A microfluidic chip analysis platform based on acoustic wave sensor
An acoustic wave sensor and microfluidic chip technology, applied in the field of microfluidic analysis, to achieve the effect of fast and accurate measurement requirements
Inactive Publication Date: 2015-10-28
SUZHOU SASENS CO LTD
View PDF4 Cites 0 Cited by
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
At present, research on microfluidic chips based on acoustic sensors at home and abroad mostly focuses on one or several directions such as the improvement of detection sensor sensitivity, sample processing and mixed reaction, sample control drive, chip processing materials and methods, and integrates related technologies. and proposing a commercially viable analytics platform rarely involves
Method used
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View moreImage
Smart Image Click on the blue labels to locate them in the text.
Smart ImageViewing Examples
Examples
Experimental program
Comparison scheme
Effect test
Embodiment Construction
[0027] The present invention will be described in detail below with reference to the accompanying drawings and in combination with embodiments.
[0028] refer to figure 1 As shown, a microfluidic chip analysis platform based on an acoustic wave sensor, including a peripheral sampling system 1-1, an acoustic wave sensor 1-2, a sensor signal acquisition and processing system 1-3, a platform support component 1-4 and a sampling Chips 1-5.
[0029] The peripheral sampling system 1-1 is driven by a syringe pump, using a three-way valve or a microvalve integrated on the sampling chip 1-5 to control the on-off of the fluid, and the separate sampling system uses a syringe pump to realize the quantification of the sample For the cleaning of pipetting and sample sampling needles, one syringe pump realizes the driving of samples and buffer solutions in the sampling chip, while the integrated sampling system only uses one syringe pump to sequentially realize the above functions.
[0030...
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More PUM
Login to View More Abstract
The invention discloses a micro-fluidic chip analysis platform based on a sonic sensor. The micro-fluidic chip analysis platform comprises five parts, namely the sonic sensor, a sample feeding chip, a temperature control unit, a peripheral sample feeding system, a sensor signal acquiring and processing system and a platform supporting assembly, wherein the multi-channel sonic sensor is bonded with the polymer sample feeding chip by a solvent to meet a high-throughput test of a liquid sample with a micron scale or a millimeter scale; reaction conditions of a fluid are controlled by an integrated or independent temperature control unit; the peripheral sample feeding system is used for automatically realizing functions of driving the sample and a buffering solution in the chip, quantitatively transferring liquid of a sample, washing a sampling needle and the like. The micro-fluidic chip analysis platform based on the sonic sensor integrates technologies such as sonic sensing, magnetic bead immunization and a micro-fluidic chip so as to avoid signal distortion caused by optical factor interferences of a traditional detection method; meanwhile, an immune magnetic bead is combined to meet the rapid and accurate measurement requirements of the complicated sample.
Description
technical field [0001] The invention belongs to the technical field of microfluidic analysis, and specifically relates to a microfluidic chip analysis platform based on an acoustic wave sensor. Background technique [0002] At present, life science and diagnostic applications, especially protein quantification, put forward new requirements for detection sensors and their systems, including higher test sensitivity, faster response speed and miniaturization. Traditional optical testing methods such as ELISA, Western Blot, and Luminex are widely used, but the above-mentioned testing methods are difficult to avoid the possibility of signal distortion due to the interference of optical factors, which makes it difficult to obtain pg-level ultra-high sensitivity during complex sample testing. At the same time, the above test method is very time-consuming, requiring multiple steps of manual operations to obtain test results. [0003] Microfluidic chip technology integrates basic op...
Claims
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More Application Information
Patent Timeline
Login to View More Patent Type & Authority Patents(China)
IPC IPC(8): G01N29/036
Inventor 周连群李传宇姚佳
Owner SUZHOU SASENS CO LTD