5 results about "Acid inhibition" patented technology

This invention provides an oral hydrogel microsphere for targeted intestinal inhibition of gout, its preparation method, and its application, belonging to the field of biomedical technology. The preparation method of the oral hydrogel microsphere of this invention includes the following steps: (1) dissolving uricase and dopamine in sodium alginate solution, controlling the concentration of uricase to 10-20 U / mg and the concentration of dopamine to 0.01-0.1 g / ml, and then dispersing by ultrasound; (2) placing the solution obtained in step (1) in a microfluidic device, and using gas microfluidic technology, shearing the solution into uniform droplets under the action of nitrogen flow; (3) dropping the droplets obtained in step (2) into calcium chloride solution, and cross-linking to form the oral hydrogel microsphere for targeted intestinal inhibition of gout. This invention successfully constructs intestinal "bursting" oral hydrogel microspheres loaded with uricase, effectively immobilizing uricase in the intestinal mucosa, thereby inhibiting gout for the first time by excreting free uric acid through the intestine. The microspheres have high uricase activity and good therapeutic effect on gout.

The present application belongs to the field of solid waste resource utilization and biological fermentation technology, and particularly relates to a method for producing L-lactic acid by anaerobic fermentation of kitchen waste by using biochar and alkaline salt in cooperation. In the method, biochar and alkaline salt are added to kitchen waste slurry for anaerobic fermentation to obtain L-lactic acid. In the method, the synergistic effect of biochar and alkaline salt accelerates the decomposition of substrate, shortens the fermentation period, solves the acid inhibition problem, significantly improves the lactic acid yield and the purity of L-lactic acid, and is simple to operate, with controllable and easily available raw materials, thereby significantly reducing the cost and providing a new feasible path for the large-scale production of L-lactic acid.

The invention discloses full-amount resourceful treatment equipment for livestock and poultry manure. The full-amount resourceful treatment equipment comprises a first reactor located at an anaerobic acid production stage and a second reactor located at an anaerobic methane production stage, the first reactor is communicated with the second reactor; wherein the first reactor and the second reactor are both internally provided with anode parts of a parallel circuit, the device further comprises a treatment device of a product of the second reactor, and the treatment device is internally provided with an oxygen supply device and a cathode part of the parallel circuit. The first reactor and the second reactor are utilized to realize segmented reaction and function complementation, so that the operation stability and the organic matter removal efficiency of the treatment system can be effectively improved; meanwhile, the acid inhibition effect can be remarkably relieved through a segmented operation mechanism. The invention further discloses a full-amount resourceful treatment method for the livestock and poultry manure.