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Chinese medicinal composition for fungal infection of skin and preparation method thereof

A skin fungus and composition technology, applied in the field of traditional Chinese medicine, can solve the problems of easy recurrence, difficult fungi, and inability to cure, and achieve the effect of single chemical property, high purity, and improved bactericidal function

Active Publication Date: 2014-02-19
XINXIANG MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Due to the large difference in the chemical properties of various antibacterial active ingredients in traditional Chinese medicine preparations made from Chinese herbal medicines, it is difficult to act on fungi in the deep layer of the skin.

Method used

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  • Chinese medicinal composition for fungal infection of skin and preparation method thereof
  • Chinese medicinal composition for fungal infection of skin and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] Prescription composition:

[0022] Toosendan 2kg, Phellodendron 2kg, Safflower 1.5kg and Artemisia argyi 3kg

[0023] Preparation method of ointment:

[0024] 1) The safflower is crushed to 120 mesh, and the remaining herbs are crushed to 60 mesh to obtain medicinal powders of various medicinal materials;

[0025] 2) Extract 3 times with 10% glacial acetic acid, soak for 7 days for the first time, soak for 3 days for the second and third times, filter and concentrate to a relative density of 1.20-1.30 (25°C) to obtain a concentrated solution .

[0026] 3) Mix the concentrated Chinese medicine composition, a mixture of 85% vaseline and 15% lanolin, paraben, and 10% glacial acetic acid in a ratio of 3:5:1:1 to make a uniform skin for external use ointment.

experiment example 1

[0027] Experimental example 1: the clinical trial of antibacterial Chinese medicine composition of the present invention

[0028] 1. Clinical data

[0029] Case selection: select 50 cases of beriberi patients: 25 males and 25 females; 42 cases of tinea corporis, 20 males and 22 females; 45 cases of prurigo, 30 males and 15 females. , the general clinical data are shown in Table 1

[0030] Table 1. General clinical data

[0031]

[0032] 2. Treatment

[0033] 2.1 The ointment of Example 1 of the present invention is evenly applied to the affected part, and the dressing is changed every 2 to 3 days, and 5 days is a course of treatment.

[0034] 3. Curative effect standard

[0035] Cure: no itching, inflammation disappears; skin lesions remain intact, leaving no traces.

[0036] Effective: There is slight redness and swelling, and the area of ​​the affected area is reduced by more than 2 / 3;

[0037] Invalid: The original symptoms have not changed.

[0038] 4. Treatment ...

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Abstract

The invention relates to a Chinese medicinal composition for fungal infection of skin. The Chinese medicinal composition is prepared from the following raw medicinal materials in parts by weight: 10-30 parts of szechwan Chinaberry fruit, 10-30 parts of golden cypress, 5-25 parts of safflower and 15-40 parts of Chinese mugwort leaf. The Chinese medicinal composition belongs to an anti-fungal infection medicine for external use, is safe to use and has an obvious effect.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for skin fungal infection and a preparation method thereof, belonging to the field of traditional Chinese medicines. Background technique [0002] With the wide application of high-efficiency broad-spectrum antibiotics and the increasing number of patients with diabetes and acquired immunodeficiency syndrome, the incidence of fungal infections is on the rise. The medical community has been committed to finding effective and safe antifungal drugs. Chinese herbal medicine is one of the precious wealth in the motherland's medical treasure house. There are many active ingredients in Chinese herbal medicine with strong activity and low toxicity, which have certain antibacterial and bactericidal effects on common pathogenic bacteria. Research and development of various antifungal traditional Chinese medicines is of great significance to solving the problem of drug-resistant strains. [000...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/756A61P31/10A61P17/00
Inventor 詹合琴黄锋崔泰震张慧孙娟张文熙刘凤岐
Owner XINXIANG MEDICAL UNIV
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