16 results about "Dithiete" patented technology

This invention relates to a non-natural methionine and its synthesis method, using inexpensive and readily available transition metals as catalysts. N Using arylglycine, styrene compounds, and disulfides as raw materials, a series of non-natural methionine compounds were obtained with high selectivity and high yield through a three-component reaction under mild conditions. The compounds prepared in this invention are multifunctional non-natural methionine derivatives, representing a novel class of natural methionine derivatives. They can be used in drug modification, biosensor fabrication, and other fields, possessing significant research and application value and providing new synthetic strategies for the preparation of novel peptide drugs.

This invention relates to a method for synthesizing aromatic carbon-10 sulfur-containing compounds from isoprene. Specifically, using disulfide, isoprene, and 2-methyl-1-buten-3-yne as raw materials, aromatic carbon-10 sulfur-containing compounds are constructed under cobalt catalyst and iodine tandem catalysis. This invention has the following advantages: the raw materials are simple and readily available, the synthesis is simple, it is environmentally friendly, the conditions are mild, and it has high atom economy. The compounds obtained from the bulk chemical isoprene have structures similar to natural terpenes and represent an important class of terpenes.

The invention discloses a Karl Fischer moisture determination method for sulfur-containing organic compounds, and belongs to the technical field of chemical analysis. The method comprises the following steps: adding absolute methanol, imidazole and an inhibitor (selected from N-substituted maleimide or acrylate compounds) into a titration system, then adding a sample, and titrating with a pyridine-containing Karl-Fischer reagent to the end point. The inhibitor can effectively capture reducing sulfur species and eliminate interference of the reducing sulfur species on iodine. Experiments show that for sulfur-containing samples such as 2, 2-dimethylthiopropane, dimethyl sulfide, dimethyl disulfide and the like, the deviation reduction rate of the method is more than 60% compared with that of a traditional method; the method is easy and convenient to operate, high in accuracy and suitable for moisture analysis of sulfur-containing organic matter in the fields of petrifaction, pharmacy and the like.

The application belongs to the technical field of organic synthesis, and particularly relates to a method for synthesizing 1-(2,4-dimethylphenyl)thio-N-benzyl-2-naphthylamine by a continuous flow light-heat integrated method. The method is performed in a micro-channel reaction device provided with light and heat. N-benzyl-2-naphthylamine, 2,2',4,4'-tetramethyl diphenyl disulfide and a catalyst sodium iodide are dissolved in acetonitrile solvent to obtain a reaction solution. A blue light is used as a light source of a reaction module, and the temperature is adjusted to 25-60 DEG C. Air or oxygen is introduced into the reaction solution, and magnetic stirring is performed. Then, the gas-liquid mixed reaction solution is input into the reaction module through a peristaltic pump to obtain 1-(2,4-dimethylphenyl)thio-N-benzyl-2-naphthylamine. The application creatively uses the continuous flow light-heat integrated reaction technology to synthesize 1-(2,4-dimethylphenyl)thio-N-benzyl-2-naphthylamine, greatly improves the reaction efficiency, shortens the reaction time, improves the safety and controllability of the reaction, solves the amplification effect of the conventional reaction, and provides a reaction technology without bottleneck amplification for the synthesis of the compound.

This invention relates to a weather-resistant and anti-aging coating for coastal port cranes and its preparation method, belonging to the field of coating materials technology. The coating comprises component A and component B; component A includes an isocyanate-terminated prepolymer, a tri(dibenzoylmethane) ytterbium(III) complex, a spiropyran derivative, and additives; component B is obtained by dissolving isophorone diamine and 2,2'-diaminodiphenyl disulfide in ethyl acetate solvent, with a solid content of 40-60 wt%, and a molar ratio of isophorone diamine to 2,2'-diaminodiphenyl disulfide of (1-4):1; the molar ratio of isocyanate groups in component A to imino groups in component B is (1-1.05):1. This invention accelerates the exchange of dynamic disulfide bonds by constructing a photothermal conversion system, thereby enhancing the coating's ability to dissipate mechanical stress under ultraviolet light irradiation and simultaneously imparting long-term weather resistance to the coating.

The invention discloses a preparation method of a fluorine-substituted trans-olefin compound. Specifically, the invention discloses a preparation method of a compound as shown in a formula VII, which comprises the following steps: in a solvent, in the presence of a free radical initiator and a free radical source, a compound as shown in a formula VI-1 is subjected to an isomerization reaction to prepare the compound as shown in the formula VII, the free radical initiator is dimethyl azobis (2-methylpropionate), and the free radical source is dimethyl azobis (2-methylpropionate). The free radical source is diphenyl disulfide.

The application discloses a preparation method of an ultraviolet curing antistatic coating and relates to the technical field of antistatic coatings. In the application, hydrochloric acid doped polyaniline is used as a core material, 1-butyl-3-methyl imidazole bistrifluoromethanesulfonylimide ionic liquid is introduced as a dopant, and the carrier mobility of the polyaniline is significantly improved. Urea-formaldehyde resin is used as a wall material to coat the surface of the polyaniline to form microcapsules. The microcapsules release polyaniline and ionic liquid compounds after being broken to fill the crack gap. Secondly, 3,3'-dihydroxy diphenyl disulfide and acryloyl chloride are used as raw materials to generate a disulfide bond diacrylate monomer through an esterification reaction. The monomer, tetra(3-mercaptopropionic acid) pentaerythritol ester crosslinking agent and epoxy vinyl ester resin form a three-dimensional crosslinking network. The mercapto groups in the crosslinking agent and the acrylate groups of the disulfide bond diacrylate monomer undergo a click reaction to realize the topological structure reorganization of the molecular chain. The coating prepared by the application has the effect of long-acting antistatic.

This invention belongs to the field of organic synthesis and relates to a method for preparing organosulfur ether compounds using photocatalysis. A disulfide compound 1 and tetrahydrofuran undergo a coupling reaction under the action of a base and a catalyst, and under ultraviolet light irradiation, to obtain organosulfur ether compound 3. This invention provides a novel method for preparing organosulfur compounds. Under light irradiation, a photocatalyst extracts hydrogen atoms from tetrahydrofuran to obtain alkyl radicals, which are then converted into carbocations through redox reactions. Simultaneously, the disulfide ether generates sulfur radicals under light irradiation, which produce sulfide anions under alkaline conditions. The sulfide anions and carbocations then undergo a coupling reaction to obtain sulfide compounds. The method provided by this invention is rationally designed, with mild reaction conditions, is environmentally friendly, and has low cost, achieving a yield of up to 91%. It provides a new method for the synthesis of organosulfur ether compounds and has promising industrial applications.

The application belongs to the field of novel functional materials, and particularly relates to a high-recovery self-healing polyurethane elastomer material and a preparation method thereof. The self-healing elastomer material is prepared from the following components: 50-100 parts by weight of a polyurethane prepolymer, and 13-28 parts by weight of a chain extender composition. The polyurethane prepolymer is obtained from a polyol with a molecular weight of 2000 and isophorone diisocyanate under catalytic reaction of dibutyltin dilaurate. The chain extender is a combination of a pendant chain chain extender, 4,4'-diamino diphenyl disulfide and 4,4'-diamino diphenyl ethane. The solvent is N,N-dimethylacetamide. The polyurethane elastomer provided by the application has a self-healing performance recovery rate of more than 90% at 60 DEG C for 12 hours, is suitable for precision instrument laboratory floor coating, medical materials and aerospace fields, realizes scratch self-repairing, and prolongs the service life.

The invention discloses a method for rapidly preparing aza-aryl thioether compounds through mechanical piezoelectric catalysis C-S coupling reaction. According to the technical scheme, a chlorinated aza-aryl compound and a disulfide compound are used as raw materials, and a C-S coupling reaction is carried out under the conditions of normal temperature, normal pressure and air in a Ni catalysis and trace liquid auxiliary mechanical grinding mode to prepare a series of aza-aryl sulfide coupling products in a green and safe mode. According to the invention, a mechanical force method is adopted to rapidly and simply carry out C-S coupling reaction to prepare an organic sulfide intermediate or carry out thioetherification modification on molecules, the operation and treatment method is simple, the reaction mode is green and safe and is environment-friendly, BaTiO3 / Zn / Ni concerted catalysis is adopted, the reaction condition is mild, and the reaction can be completed in 100 minutes.

The present application relates to the field of organic synthesis, and is a preparation method of imidazo six-membered nitrogen heterocyclic compounds containing isothiourea fragments for medicines and intermediates. The method uses nitrogen atom ortho isocyanomethyl-substituted pyridine, pyrimidine, pyrazine, quinoline and other nitrogen-containing heteroaromatic rings as raw materials, reacts with various disulfides under the action of N-chlorosuccinimide (NCS) and a catalytic amount of TEMPO, and intramolecularly cyclizes to form imidazo six-membered nitrogen heterocyclic compounds containing isothiourea fragments. The method can realize intramolecular ring closure in one step, form imidazo[1,5a] nitrogen-containing heteroaromatic rings containing isothiourea fragments, construct various imidazo[1,5a] nitrogen-containing heteroaromatic rings containing isothiourea fragments, has high yield, low raw material cost, can realize large-scale industrial production, and has market application prospect.

The invention relates to a high-durability self-healing polyimide-based flexible sensing base material and a preparation method of the high-durability self-healing polyimide-based flexible sensing base material. The high-durability self-healing polyimide-based flexible sensing base material is prepared from the following components in parts by weight: 80 to 90 parts of dynamic modified polyimide matrix, 5 to 10 parts of silane coupling agent KH-580 modified Ti < 3 > C < 2 > T < x > MXene, 4 to 8 parts of self-healing microcapsule and 1 to 3 parts of polycaprolactone-polyethylene glycol segmented copolymer, wherein the dynamic modified polyimide matrix is prepared by copolymerization of 3, 3 ', 4, 4'-benzophenone tetracarboxylic dianhydride, 4, 4 '-diaminodiphenyl disulfide and dimercaptopropionic acid; a core material of the self-healing microcapsule is an isocyanate-polyol prepolymer, and a wall material of the self-healing microcapsule is urea resin. The high-durability self-healing polyimide-based flexible sensing base material disclosed by the invention is high in self-healing capability and high in durability.

The invention belongs to the technical field of high-performance functional polymer materials, and discloses a preparation method of self-repairing toughening type epoxy modified cyanate resin. The preparation method comprises the following steps: taking a disulfide bond-containing 4, 4 '-diaminodiphenyl disulfide-terminated polyurethane oligomer curing agent as a disulfide bond curing agent; reacting metal salt, a pyridylamine compound and the isocyanate-terminated polyurethane oligomer to prepare a pyridine latent curing agent; the preparation method comprises the following steps: carrying out pre-coordination reaction on a disulfide bond curing agent, a pyridine latent curing agent and matrix resin, and curing to obtain the epoxy modified cyanate resin. The invention also discloses application of the epoxy modified cyanate resin obtained by the preparation method in the field of automobile lightweight structural members or radar wave-transparent structural members. The disulfide bond curing agent and the pyridine latent curing agent are adopted, and dynamic disulfide bonds and pyridylamine-metal ligands in a cross-linked network form a multi-layer energy dissipation structure, so that the toughness and the self-repairing capability of the epoxy modified cyanate resin can be synergistically improved.

The application provides a preparation method of a disulfide pre-sulfurizing agent and application of an amino acid in the method. The amino acid is used as a catalyst, and the disulfide pre-sulfurizing agent with a yield not less than 95% and controllable molecular size can be prepared under normal temperature in an oxygen or air atmosphere. The reaction condition is more moderate, the energy consumption is smaller, the physical hazard is weaker, the health and environmental hazards are lower, and the method is beneficial to the use safety of equipment and prolongs the service life of the equipment in the pre-sulfurization process of a hydrogen sulfide agent.

This invention discloses a method for preparing asymmetric diphenyl sulfide compounds. Disubstituted phenyl disulfide and lithium chloride-containing substituted phenyl magnesium halide (Knochel-type Grignard reagent) are dissolved in an organic solvent, and the reaction is stirred at room temperature while the reaction progress is monitored using gas chromatography. After approximately 2 hours, the reaction proceeds completely. The reaction solution is extracted with ethyl acetate, dried over anhydrous sodium sulfate, and concentrated under reduced pressure to obtain a crude product. Subsequently, the crude product is purified by column chromatography to obtain the desired asymmetric diphenyl sulfide compounds. This method uses disubstituted phenyl disulfide and lithium chloride-containing substituted phenyl magnesium halide (Knochel-type Grignard reagent) as starting materials to synthesize asymmetric diphenyl sulfide compounds. The synthetic route is simple, requires no external transition metal catalyst, exhibits good functional group tolerance, can be scaled up, and is easy for industrial production.

This invention discloses a class of 5H-[1,2,4]triazinyl[5,6-b]indole-3-thione derivatives with disulfide structures, using 5H-[1,2,4]triazinyl[5,6-b]indole structures as lead compounds and alkyl or aryl thiols as linking groups. Different pharmacophores are then added to these compounds to synthesize a series of 5H-[1,2,4]triazinyl[5,6-b]indole derivatives. These compounds exhibit excellent inhibitory effects against plant pathogenic bacteria such as *Bacillus thuringiensis* (rice bacterial blight) and *Citrus canker* (citrus canker). Some compounds show excellent inhibitory activity against *Bacillus thuringiensis*, with EC50... 50 The concentration can reach 0.77–0.85 μg / mL; some compounds showed excellent inhibitory activity against *Citrus canker*, the causal agent of citrus canker, with EC50 levels of [missing information]. 50 The concentration is 2.62 μg / mL. The disulfide structure 5H-[1,2,4]triazine[5,6-b]indole derivative disclosed in this invention can be used to prepare pesticides against plant pathogenic bacteria and fungi, and has extremely high research value.