Polypeptide, polypeptide derivative, medicinal salt of polypeptide and pharmaceutical composition

A technology of peptide derivatives and compositions, applied in the directions of drug combinations, microorganisms, biochemical equipment and methods, etc., can solve problems such as short plasma half-life, achieve long plasma half-life, improve islet function and good stability.
CN104045702AInactive Publication Date: 2014-09-17SHENZHEN HIGHTIDE BIOPHARM

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
SHENZHEN HIGHTIDE BIOPHARM
Publication Date
2014-09-17
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention provides a polypeptide. The polypeptide solves the problem that the existing polypeptide for promoting islet neogenesis has a short plasma half-life and low activity. The invention also discloses a derivative of the polypeptide, a medicinal salt of the polypeptide and a pharmaceutical composition. The polypeptide has high stability in blood and a long half life.
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Description

[0001] This application is based on, and claims priority from, an earlier PCT international application (application number PCT / CN2013 / 072771) filed on March 15, 2013, the entire content of which is hereby incorporated by reference into this application. technical field

[0002] The present invention mainly relates to the fields of medicine and pharmacy, especially a polypeptide, derivatives of the polypeptide, pharmaceutically acceptable salts and pharmaceutical compositions. Background technique

[0003] More than 300 million people worldwide suffer from and suffer from diabetes mellitus (DM). There are two main types of diabetes: type 1 diabetes (T1D) and type 2 diabetes (T2D). Type 1 diabetes is caused by the body's inability to produce insulin and the patient needs to be treated with daily insulin. Type 2 diabetes is caused by insulin resistance, which means that the body's cells cannot use insulin properly. At present, there are many proven and effective non-insulin t...

Claims

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