Eye drops for epidemic keratoconjunctivitis

A technology of keratoconjunctivitis and eye drops, which is applied in the field of traditional Chinese medicine, can solve the problems of insignificant anti-inflammatory drugs, easy to cause steroid cataract, and drug resistance, and achieve high clinical application value, stable therapeutic effect, High safety effect

Inactive Publication Date: 2016-02-24
殷志杰
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The medical treatment of this disease is generally to use anti-inflammatory drugs or hormone drugs. The effect of anti

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Example Embodiment

[0022] The present invention also provides the preparation method of the above-mentioned eye drops, specifically:

[0023] In the first step, the components of each raw drug are mixed by weight to obtain a mixture, which is extracted 3 to 5 times with ethanol having an alcohol concentration of 80% to 90% by reflux, filtered, combined with the filtrates, and concentrated under reduced pressure to a relative density of 1.20 ~1.23 (60°C) paste, the amount of ethanol added each time is 2 to 4 times the mass of the mixture, then dried, and pulverized into powder, and the pulverized powder is added 3 to 5 times its mass. Amount of water to dissolve, add 5% to 10% sodium hydroxide relative to the mass of the powder to help dissolve under stirring, adjust the pH to 7 to 8, filter, add 10% sulfuric acid to adjust the pH to 3 to 4, stand at 2 ~4 hours, filtered, the filtrate was concentrated under reduced pressure into a paste with a relative density of 1.29-1.32 (70°C), dried, and pulv...

Example Embodiment

[0027] Example 1 Eye Drops 1

[0028] 30g Fangfeng, 40g Qianliguang, 25g mulberry white peel, 50g borneol, 40g dodder, 30g Qinpi, 25g Eclipta, 30g Ophiopogon japonicus, 40g honeysuckle, 30g Mimeng flower, 20g plantain, 25g Nepeta, female Mixed with 40g of Sadako, 70g of Coptis, 30g of Shayuanzi, 40g of Chinese yam, 25g of Yushu, 25g of Prunella vulgaris, 30g of Eucalyptus Fructus, 40g of Green Seed, 30g of raspberry, 30g of Gujingcao, 35g of Orchid Herb and 30g of Elephant Needle , the mixture was obtained, extracted 4 times with 3 kg of ethanol with an alcohol concentration of 90% each time, filtered, and the filtrate was combined, concentrated under reduced pressure to a paste with a relative density of 1.20 (60 ° C), followed by drying, and pulverized into powder, Dissolve the pulverized powder with 4 amounts of water relative to its mass, add 5% sodium hydroxide relative to the mass of the powder to dissolve under stirring, adjust the pH value to 7, filter, and concentrate...

Example Embodiment

[0029] Example 2 Eye Drops 2

[0030] 28g of windproof, 38g of Qianliguang, 23g of mulberry white skin, 48g of borneol, 38g of dodder, 28g of Qinpi, 23g of Eclipta, 28g of Ophiopogon japonicus, 38g of honeysuckle, 28g of Mimeng flower, 18g of plantain, 23g of Nepeta Mixed with 38g of Sadako, 68g of Coptis, 28g of Shayuanzi, 38g of Chinese yam, 23g of Yushu, 23g of Prunella vulgaris, 28g of Fructus Fructus, 38g of Green Herba, 28g of Raspberries, 28g of Gujingcao, 33g of Orchid Herb and 28g of Elephant Needle , the mixture was obtained, extracted 4 times with 3 kg of ethanol with an alcohol concentration of 90% each time, filtered, and the filtrate was combined, concentrated under reduced pressure to a paste with a relative density of 1.20 (60 ° C), followed by drying, and pulverized into powder, Dissolve the pulverized powder with 4 amounts of water relative to its mass, add 5% sodium hydroxide relative to the mass of the powder to dissolve under stirring, adjust the pH value ...

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PUM

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Abstract

The invention provides eye drops for epidemic keratoconjunctivitis. The eye drops are prepared from radix saposhnikoviae, senecio scandens, mint, centipeda minima, concha haliotidis, crocus sativus, white mulberry root-bark, borneol, semen cuscutae, ash bark, herba ecliptae, liriope spicata, honeysuckle, buddleja officinalis, plantain herbs, schizonepeta, glossy privet fruit, coptis chinensis, flatstem milkvetch seeds, Chinese yam, polygonum aviculare, prunella vulgaris, paper mulberry fruit, feather cockscomb seeds, raspberries, pipewort, common bluebeard herbs and sticktight. The eye drops have few side effects and are stable in treatment effect, reliable, high in safety and high in clinical application value.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to an eye drop for epidemic keratoconjunctivitis. Background technique [0002] Epidemic keratoconjunctivitis has a rapid onset and is mostly caused by adenovirus infection. If treatment is delayed, sequelae will be left. The damage to the cornea can last for several months or years, and even left corneal clouding affects vision. Epidemic keratoconjunctivitis, there may be a history of infection before the disease, and the incubation period is 5 to 7 days. The first eye will be affected first, and the other eye will be affected later, with foreign body sensation, itching, pain, watery mucus discharge, photophobia, tearing . Eyelid conjunctival congestion and edema, a large number of follicles in the conjunctival vault, subconjunctival hemorrhage and pseudomembrane formation may occur. After 1 to 2 weeks of onset, conjunctival inflammation gradually subsides, ...

Claims

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Application Information

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IPC IPC(8): A61K36/896A61K9/08A61P27/02A61P31/20A61K31/045
Inventor 不公告发明人
Owner 殷志杰
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