alcohol extract is concentrated at 48°C and 0.08Mpa pressure for 2 hours to obtain the alcohol extract (relative to The densi...

Embodiment 3

[0044] 1) The raw materials are as follows: Tinglizi 165g; Ephedra 102g; Bitter almond 120g; Fritillaria 120g; Loquat leaves 150g; Citrus aurantium 36g; raw gypsum 195g; licorice 36g.

[0045] 2) Weigh the above-mentioned fourteen traditional Chinese medicines according to the formula, and crush the ephedra into ephedra powder with a particle size of 122 μm, and set aside.

[0046] 3) Mix Tinglizi, bitter almond, Fritillaria fritillaria, Citrus aurantium and Schisandra chinensis to obtain a mixture; add 6 times the amount of ethanol with a mass concentration of 70% to the mixture, and use Tianjin Zhongxin Pharmaceutical Co., Ltd. at 50°C The continuous dynamic countercurrent extraction equipment provided by the Group Co., Ltd. dynamically and continuously extracts for 8 hours, filters to obtain alcohol extract and alcohol extract residue; concentrates the obtained alcohol extract at 6°C and 0.17Mpa pressure for 4 hours to obtain alcohol extract ( Density relative to water is ...

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Abstract

The invention discloses a yinhuang lung-heat-clearing troche and a preparation method thereof. The yinhuang lung-heat-clearing troche is prepared from the following raw material components in parts by weight: 165 to 1,195 parts of semen lepidii, 102 to 120 parts of ephedra or processed ephedra, 120 to 150 parts of semen armeniacae amarae, 120 to 150 parts of thunberg fritillary bulb, 120 to 150 parts of folium eriobotryae, 81 to 96 parts of folium isatidis, 120 to 150 parts of rhizoma acori graminei, 120 to 150 parts of rhizoma dioscoreae nipponicae, 81 to 96 parts of artemisia rupestris, 120 to 150 parts of folium ginkgo, 36 to 54 parts of fructus schisandrae, 36 to 54 parts of fructus aurantii immaturus, 165 to 195 parts of raw gypsum, and 36 to 54 parts of liquorice. With high contents of amygdalin, synephrine and fritillaria elements, the yinhuang lung-heat-clearing troche provided by the invention has good therapeutic effects on clearing lung and eliminating phlegm and relieving cough and asthma.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine preparations, in particular to a Yinhuang Qingfei tablet and a preparation method thereof. Background technique [0002] Chronic bronchitis is a clinically common and frequently-occurring disease, which can be caused by influenza and belongs to the category of cough in traditional Chinese medicine. Winter and spring are the peak seasons of its attack every year. The disease involves a wide range of regions and a large population base, but there is no obvious regional difference in the incidence rate in various regions, and it is more common in children, middle-aged and elderly people. At present, there are at least 300 million such patients in our country. With the development of the economy, the air pollution in cities is becoming more and more serious. Chronic obstructive pulmonary disease (COPD) represented by chronic bronchitis has become the "No. Killer Four". According to the fo...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8966A61K9/20A61P11/00A61P11/06A61P11/10A61P11/14A61K33/06
Inventor 高尚
Owner 湖南安邦制药股份有限公司
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