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Pharmaceutical composition for improving male animal sexual dysfunction

A composition and drug technology, applied in the direction of drug combination, disease, medical formula, etc., can solve problems such as unfavorable protection of traditional Chinese medicine plant varieties, semen transport obstacles, obstructive azoospermia, etc., to improve plasma testosterone levels, fertility The effect of improving and increasing sperm motility

Inactive Publication Date: 2014-07-30
SICHUAN SAINTHOOD BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] 2. Obstruction of insemination: such as lesions in the epididymis, vas deferens, ejaculatory duct and urethra, which can cause obstacles to semen delivery, usually clinically manifested as obstructive azoospermia;
However, in the current improved prescription of Wuzi Yanzong Pills, there are many prescriptions with more medicinal flavors, and the cost is higher, which is not conducive to the protection of traditional Chinese medicine plant varieties.

Method used

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  • Pharmaceutical composition for improving male animal sexual dysfunction

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0057] The preparation method of embodiment 1 pharmaceutical composition of the present invention

[0058] prescription:

[0059] Wolfberry 4kg Cuscuta (fried) 3kg Raspberry 2.5kg Schisandra (steamed) 1.2kg Plantain (salt fried) 1.25kg, yohimbine 2kg

[0060] Preparation method:

[0061] 1. Take schisandra, dodder, raspberry, medlar and plantain respectively, add water and decoct three times. Add water 6 times its weight for the first time, soak for 1 hour, then decoct for 2 hours; add water 5 times its weight for the second time, decoct for 1 hour; add water 4 times its weight for the third time, decoct 1 hour, filter, combine the filtrates, heat and concentrate to a relative density of 1.09-1.12 at 60-65°C;

[0062] 2. Spray-dry the above-mentioned concentrated solution through a high-speed centrifugal spray dryer to prepare 80-120 mesh dry extract powder;

[0063] 3. Take yohimbine, grind it and extract it with pH=2.5, 75% ethanol solution, the extraction temperature is...

Embodiment 2

[0065] Embodiment 2 The preparation method of pharmaceutical composition of the present invention

[0066] prescription:

[0067] Wolfberry 4kg Cuscuta (fried) 3kg Raspberry 2.5kg Schisandra (steamed) 1.2kg Plantain (salt fried) 1.25kg, yohimbine 2kg

[0068] Preparation method:

[0069] 1. Take schisandra, dodder, raspberry, medlar, psyllium and yohimbine respectively, add water and decoct three times. Add water 6 times its weight for the first time, soak for 1 hour, then decoct for 2 hours; add water 5 times its weight for the second time, decoct for 1 hour; add water 4 times its weight for the third time, decoct 1 hour, filter, combine the filtrates, heat and concentrate to a relative density of 1.09-1.12 at 60-65°C;

[0070] 2. Spray-dry the above-mentioned concentrated solution through a high-speed centrifugal spray dryer to prepare 80-120 mesh dry extract powder;

[0071] 3. The dry extract powder obtained in step 2 is prepared into granules by adding suitable auxili...

Embodiment 3

[0072] Embodiment 3 The preparation method of pharmaceutical composition of the present invention

[0073] Goji berry 6kg Cuscuta (fried) 4kg Raspberry 1.5kg Schisandra (steamed) 1kg Plantain (salt fried) 1kg, yohimbine 1.5kg

[0074] Preparation method:

[0075] 1. Take schisandra, dodder, raspberry, medlar, psyllium, yohimbine, add water and decoct three times. Add water 6 times its weight for the first time, soak for 1 hour, then decoct for 2 hours; add water 5 times its weight for the second time, decoct for 1 hour; add water 4 times its weight for the third time, decoct 1 hour, filter, combine the filtrates, heat and concentrate to a relative density of 1.09-1.12 at 60-65°C;

[0076] 2. Spray-dry the above-mentioned concentrated solution through a high-speed centrifugal spray dryer to prepare 80-120 mesh dry extract powder;

[0077] 3. Mix the dry extract powder obtained in step 2 with the yohimbine extract evenly, and then add suitable auxiliary materials to prepare a...

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Abstract

The invention provides a pharmaceutical composition for improving male animal sexual dysfunction. The pharmaceutical composition comprises the following material medicines in parts by weight: 4-6 parts of fruits of Chinese wolfberry, 2-4 parts of seeds of Chinese dodder, 1.5-3.5 parts of raspberries, 1-2 parts of schisandra chinensis, 1-2 parts of semen plantaginis and 1.5-2.5 parts of yohimbine. According to the invention, the five traditional Chinese medicines such as fruits of Chinese wolfberry, seeds of Chinese dodder, and the like are matched with the yohimbine extract to use, so that the improvement effect on male animal sexual dysfunction is obviously superior to that of the classical prescription wuzi yanzong pill; and meanwhile, after being matched for use, the medicines effectively avoid adverse reaction of the yohimbine, so that a safer and more effective novel choice is provided for clinical medication.

Description

technical field [0001] The invention relates to a pharmaceutical composition for improving the reproductive system function of male animals, a preparation method and application thereof. Background technique [0002] In recent years, due to the influence of psychological, environmental, social and other factors, the fertility of couples of childbearing age in the world has been declining year by year, and most of the reasons are caused by the decline of male fertility. Male infertility, that is, reproductive system dysfunction, mainly has two reasons, one is the low quality of semen, and the other is male sexual dysfunction. [0003] Among them, male infertility caused by semen quality problems can be attributed to the following three reasons: [0004] 1. Abnormal semen: mainly including azoospermia, oligospermia and weak semen, blood semen, deformed sperm and dead sperm, etc.; [0005] 2. Obstruction of insemination: such as lesions in the epididymis, vas deferens, ejacul...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/815A61P15/08A61P15/00
CPCA61K36/39A61K36/57A61K36/68A61K36/73A61K36/815C07D459/00
Inventor 罗明锋郭小雪李改丽
Owner SICHUAN SAINTHOOD BIOTECH
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