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Preparation method of chewing gum for prevention and adjuvant therapy of periodontitis

A kind of auxiliary treatment, chewing gum technology, applied in the direction of chewing gum, food science, application, etc., can solve the problems of reuterin losing antibacterial activity, instability, etc., achieve broad market prospects and development potential, prevent and treat periodontal disease, and treat dental diseases. The effect of Zhou disease

Active Publication Date: 2014-01-01
HUAQIAO UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] Reuterin has excellent properties of inhibiting and killing oral bacteria, but it is unstable itself, so it is directly added to the chewing gum base. Under high temperature operation, Reuterin will lose its antibacterial activity

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0023] The present invention relates to a kind of preparation method of the chewing gum of prevention and auxiliary treatment periodontitis, and described preparation method comprises the following steps:

[0024] Step 10. Heat the raw edible gum base to 80-120°C, stir well, then add edible plasticizer and glycerin humectant under heating condition, after mixing evenly, add sweetener and filler, and continue stirring for 5-10 minutes Stop heating after 1 hour;

[0025] Step 20, when the temperature drops to 50-60°C, extrude and tablet the obtained material to form a chewing gum base sheet with a thickness of 0.5-1 mm;

[0026] Step 30. When the temperature drops to 30-40°C, under the protection of anaerobic atmosphere, evenly sprinkle the freeze-dried bacterial powder of Lactobacillus reuteri on one surface of the chewing gum base sheet, and the said reuteri milk Bacillus freeze-dried bacteria powder The surface coverage quality of the freeze-dried bacteria powder is 0.01-0.1...

Embodiment 1

[0033] Chewing gum base sheet formula: 10% natural rubber, 8% xanthan gum, 10% xylooligosaccharide, 25% xylitol, 35% monoglyceride, 5% glycerin, 6% calcium carbonate, 1% peppermint oil. Mix evenly according to the above formula at 80°C, then cool to 50°C, and press to form a chewing gum base sheet with a thickness of 0.5mm.

[0034] Preparation steps: under the protection of a nitrogen atmosphere at 30°C, spray the freeze-dried powder of Lactobacillus reuteri on the surface of the rubber substrate, and the surface coverage mass is 0.01 g of bacterial powder / square centimeter of the rubber substrate. Cover another chewing gum base sheet with a thickness of 0.5 mm on the Lactobacillus reuteri freeze-dried powder, press and close the upper and lower gum base sheets, and cut to form a finished chewing gum.

Embodiment 2

[0036] Chewing gum base sheet formula: 10% natural rubber, 8% gellan gum, 10% xylooligosaccharide, 15% xylitol, 10% sorbitol, 35% diglyceride, 5% glycerin, 6% calcium carbonate , peppermint oil 1%. Mix evenly at 120° C. according to the above formula, then cool to 60° C., and press into a chewing gum base sheet with a thickness of 1 mm.

[0037] Preparation steps: under the protection of nitrogen atmosphere at 40°C, spray the freeze-dried powder of Lactobacillus reuteri on the surface of the rubber substrate, and the surface coverage mass is 0.04 g of bacterial powder / square centimeter of the rubber substrate. Cover another rubber substrate with a thickness of 1 mm on the Lactobacillus reuteri freeze-dried powder, press and close the upper and lower rubber substrates, and cut to form a finished chewing gum.

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Abstract

The invention provides a preparation method of a chewing gum for the prevention and adjuvant therapy of periodontitis. The preparation method is characterized by comprising the steps of uniformly stirring an edible gum base, an edible plasticizer, a glycerol humectant, a sweetening agent and a filling agent at 80-120 DEG C; when the temperature is reduced to 50-60 DEG C, extruding and tabletting the obtained material to form chewing gum base pieces; when the temperature is reduced to 30-40 DEG C, under the protection of an anaerobic atmosphere, uniformly spreading the freeze-dried powder of lactobacillus reuteri to one surface of one chewing gum base piece, and covering another chewing gum base piece, namely clamping the freeze-dried powder of lactobacillus reuteri in two chewing gum base pieces; finally tabletting and forming to obtain a finished product of the chewing gum. By adopting the preparation method provided by the invention, the prepared chewing gum can achieve the aims of cleaning the mouth cavity and preventing and treating periodontal diseases; moreover, the storage time is long, and active substances are not easily inactivated.

Description

【Technical field】 [0001] The invention relates to a preparation method of chewing gum for prevention and auxiliary treatment of periodontitis. 【Background technique】 [0002] Dental health is an important aspect of physical health. Gingivitis, periodontitis, and dental caries are common clinical diseases and frequently-occurring diseases, which not only seriously affect human dental health, but also induce many other diseases. Periodontitis refers to chronic inflammation that occurs in the gums, periodontal ligament, cementum, and alveolar bone. Most cases develop from long-standing gingivitis, forming periodontal pockets and alveolar bone absorption symptoms. Periodontitis is an infectious disease, that is, bacteria play a decisive role in the occurrence and development of periodontitis. Bacteria attach to teeth or soft tissues to form plaques, where they proliferate, develop, and produce many toxic factors, causing redness and swelling of the gums, bleeding, damage to th...

Claims

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Application Information

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IPC IPC(8): A23G4/12
Inventor 陈国林檬
Owner HUAQIAO UNIVERSITY
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