Wind-dispelling and hair-restoring alopecia areata pellet

A micropill and alopecia areata technology, which is applied in the field of alopecia areata pills (micropills) and its preparation, can solve problems such as complexity, poor clinical application effect, and affecting the properties of traditional Chinese medicine compounds, and achieve the effect of avoiding volatilization

Active Publication Date: 2014-02-12
ZHEJIANG WECOME MEDICINE IND
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The improvement of the compound dosage form of traditional Chinese medicine is particularly complicated. If it is not handled properly, it will affect the properties of the compound Chinese medicine, and the clinical application effect is not good.

Method used

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  • Wind-dispelling and hair-restoring alopecia areata pellet
  • Wind-dispelling and hair-restoring alopecia areata pellet
  • Wind-dispelling and hair-restoring alopecia areata pellet

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0041] Embodiment 1: Alopecia areata pellets

[0042] The formula is: 108 parts by weight of rehmannia glutinosa, 108 parts by weight of rehmannia glutinosa, 108 parts by weight of Polygonum multiflorum, 60 parts by weight of angelica, 60 parts by weight of salvia miltiorrhiza, 60 parts by weight of white peony, 60 parts by weight of schisandra, 30 parts by weight of notopterygium, and 30 parts by weight of papaya , 30 parts by weight of starch.

Embodiment 2

[0043] Embodiment 2: Alopecia areata pellets

[0044] The formula is: 148 parts by weight of rehmannia glutinosa, 148 parts by weight of rehmannia glutinosa, 148 parts by weight of Polygonum multiflorum, 98 parts by weight of angelica, 98 parts by weight of salvia miltiorrhiza, 98 parts by weight of white peony, 98 parts by weight of schisandra, 50 parts by weight of notopterygium, and 50 parts by weight of papaya ; 50 parts by weight of starch.

Embodiment 3

[0045] Embodiment 3: preparation process

[0046] 1. Weigh the raw materials according to the formula in Example 2, wash, cut, and dry the raw materials. The drying conditions are 60-70°C, and the moisture content is controlled to no more than 5%;

[0047] 2. Angelica sinensis, salvia miltiorrhiza, rehmannia glutinosa, and Radix Polygoni Multiflori are weighed by weight, mixed, and pulverized into powder I of 100 μm;

[0048] 3. Freeze Rehmannia glutinosa to -25°C, and then grind Rehmannia glutinosa to 1000 μm powder II at -10°C, and then dry it under vacuum;

[0049] 4. Crush notopterygium into 1000 μm powder III;

[0050] 5. Mix Schisandra chinensis and Radix Paeoniae Alba, then pulverize into 1000 μm powder IV;

[0051] 6. Crush the papaya into a powder V of 100 μm;

[0052] 7. Mix powder II, powder III, and powder IV evenly, and then continue to crush into powder VI of 100 μm;

[0053] 8. Mix powder I, powder V, and powder VI, add pharmaceutical excipients, and mix eve...

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Abstract

The invention relates to a pellet preparation, and in particular relates to a wind-dispelling and hair-restoring alopecia areata pellet. The pellet comprises the following components in parts by weight: 148 parts of rehmannia, 148 parts of prepared rehmannia, 148 parts of prepared polygonum multiflorum, 98 parts of Chinese angelica, 98 parts of salvia miltiorrhiza, 98 parts of white peony root, 98 parts of schisandra chinensis, 50 parts of notopterygium root, 50 parts of pawpaw, and 10-1,000 parts of medical auxiliaries. The invention also relates to a preparation method of the alopecia areata pill (pellet). By adopting the method, alopecia areata pellet with diameter of 3.5-4mm is prepared from the traditional alopecia areata pill, so that the alopecia areata pellet is stable in quality and remarkable in drug effect, has extremely good fluidity and dissolution, and is suitable for clinical application.

Description

technical field [0001] The invention relates to a pellet preparation, in particular to an alopecia areata pill (pellet) for expelling wind and promoting hair growth and a preparation method thereof. Background technique [0002] The effects of Alopecia areata pills are: nourishing liver and kidney, nourishing blood and growing hair. It is used for oily wind caused by deficiency of liver and kidney, blood deficiency and excess wind. Symptoms include hair loss in flakes, often accompanied by dizziness, insomnia, dizziness, tinnitus, soreness of waist and knees; alopecia areata sees the above syndromes. Contains the following 9 herbs: Rehmannia glutinosa, Rehmannia glutinosa, Polygonum multiflorum, Angelica, Salvia miltiorrhiza, Radix Paeoniae Alba, Schisandra chinensis, notopterygium, papaya. [0003] In the prior art, the preparation process of the drug is direct processing of crude drug powder, which has defects such as large oral dose and slow disintegration. Micropills h...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/16A61K36/804A61P17/14
Inventor 刘忠良
Owner ZHEJIANG WECOME MEDICINE IND
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