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Medicinal preparation for treating epidemic keratoconjunctivitis

A pharmaceutical preparation and keratoconjunctivitis technology, applied in the field of pharmaceutical preparations for the treatment of epidemic keratoconjunctivitis, can solve the problems of ineffective anti-inflammatory drugs, easily causing steroid cataracts, drug resistance, etc., and achieve clinical application value High, stable therapeutic effect, high safety effect

Inactive Publication Date: 2014-04-16
QINGDAO HUAREN TECH INCUBATOR
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The medical treatment of this disease is generally to use anti-inflammatory drugs or hormone drugs. The effect of anti-inflammatory drugs is not significant and there is drug resistance. Complications with serious consequences for the patient

Method used

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  • Medicinal preparation for treating epidemic keratoconjunctivitis
  • Medicinal preparation for treating epidemic keratoconjunctivitis
  • Medicinal preparation for treating epidemic keratoconjunctivitis

Examples

Experimental program
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Effect test

preparation example Construction

[0057] The present invention also provides the preparation method of above-mentioned pharmaceutical preparation, specifically:

[0058] The first step is to mix the components of the raw materials by weight to obtain a mixture, reflux extraction with ethanol with an alcohol concentration of 80% to 90% for 3 to 5 times, filter, combine the filtrates, and concentrate under reduced pressure to a relative density of 1.20 ~1.23 (60°C) paste, the amount of ethanol added each time is 2 to 4 times the mass of the mixture, then dried and crushed into powder, and the crushed powder is added 3 to 5 times the mass Dissolve in a certain amount of water, add 5% to 10% sodium hydroxide relative to the powder mass under stirring to help dissolve, adjust the pH value to 7 to 8, filter, add sulfuric acid with a concentration of 10% to adjust the pH value to 3 to 4, and stand still for 2 ~4 hours, filter, the filtrate is concentrated under reduced pressure into a paste with a relative density of...

Embodiment 1

[0062] Embodiment 1 eye drops 1

[0063] 30g of Fangfeng, 40g of Senecio, 25g of Mint, 20g of Goose Herbivore, 40g of Cassia, 25g of Saffron, 25g of Morus alba, 50g of Radix Isatidis, 40g of Cuscuta, 30g of Qinpi, 25g of Eclipta, 30g of Liedong , Honeysuckle 40g, Budisma 30g, Plantain 20g, Nepeta 25g, Ligustrum lucidum 40g, Coptis 70g, Shayuanzi 30g, Chinese yam 40g, Mix 25g of stock, 25g of Prunella vulgaris, 30g of mulberry seed, 40g of green weed, 30g of raspberry, 30g of Gujingcao, 35g of orchid vanilla and 30g of ghost needle grass to obtain a mixture, and use 3kg of ethanol with an alcohol concentration of 90% each time Reflux extraction 4 times, filter, combine the filtrates, concentrate under reduced pressure to a paste with a relative density of 1.20 (60°C), then dry and pulverize into powder, and dissolve the pulverized powder with 4 amounts of water relative to its mass , under stirring, add 5% sodium hydroxide relative to the powder mass to help dissolve, adjust ...

Embodiment 2

[0064] Embodiment 2 eye drops 2

[0065] 28g of Fangfeng, 38g of Senecio, 23g of Mint, 18g of Goose Herbivore, 38g of Cassia, 23g of Saffron, 23g of Morus alba, 48g of Radix Isatidis, 38g of Cuscuta, 28g of Qinpi, 23g of Eclipta, 28g of Liedong , Honeysuckle 38g, Budisma 28g, Plantain 18g, Nepeta 23g, Ligustrum lucidum 38g, Coptis 68g, Shayuanzi 28g, Chinese yam 38g, Mix 23g of stock, 23g of Prunella vulgaris, 28g of mulberry seeds, 38g of green weeds, 28g of raspberries, 28g of Gujingcao, 33g of orchid vanilla and 28g of ghost needles to obtain a mixture, and use 3kg of ethanol with an alcohol concentration of 90% each time Reflux extraction 4 times, filter, combine the filtrates, concentrate under reduced pressure to a paste with a relative density of 1.20 (60°C), then dry and pulverize into powder, and dissolve the pulverized powder with 4 amounts of water relative to its mass , under stirring, add 5% sodium hydroxide relative to the powder mass to help dissolve, adjust t...

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Abstract

The invention provides a medicinal preparation for treating epidemic keratoconjunctivitis. The preparation comprises crude medicines such as saposhnikovia divaricata, senecio scandens ham, mint, centipeda minima, concha haliotidis, stigma croci, white mulberry root bark, isatis roots, semen cuscutae, ash bark, eclipta, liriope spicata, honeysuckle, buddleja officinalis, plantain herbs, schizonepeta, glossy privet fruits, coptis chinensis, flatstem milkvetch seeds, Chinese yams, polygonum aviculare, selfheal spike, fructus broussonetiae, feather cockscomb seeds, raspberries, pipewort, caryopteris incana and bidens bipinnata. The medicinal preparation is low in side effect occurrence rate, stable in treatment effect, reliable, high in safety and higher in clinical application value.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a pharmaceutical preparation for treating epidemic keratoconjunctivitis. Background technique [0002] Epidemic keratoconjunctivitis is a highly contagious, rapid-onset eye disease, mostly caused by adenovirus infection. If treatment is delayed, sequelae will be left. The damage to the cornea can last for several months or years, and even left corneal clouding affects vision. Epidemic keratoconjunctivitis, there may be a history of infection before the disease, and the incubation period is 5 to 7 days. The first eye will be affected first, and the other eye will be affected later, with foreign body sensation, itching, pain, watery mucus discharge, photophobia, tearing . Eyelid conjunctival congestion and edema, a large number of follicles in the conjunctival vault, subconjunctival hemorrhage and pseudomembrane formation may occur. After 1 to 2 weeks of ons...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/896A61P27/02A61P31/20A61K35/56A61K35/618
Inventor 孙霞
Owner QINGDAO HUAREN TECH INCUBATOR
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