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High-stability disinfectant having high resistance to high temperature and high pressure

A high-stability, disinfectant technology, applied in the direction of disinfectants, waste disinfection or sterilization methods, biocides, etc., can solve the limited use of o-phthalaldehyde, poor sterilization effect and stability, and the degree of fungicide High stability, enhanced bactericidal ability and decontamination ability, and enhanced bactericidal ability

Inactive Publication Date: 2014-06-04
汪桂霞
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0018] Therefore the present invention mainly solves the technical problem: (1) sterilization under high temperature and high pressure in the prior art generally can only adopt the ethylene oxide that performance is single, the bactericidal spectrum is narrower; It is easy to be oxidized, unstable and other factors limit its scope of use; (3) in the prior art, bactericides, especially compound bactericides, have relatively high toxicity, or low tox

Method used

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  • High-stability disinfectant having high resistance to high temperature and high pressure
  • High-stability disinfectant having high resistance to high temperature and high pressure

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0041] Embodiment 1. The configuration of disinfectant:

[0042] (1) Component A: add 10.0g o-phthalaldehyde to 50.0g medical alcohol, stir to dissolve; B component: add 10.0g hydroxyquinoline to 50.0g medical alcohol, stir to dissolve; C component: Add 200.0g of cardanol to 200.0g of medical alcohol, stir to dissolve, then slowly add 20.0g of sodium hydroxide with a weight concentration of 40% under stirring, and stir to dissolve; (2) Mix component A with an appropriate amount of component C , Mix component B with the remainder of component C, then mix the above two parts of the solution, then add 80.0 g of polyethylene glycol and 380.0 g of medical alcohol, stir thoroughly to dissolve, and prepare 1000 g of the antibacterial agent.

Embodiment 2

[0043] Embodiment 2. The configuration of disinfectant:

[0044] (1) Component A: add 4.0g o-phthalaldehyde to 20.0g medical alcohol, stir to dissolve; B component: add 3.0g hydroxyquinoline to 20.0g medical alcohol, stir to dissolve; C component: Add 100.0g of cardanol to 100.0g of medical alcohol, stir to dissolve, then slowly add 10.0g of sodium hydroxide with a weight concentration of 40% under stirring, and stir to dissolve; (2) Mix component A with an appropriate amount of component C , Mix component B with the remaining component C, then mix the above two parts of the solution, then add 50.0g of polyethylene glycol and 693.0g of medical alcohol, and stir thoroughly to obtain 1000g of disinfectant.

Embodiment 3

[0045] Embodiment 3. Stability test of disinfectant:

[0046] According to the formula of Example 1, the ethanol of equal mass is used to replace the cardanol therein, and the comparison disinfectant is configured, which is hereinafter referred to as disinfectant 3. The disinfectants in Examples 1 and 2 are respectively referred to as disinfectant 1 and disinfectant 2. In the present embodiment, for the determination of o-phthalaldehyde, refer to the method of literature ("capillary gas chromatography is used to measure o-phthalaldehyde in disinfection products", the 23rd phase of Chinese Disinfection Science Impurity Volume 2006, the method of the 308-310 page) To measure.

[0047] Put 5mL of each disinfectant 1 and disinfectant 3 into sealed glass bottles, in triplicate x 4, store them in incubators at 37°C and 54°C for 14 days and 90 days respectively, then take them out and measure them respectively The content of phthalaldehyde is 100% with the content of phthalaldehyde...

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Abstract

The invention provides a high-stability disinfectant having high resistance to high temperature and high pressure, a preparation method thereof, and applications thereof in disinfection of medical waste. The disinfectant comprises following components: 0.05-1.5% of o-phthalaldehyde, 0.1-1.2% of hydroxyquinoline, 3-20% of cardanol, 1-10% of polyethylene glycol and 0.3-2% of sodium hydroxide having a concentration of 40%, with the balance being medicinal alcohol. The o-phthalaldehyde and the hydroxyquinoline are combined in scientific dosages. Experiments show that the o-phthalaldehyde and the hydroxyquinoline have synergetic antibacterial functions. The cardanol which is low in cost, easily available, safe and nontoxic is added into the disinfectant, and therefore the stability of effective disinfecting components is enhanced and the disinfectant can be used for disinfection at high temperature under high pressure. The cardanol also can generate wettability and decontamination capability which are similar to those of surfactants. At high temperature and under high pressure, the combination use of the disinfectant and propylene epoxide can achieve excellent disinfection performance.

Description

technical field [0001] The invention relates to a disinfectant, in particular to a highly stable high temperature and high pressure bottom eliminating agent, its preparation method and its application in medical waste disinfection. Background technique [0002] Medical waste is the clinical waste of the hospital, including discarded disposable medical supplies, such as dressings, pollutants and waste generated by laboratory tests, etc. Medical waste is different from ordinary domestic waste. It has strong biological toxicity, infectivity and corrosion. The bacteria, viruses and other pathogenic microorganisms contained in it are dozens or even hundreds of times that of ordinary domestic waste. There are many types and numbers of highly pathogenic bacteria and viruses, such as Escherichia coli, Shigella, typhoid bacillus, pneumococcus, beta hemolytic streptococcus, meningococcus, Staphylococcus aureus, Staphylococcus albus, Diphtheria bacillus, Yersinia pestis, Bacillus anth...

Claims

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Application Information

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IPC IPC(8): A01N25/22A01N25/30A01N43/42A01P1/00A01P3/00A61L11/00A01N35/04
Inventor 汪桂霞
Owner 汪桂霞
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