Priming anticoagulant line for blood extraction

An anticoagulant and anticoagulant technology, which can be used in blood circulation treatment, suction equipment, etc., and can solve the problem that the donor is not clinically significant.

Active Publication Date: 2014-02-05
GRIFOLS
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

Although the poor quality constituted by pre-filled anticoagulant in the line prior to collection is negligible for a single supply a

Method used

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  • Priming anticoagulant line for blood extraction
  • Priming anticoagulant line for blood extraction
  • Priming anticoagulant line for blood extraction

Examples

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Embodiment

[0064] can be used for platelet-deficient plasma collection A plasma collection system (Haemonetics, Braintree, MA) demonstrates the non-limiting examples described herein. The U.S. Food and Drug Administration regulates the amount of blood collected from a donor used in blood component transfusions and is regulated in 21 C.F.R. §640.65. See Table 1. This regulation refers to the regulation (memorandum) from Kathryn C. Zoon, Director, FDA Center for Biologics Evaluation and Research, Volume Limits for Automated Collection of Source Plasma (November 4, 1992); and see Compliance Policy Guide §252.110 Volume Limits for Automated Collection of Source Plasma (March, 6, 2000). The amount of anticoagulant (4% sodium citrate solution) added to whole blood was based on the ratio of anticoagulant to anticoagulated blood. The Center for Biologics Evaluation and Research (CBER) developed a nomogram that details the maximum volume of plasma that can be collected from a donor based on t...

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Abstract

A description is given of a method and devices for reducing anticoagulant dilution of the blood components obtained during blood extraction. This is achieved by means of the priming of the apheresis apparatus with anticoagulant from the anticoagulant reservoir up to a point close to the venous access device located in the extraction/return tube.

Description

technical field [0001] Described herein are devices and methods for collecting blood components. More specifically, the methods and devices described herein relate to reducing the dilution of collected blood components during blood collection by anticoagulants used to prime the collection prior to the start of the collection process System: priming anticoagulant. Background technique [0002] Component transfusion is the process of collecting and separating individual blood components from whole blood (temporarily drawn from a donor). Generally, whole blood is drawn through a needle inserted into a vein in the donor's arm; anticoagulants are added to the blood, and it is pumped into a separator such as a centrifuge jar. After whole blood is separated into its various components based on physical properties such as density (eg, red blood cells, white blood cells, platelets, and plasma), one or more components can be removed from the centrifuge canister. The remaining compo...

Claims

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Application Information

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IPC IPC(8): A61M1/38
CPCA61M2001/3644A61M1/3496A61M1/3643A61M1/3644A61M1/3672A61M1/38
Inventor 格雷格·弗莱克斯曼
Owner GRIFOLS
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