Gastrointestinal contrast agent and preparation method thereof
A technology for gastrointestinal imaging and traditional Chinese medicine, which is applied in the preparation of X-ray contrast agents, pharmaceutical formulations, and medical preparations containing active ingredients, etc. High safety and comfort, remarkable acid suppression effect, stable physical and chemical properties
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[0025] The invention also provides a preparation method of a gastrointestinal contrast agent, which is characterized in that it is prepared by mixing and mixing 60-80 parts by weight of barium sulfate and 10-20 parts by weight of a traditional Chinese medicine extract.
[0026] According to the traditional Chinese medicine composition and preparation principles, the present invention carefully develops the traditional Chinese medicine composition, and provides a kind of Chinese medicine extract that has the advantages of strong pertinence, good curative effect, short cycle, low price, and no toxic and side effects, and can be accepted by patients. gastrointestinal contrast agent.
Embodiment 1
[0029] Take honeysuckle 10g, astragalus 10g, licorice 15g, Atractylodes macrocephala 20g, poria cocos 20g, angelica 10g, yam 20g, medlar 20g, plantain 10g, hawthorn 20g, codonopsis 10g, jujube 15g, Chuanqiong 10g, rehmannia glutinosa 10g, tangerine peel 10g, Ligustrum lucidum 10g, chopped and put into 6 times the amount of water, heated and refluxed twice, 40 minutes each time, to extract the active ingredient, combined the 2 extracts and let stand; put the dregs extracted with water into 6 times the amount in ethanol, heated and refluxed for 2 extractions, each time for 35 minutes, the 2 extracts were combined and left standing; the above two extracts were combined, the ethanol was recovered under reduced pressure and concentrated until the concentration of the medicinal solution was 0.6g crude drug / mL. After filtration, the relative density of the filtrate is about 1.18 at 20°C; reduce the pressure to 0.04MPa, keep the temperature at 60°C, concentrate to a relative density of...
Embodiment 2
[0031]Take 30g honeysuckle, 20g astragalus, 30g licorice, 30g Atractylodes macrocephala, 30g poria cocos, 20g angelica, 30g yam, 30g wolfberry, 20g plantain, 30g hawthorn, 20g codonopsis, 30g jujube, 20g Chuanqiong, 20g rehmannia glutinosa, 25g tangerine peel, Ligustrum lucidum 20g, chopped and put into 6 times the amount of water, heated and refluxed for 2 extractions, 1 hour each time, to extract the active ingredients, combined the 2 extracts and left standing; put the dregs extracted with water into 6 times the amount of water in ethanol, heated and refluxed twice for 55 minutes each time, and the two extracts were combined and left standing; the above two extracts were combined, and the ethanol was recovered under reduced pressure and concentrated until the concentration of the medicinal solution was 0.6g crude drug / mL. After filtration, the relative density of the filtrate is about 1.18 at 20°C; depressurize to 0.07MPa, keep the temperature at 80°C, concentrate to a relat...
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