Plate-type capillary column, capillary column unit, and chromatography using same

Abstract

The purpose of the present invention is to provide an expandable plate-type capillary column capable of improving the resolution of chromatography by extending a capillary by stacking each plate-type capillary column even if only one type of shape is prepared and also capable of obtaining a measurement method requiring a complicated flow path. The plate-type capillary column comprises: a plate (P) having a first face plate portion (1) and a second face plate portion (2) facing each other; a capillary (6) formed inside the plate (P); a first bottomed hole (11) connected to one end of the capillary (6) and formed so as to open to the first face plate portion (1); and a second bottomed hole (21) connected to the other end of the capillary (6) and formed so as to open to the second face plate portion (2). When viewed from a direction vertical to the first face plate portion (1) or the second face plate portion (2), one or a plurality of through holes (7) passing through the first face plate portion (1) and the second face plate portion (2) are formed on a capillary column first virtual circle (C1) passing the second bottomed hole (21).

Description

technical field [0001] The present invention relates to a flat-plate capillary column for a chromatograph and a capillary column unit using the same. Background technique [0002] Among capillary columns used in chromatography, for example, a capillary column in which a long and thin glass tube is wound into a coil shape is widely known. In recent years, as an alternative to the above-mentioned large capillary column, there is provided a capillary column in which grooves are formed on the surface of a glass plate and can be molded into a small flat plate. [0003] More specifically, as in Patent Document 1 figure 1 As shown, a thin tube is wound in a helical shape on a virtual plane, and the virtual plane is clamped from both sides by two flat circular plates to form a flat capillary column. In addition, the flat capillary column includes: a sample introduction port formed by opening a blind hole from the surface side of the flat plate, and the sample introduction port pas...

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Problems solved by technology

[0008] However, if it is necessary to manufacture two types of flat-plate capillary columns having such different shapes, it will be a major cause of increased production cost accordingly.

In addition, the flat-plate capillary columns described in Patent Document 1 and Patent Document 2 cannot be applied to conventional chromatographs with capillary columns using glass tubes, requiring complex procedures such as backflushing and heart-cutting. The measurement method of the flow path

Therefore, it is practically difficult to replace capillary columns using glass tubes with flat-plate capillary columns.

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