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Eye drops for epidemic keratoconjunctivitis

A technology of keratoconjunctivitis and eye drops, which is applied in the field of traditional Chinese medicine, can solve the problems of insignificant anti-inflammatory drugs, easy to cause steroid cataract, and drug resistance, and achieve high clinical application value, stable therapeutic effect, High safety effect

Inactive Publication Date: 2016-02-24
殷志杰
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The medical treatment of this disease is generally to use anti-inflammatory drugs or hormone drugs. The effect of anti-inflammatory drugs is not significant and there is drug resistance. Complications with serious consequences for the patient

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0022] The present invention also provides the preparation method of above-mentioned eye drops, specifically:

[0023] The first step is to mix the components of the raw materials by weight to obtain a mixture, reflux extraction with ethanol with an alcohol concentration of 80% to 90% for 3 to 5 times, filter, combine the filtrates, and concentrate under reduced pressure to a relative density of 1.20 ~1.23 (60°C) paste, the amount of ethanol added each time is 2 to 4 times the mass of the mixture, then dried and crushed into powder, and the crushed powder is added 3 to 5 times the mass Dissolve in a certain amount of water, add 5% to 10% sodium hydroxide relative to the powder mass under stirring to help dissolve, adjust the pH value to 7 to 8, filter, add sulfuric acid with a concentration of 10% to adjust the pH value to 3 to 4, and stand still for 2 ~ 4 hours, filter, the filtrate is concentrated under reduced pressure into a paste with a relative density of 1.29 ~ 1.32 (70...

Embodiment 1

[0027] Embodiment 1 eye drops 1

[0028] Fangfeng 30g, Senecio 40g, Morus alba 25g, Borneol 50g, Cuscuta 40g, Qinpi 30g, Eclipta 25g, Ophiopogon japonicus 30g, Honeysuckle 40g, Mimenghua 30g, Plantain 20g, Nepeta 25g, female 40g of Zhenzi, 70g of Coptis chinensis, 30g of Shayuanzi, 40g of Yam, 25g of Cucumber, 25g of Prunella vulgaris, 30g of Mushizi, 40g of Qingshenzi, 30g of Raspberry, 30g of Gujingcao, 35g of Orchid Herb and 30g of Prunella vulgaris , to obtain the mixture, each use alcohol concentration of 90% ethanol 3kg reflux extraction 4 times, filter, combine the filtrate, concentrate under reduced pressure to a paste with a relative density of 1.20 (60°C), then dry and pulverize into powder, Dissolve the pulverized powder with 4% water relative to its mass, add 5% sodium hydroxide relative to the powder mass under stirring to help dissolve, adjust the pH value to 7, filter, and concentrate the filtrate under reduced pressure to a relative density of 1.30 (60 ℃) past...

Embodiment 2

[0029] Embodiment 2 eye drops 2

[0030] Fangfeng 28g, Senecio 38g, Morus alba 23g, Borneol 48g, Cuscuta 38g, Qinpi 28g, Eclipta 23g, Ophiopogon japonicus 28g, Honeysuckle 38g, Mimeng japonica 28g, Plantain 18g, Nepeta 23g, female 38g of Zhenzi, 68g of Coptidis, 28g of Shayuanzi, 38g of Chinese Yam, 23g of Cucumber, 23g of Prunella vulgaris, 28g of Chushizi, 38g of Qingzhizi, 28g of Raspberry, 28g of Gujingcao, 33g of Orchid Herb and 28g of Ghost Needle. , to obtain the mixture, each use alcohol concentration of 90% ethanol 3kg reflux extraction 4 times, filter, combine the filtrate, concentrate under reduced pressure to a paste with a relative density of 1.20 (60°C), then dry and pulverize into powder, Dissolve the pulverized powder with 4% water relative to its mass, add 5% sodium hydroxide relative to the powder mass under stirring to help dissolve, adjust the pH value to 7, filter, and concentrate the filtrate under reduced pressure to a relative density of 1.30 (60 ℃) pa...

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PUM

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Abstract

The invention provides eye drops for epidemic keratoconjunctivitis. The eye drops are prepared from radix saposhnikoviae, senecio scandens, mint, centipeda minima, concha haliotidis, crocus sativus, white mulberry root-bark, borneol, semen cuscutae, ash bark, herba ecliptae, liriope spicata, honeysuckle, buddleja officinalis, plantain herbs, schizonepeta, glossy privet fruit, coptis chinensis, flatstem milkvetch seeds, Chinese yam, polygonum aviculare, prunella vulgaris, paper mulberry fruit, feather cockscomb seeds, raspberries, pipewort, common bluebeard herbs and sticktight. The eye drops have few side effects and are stable in treatment effect, reliable, high in safety and high in clinical application value.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to an eye drop for epidemic keratoconjunctivitis. Background technique [0002] Epidemic keratoconjunctivitis has a rapid onset and is mostly caused by adenovirus infection. If treatment is delayed, sequelae will be left. The damage to the cornea can last for several months or years, and even left corneal clouding affects vision. Epidemic keratoconjunctivitis, there may be a history of infection before the disease, and the incubation period is 5 to 7 days. The first eye will be affected first, and the other eye will be affected later, with foreign body sensation, itching, pain, watery mucus discharge, photophobia, tearing . Eyelid conjunctival congestion and edema, a large number of follicles in the conjunctival vault, subconjunctival hemorrhage and pseudomembrane formation may occur. After 1 to 2 weeks of onset, conjunctival inflammation gradually subsides, ...

Claims

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Application Information

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IPC IPC(8): A61K36/896A61K9/08A61P27/02A61P31/20A61K31/045
Inventor 不公告发明人
Owner 殷志杰
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