Compound raceanisodamine hydrochloride injection and preparation method thereof

A technology of anisodamine and injection, which is applied in the field of compound racemic anisodamine hydrochloride injection and its preparation, can solve problems such as infection and lower curative effect, and achieve the effects of relieving body stress response, enhancing curative effect, and wide clinical application

Inactive Publication Date: 2014-12-03
TIANJIN BIJIA BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The main pathogenic bacteria of bacillary dysentery are Escherichia coli, Salmonella, Listeria, etc. Under normal circumstances, these bacteria do not cause disease under normal conditions in the body, but when the resistance decreases or the environment changes, these bacteria Potential to become pathogenic and cause infection, leading to severe diarrhea
In recent years, aminoglycosides, quinolones, etc. have been listed as the first-selected drugs for the treatment of bacillary dysentery infection. Due to the long-term repeated use of an antibiotic, the pathogenic microorganisms have a strong resistance (resistance) to the drug, reducing the risk of infection. curative effect

Method used

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  • Compound raceanisodamine hydrochloride injection and preparation method thereof
  • Compound raceanisodamine hydrochloride injection and preparation method thereof
  • Compound raceanisodamine hydrochloride injection and preparation method thereof

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Embodiment Construction

[0018] Below in conjunction with the examples, the present invention is further described, the following examples are illustrative, not limiting, and the protection scope of the present invention cannot be limited by the following examples.

[0019]

[0020] Below take embodiment 1 as example to illustrate the preparation method of compound racemic anisodamine hydrochloride injection: the steps are as follows:

[0021] (1) Take by weight 50 parts of pefloxacin mesylate, 20 parts of gentamicin sulfate-micronomycin, 5 parts of racemic anisodamine hydrochloride;

[0022] (2) Get 700 parts of water for injection, add pefloxacin mesylate, racemic anisodamine hydrochloride, genta-micronomycin sulfate successively and stir to dissolve;

[0023] (3) Keep it for 20-30 minutes, adjust the pH to 3.5-5.5 after the liquid is clear, and finally add water for injection to 1000 parts to prepare a compound racemic anisodamine hydrochloride injection.

[0024] The application of a compound ...

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Abstract

The invention discloses a compound raceanisodamine hydrochloride injection. The compound raceanisodamine hydrochloride injection comprises, by weight, 20-100 parts of pefloxacin mesylate, 1-40 parts of gentamycin sulfate-micronomicin, 1-10 parts of raceanisodamine hydrochloride and 800-1000 parts of injection water. The compound raceanisodamine hydrochloride injection has high effects on bacterial diarrhea of dogs, foxes and racoon dogs, can treat both symptoms and root causes and can relieve infected animal body stress reactions. The compound raceanisodamine hydrochloride injection comprises pefloxacin mesylate, gentamycin sulfate-micronomicin and raceanisodamine hydrochloride, has substantial effects on dogs, foxes and racoon dogs, and can relieve infected animal body stress reactions. An experiment proves that through combination of pefloxacin mesylate, gentamycin sulfate-micronomicin and raceanisodamine hydrochloride, the compound raceanisodamine hydrochloride injection can improve curative effects, has a wide clinical application range, can be widely used in dog, fox and racoon dog gastrointestinal tracts infected by bacteria, can improve dog, fox and racoon dog survival rates and can improve dog, fox and racoon dog body weights.

Description

technical field [0001] The invention belongs to the field of veterinary drug injections, in particular to a compound racemic anisodamine hydrochloride injection suitable for treating bacterial gastrointestinal tract infections in dogs, foxes and raccoon dogs and a preparation method thereof. Background technique [0002] Bacillary dysentery is a disease that dogs, foxes, and raccoon dogs are very susceptible to. It can cause dehydration, weakness, poor growth, and even death in dogs, foxes, and raccoon dogs. [0003] The main pathogenic bacteria of bacillary dysentery are Escherichia coli, Salmonella, Listeria, etc. Under normal circumstances, these bacteria do not cause disease under normal conditions in the body, but when the resistance decreases or the environment changes, these bacteria There is a possibility of becoming pathogenic and causing an infection, leading to severe diarrhea. In recent years, aminoglycosides, quinolones, etc. have been listed as the first-selec...

Claims

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Application Information

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IPC IPC(8): A61K9/08A61K31/7036A61P31/04A61P1/12A61K31/496A61K31/46
CPCY02A50/30
Inventor 张伟
Owner TIANJIN BIJIA BIOTECH
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