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Traditional Chinese medicinal composition for preventing and treating female climacteric syndrome

A composition and syndrome technology, applied in the direction of drug combination, disease, medical formula, etc., can solve the inconvenience of patients and other problems, and achieve the effect of reducing the number of times of taking, prolonging the action time, and prolonging the action time

Active Publication Date: 2014-02-12
GUIYANG XINTIAN PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although this capsule has the above benefits, it needs to be taken three times a day, which brings inconvenience to patients who need long-term administration

Method used

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  • Traditional Chinese medicinal composition for preventing and treating female climacteric syndrome
  • Traditional Chinese medicinal composition for preventing and treating female climacteric syndrome
  • Traditional Chinese medicinal composition for preventing and treating female climacteric syndrome

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0013] Scutellaria baicalensis 11kg, Poria cocos 6kg, Radix Paeoniae Alba 8kg, Rehmannia glutinosa 3kg, Coptidis 1kg, Donkey-hide gelatin 11kg, Panax notoginseng 3kg were pulverized into coarse powder, extracted twice with 95% ethanol solution, each extraction time was 3 hours, each time the ethanol used The amount is 150kg, and the extract is filtered and concentrated to obtain an extract with a relative density of 1.2 at 40-60°C; take one-third of the extract, add 2kg of starch to make immediate-release granules, pass through a 80-mesh sieve, and pass through a 50-mesh sieve. ℃ blast drying, take two-thirds of the extract, add hypromellose 3kg to make slow-release granules, pass through a 80-mesh sieve, and blow dry at 50°C, mix the above two granules evenly, fill capsules, and prepare Into 100,000 capsule preparations.

[0014] Using double-blind, randomized, controlled outpatient observation method research, 30 subjects were divided into two groups, the new drug group: tak...

Embodiment 2

[0032] Scutellaria baicalensis 11kg, Poria cocos 6kg, Radix Paeoniae Alba 8kg, Rehmannia glutinosa 8kg, Coptis chinensis 2kg, Donkey-hide gelatin 7kg, Panax notoginseng 1kg were pulverized into coarse powder, extracted twice with 75% ethanol solution, each extraction time was 5 hours, each time the ethanol used The amount is 150kg, and the extract is filtered and concentrated to obtain an extract with a relative density of 1.2 at 40-60°C; take one-third of the extract, add 2kg of starch to make immediate-release granules, pass through a 80-mesh sieve, and pass through a 50-mesh sieve. ℃ blast drying, take two-thirds of the extract, add hypromellose 3kg to make slow-release granules, pass through a 80-mesh sieve, and blow dry at 50°C, mix the above two granules evenly, fill capsules, and prepare Into 100,000 capsule preparations.

[0033] By the same method as Example 1, the medicine of Example 2 is clinically observed, and the results are as follows

[0034]

[0035] Concl...

Embodiment 3

[0037]Scutellaria baicalensis 11kg, Poria cocos 6kg, Radix Paeoniae Alba 8kg, Rehmannia glutinosa 8kg, Coptis chinensis 2kg, Donkey-hide gelatin 7kg, Panax notoginseng 1kg were pulverized into coarse powder, extracted twice with 75% ethanol solution, each extraction time was 5 hours, each time the ethanol used The amount is 150kg, and the extract is filtered and concentrated to obtain an extract with a relative density of 1.15 at 40-60°C; take one-third of the extract, add 2kg of starch to make immediate-release granules, pass through a 80-mesh sieve, and pass through a 50-mesh sieve. ℃ blast drying, take two-thirds of the extract, add hypromellose 3kg to make slow-release granules, pass through a 80-mesh sieve, and blow dry at 50°C, mix the above two granules evenly, fill capsules, and prepare Into 100,000 capsule preparations.

[0038] By the same method as Example 1, the medicine of Example 3 is clinically observed, and the results are as follows:

[0039]

[0040] Conc...

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Abstract

The invention provides a traditional Chinese medicinal composition for preventing and treating female climacteric syndrome and a preparation method of the traditional Chinese medicinal composition. Effective ingredients for preparing the traditional Chinese medicinal composition for preventing and treating female climacteric syndrome consist of the following raw materials in parts by weight: 2-8 parts of prepared rehmannia root, 1-2 parts of coptis chinensis, 3-9 parts of white paeony root, 7-11 parts of colla corii asini, 11-18 parts of scutellaria baicalensis, 2-6 parts of Tuckahoe and 1-3 parts of pseudo-ginseng. The traditional Chinese medicinal composition includes quick-release granules and slow-release granules; and a clinical trial proves that the traditional Chinese medicinal composition has an obvious clinical effect on female climacteric syndrome and is convenient to take once a day.

Description

technical field [0001] The invention relates to a traditional Chinese medicine preparation, in particular to a traditional Chinese medicine formula and a preparation method for preventing and treating women's climacteric syndrome. Background technique [0002] Menopausal syndrome refers to a series of syndromes mainly caused by autonomic dysfunction and metabolic disorders caused by the gradual decline or loss of ovarian function in women during perimenopause or after, resulting in a decrease in estrogen levels. Menopause refers to women's perimenopause, usually between 45 and 55 years old, and the average age of menopause is 49 years old. If menopause occurs, it belongs to ovarian function decline, followed by menopausal symptoms such as hot flashes, hyperhidrosis, anxiety and depression, upset and irritability. Generally, when the menopause is abnormal, the symptoms have already begun to appear, which can last for 2-3 years after menopause. Only a few people can reduce or...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/804A61K9/48A61P15/12A61K35/36
Inventor 段燕康岳维芸李瑞霞向澜黄晓昱张杰
Owner GUIYANG XINTIAN PHARMA CO LTD
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